Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 9
Submit an article Journal homepage
371
Views
15
CrossRef citations to date
0
Altmetric
General Xenobiochemistry

Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes

Risto O. JuvonenSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland; Correspondence[email protected]
,
Mira AhinkoDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyvaskyla, Jyvaskyla, Finland;
,
Juhani HuuskonenDepartment of Chemistry, University of Jyvaskyla, Jyvaskyla, Finland;
,
Hannu RaunioSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland;
&
Olli T. PentikäinenDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyvaskyla, Jyvaskyla, Finland; ;Institute of Biomedicine, Faculty of Medicine Integrative Physiology and Pharmacology, University of Turku, Turku, FinlandCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-7188-4016
ORCID Icon
Pages 1015-1024 | Received 10 Aug 2018, Accepted 26 Sep 2018, Published online: 29 Nov 2018

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Risto O. Juvonen, Elmeri M. Jokinen, Juhani Huuskonen, Olli Kärkkäinen, Hannu Raunio & Olli T. Pentikäinen. (2021) Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13. Xenobiotica 51:11, pages 1207-1216.
Read now
Guang Tian, Zixin Zhang, Haidi Li, Dongsheng Li, Xinrui Wang & Chuanguang Qin. (2021) Design, Synthesis and Application in Analytical Chemistry of Photo-Sensitive Probes Based on Coumarin. Critical Reviews in Analytical Chemistry 51:6, pages 565-581.
Read now

Articles from other publishers (13)

Anna-Mari Kok, Risto Juvonen, Markku Pasanen, Vusani Mandiwana, Michel Lonji Kalombo, Suprakas Sinha Ray, Rirhandzu Rikhotso-Mbungela & Namrita Lall. (2024) Evaluation of Lippia scaberrima Sond. and Aspalathus linearis (Burm.f.) R. Dahlgren extracts on human CYP enzymes and gold nanoparticle synthesis: implications for drug metabolism and cytotoxicity. BMC Complementary Medicine and Therapies 24:1.
Crossref
Ayano Ikemura, Yukiko Karuo, Yuki Uehashi, Tomohiro Agou, Masahiro Ebihara, Yasuhiro Kubota, Toshiyasu Inuzuka, Masaaki Omote & Kazumasa Funabiki. (2024) 3-Perfluoroalkylated fluorescent coumarin dyes: rational molecular design and photophysical properties. Molecular Systems Design & Engineering 9:4, pages 332-344.
Crossref
Markus Koponen, Jaana Rysä, Anna-Kaisa Ruotsalainen, Olli Kärkkäinen & Risto O. Juvonen. (2023) Western Diet Decreases Hepatic Drug Metabolism in Male LDLr−/−ApoB100/100 Mice. Journal of Nutrition and Metabolism 2023, pages 1-12.
Crossref
Y. V. Faletrov, V. O. Maliugin, N. S. Frolova & V. M. Shkumatov. (2022) <i>In silico</i> evaluation of new affine interactions of methylcoumarin with cytochromes P450. Proceedings of the National Academy of Sciences of Belarus, Chemical Series 58:2, pages 186-190.
Crossref
Michaela Šadibolová, Risto O. Juvonen, Seppo Auriola & Iva Boušová. (2022) In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity. Archives of Toxicology 96:3, pages 793-808.
Crossref
S. Kumar, N. Vashisht, Aruna & S. P. Sharma. (2021) One-Pot Green Synthesis of 2-Oxo-2H-chromene-3-carbonitriles Using Dual-Frequency Ultrasonication. Russian Journal of Organic Chemistry 57:9, pages 1508-1512.
Crossref
Sanna Niinivehmas & Olli Pentikäinen. (2021) Coumarins as Tool Compounds to Aid the Discovery of Selective Function Modulators of Steroid Hormone Binding Proteins. Molecules 26:17, pages 5142.
Crossref
Hafiz Ishfaq Ahmad, Gulnaz Afzal, Adil Jamal, Shumaila Kiran, Musarrat Abbas Khan, Khalid Mehmood, Zahid Kamran, Irfan Ahmed, Shakeel Ahmad, Asmar Ahmad, Javed Hussain & Sadaf Almas. (2021) In Silico Structural, Functional, and Phylogenetic Analysis of Cytochrome (CYPD) Protein Family. BioMed Research International 2021, pages 1-13.
Crossref
Risto O. Juvonen, Mira Ahinko, Elmeri M. Jokinen, Juhani Huuskonen, Hannu Raunio & Olli T. Pentikäinen. (2021) Substrate Selectivity of Coumarin Derivatives by Human CYP1 Enzymes: In Vitro Enzyme Kinetics and In Silico Modeling. ACS Omega 6:17, pages 11286-11296.
Crossref
Alexander Strom, Rachit Shah & Carston R. Wagner. (2021) “Switching On” Enzyme Substrate Specificity Analysis with a Fluorescent Competitive Inhibitor. Biochemistry 60:6, pages 440-450.
Crossref
Hannu Raunio, Olli Pentikäinen & Risto O. Juvonen. (2020) Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro. International Journal of Molecular Sciences 21:13, pages 4708.
Crossref
Risto Olavi Juvonen, Elmeri Matias Jokinen, Adeel Javaid, Marko Lehtonen, Hannu Raunio & Olli Taneli Pentikäinen. (2020) Inhibition of human CYP1 enzymes by a classical inhibitor α‐naphthoflavone and a novel inhibitor N ‐(3, 5‐dichlorophenyl)cyclopropanecarboxamide: An in vitro and in silico study . Chemical Biology & Drug Design 95:5, pages 520-533.
Crossref
Anna-Mari Reid, Risto Juvonen, Pasi Huuskonen, Marko Lehtonen, Markku Pasanen & Namrita Lall. (2019) In Vitro Human Metabolism and Inhibition Potency of Verbascoside for CYP Enzymes. Molecules 24:11, pages 2191.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.