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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 9
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Clinical Pharmacokinetics and Metabolism

Absorption, distribution, metabolism, and excretion of radiolabeled naldemedine in healthy subjects

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Pages 1044-1053 | Received 13 Aug 2018, Accepted 12 Oct 2018, Published online: 04 Jan 2019

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Flaminia Coluzzi, Maria Sole Scerpa & Joseph Pergolizzi. (2020) Naldemedine: A New Option for OIBD. Journal of Pain Research 13, pages 1209-1222.
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Yuki AzumaKatsumi KoikeHiroki ChibaAki MitamuraHiroki TsujiSachiko KawasakiTakaaki YokotaToshiyuki KanemasaYasuhide MoriokaTsutomu Suzuki & Masahide Fujita. (2023) Efficacy of Naldemedine on Intestinal Hypomotility and Adhesions in Rodent Models of Postoperative Ileus. Biological and Pharmaceutical Bulletin 46:12, pages 1714-1719.
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Simon G. Wong & Shuguang Ma. 2023. Overcoming Obstacles in Drug Discovery and Development. Overcoming Obstacles in Drug Discovery and Development 137 174 .
Joelle BouSaba, Wassel Sannaa & Michael Camilleri. (2022) Update on the role of naldemedine in opioid-induced constipation in patients with chronic noncancer pain. Therapeutic Advances in Gastroenterology 15, pages 175628482210786.
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A. N. Nagappa & Shvetank Bhatt. 2022. Perspectives in Pharmacy Practice. Perspectives in Pharmacy Practice 247 254 .
Kazuya Fukumura, Nao Kawaguchi, Toru Ishibashi, Ryuji Kubota, Yukio Tada & Eriko Ogura. (2020) Clinical Drug-Drug Interaction Studies to Evaluate the Effects of a P-Glycoprotein Inhibitor, CYP3A Inhibitors, and a CYP3A Inducer on the Pharmacokinetics of Naldemedine in Healthy Subjects. Clinical Drug Investigation 40:6, pages 529-540.
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Ricard Mesía, Juan Antonio Virizuela Echaburu, Jose Gómez, Tamara Sauri, Gloria Serrano & Eduardo Pujol. (2019) Opioid-Induced Constipation in Oncological Patients: New Strategies of Management. Current Treatment Options in Oncology 20:12.
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