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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 10
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General Xenobiochemistry

The effects of para-phenylenediamine (PPD) on the skin fibroblast cells

Enayatollah SeydiDepartment of Occupational Health and Safety Engineering School of Health, Alborz University of Medical Sciences, Karaj, Iran; View further author information
,
Mohsen FatahiDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran; View further author information
,
Parvaneh NaserzadehPharmaceutical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranView further author information
&
Jalal PourahmadDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Correspondence[email protected]
View further author information
Pages 1143-1148 | Received 19 Aug 2018, Accepted 24 Oct 2018, Published online: 17 Jan 2019

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Kevin M. Towle, Ruth Y. Hwang, Ernest S. Fung, Dana M. Hollins & Andrew D. Monnot. (2020) Hair dye and risk of skin sensitization induction: a product survey and quantitative risk assessment for para-phenylenediamine (PPD). Cutaneous and Ocular Toxicology 39:4, pages 311-316.
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Articles from other publishers (17)

Chenyang Rao, Fuhao Chu, Fang Fang, Dongfang Xiang, Bo Xian, Xiaying Liu, Shaopan Bao & Tao Fang. (2024) Toxic effects and comparison of common amino antioxidants (AAOs) in the environment on zebrafish: A comprehensive analysis based on cells, embryos, and adult fish. Science of The Total Environment 924, pages 171678.
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Wei Wang, Yi Chen, Jiacheng Fang, Feng Zhang, Guangbo Qu & Zongwei Cai. (2024) Toxicity of substituted p-phenylenediamine antioxidants and their derived novel quinones on aquatic bacterium: Acute effects and mechanistic insights. Journal of Hazardous Materials 469, pages 133900.
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Hajra Farooq, Pauras Mhatre, Riya Aggarwal, Mahalia T. Robinson, Emily Joseph, James Segars & Bhuchitra Singh. (2024) A systematic review of association between use of hair products and benign and malignant gynecological conditions. European Journal of Obstetrics & Gynecology and Reproductive Biology 295, pages 160-171.
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Moein Safarkhani, Amirhossein Ojaghi, Shefa Mirani Nezhad, Hossein Daneshgar, Ana Cláudia Paiva-Santos, Fatemeh Radmanesh, Mojtaba Bagherzadeh, Ehsan Nazarzadeh Zare, Navid Rabiee & Pooyan Makvandi. (2024) Engineered (NH2)-MIL-125(Ti)/copolymer@MnFe2O4 nanocomposite for synergistic eradication of cancer cells via DOX/pCRISPR delivery. Advanced Composites and Hybrid Materials 7:1.
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Gopalakrishnan Venkatesan, Yuri Dancik, Natalene Koh, Paul Bigliardi & Giorgia Pastorin. (2023) Small Molecule Para-Phenylenediamine Analogues with Enhanced Oxidation Potential as Viable Permanent Hair Dyes. ACS Sustainable Chemistry & Engineering 11:33, pages 12355-12365.
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Vijayasankar PalaniappanKaliaperumal KarthikeyanSadhasivamohan Anusuya. (2023) Dermatological adverse effects of hair dye use: A narrative review. Indian Journal of Dermatology, Venereology and Leprology 0, pages 1-17.
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Maryam Salami, Jalal Pourahmad & Mohammad Hadi Zarei. (2023) Toxicity of para-phenylenediamine (PPD;1, 4 diaminobenzene) on isolated human lymphocytes: The key role of intracellular calcium enhancement in PPD-induced apoptosis. Toxicology and Industrial Health 39:7, pages 388-397.
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Xiaoli Chen, Tao He, Xinlu Yang, Yijing Gan, Xian Qing, Jun Wang & Yumei Huang. (2023) Analysis, environmental occurrence, fate and potential toxicity of tire wear compounds 6PPD and 6PPD-quinone. Journal of Hazardous Materials 452, pages 131245.
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Elliot Rossomme, William M. Hart-Cooper, William J. Orts, Colleen M. McMahan & Martin Head-Gordon. (2023) Computational Studies of Rubber Ozonation Explain the Effectiveness of 6PPD as an Antidegradant and the Mechanism of Its Quinone Formation. Environmental Science & Technology 57:13, pages 5216-5230.
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Sharlee L. More, Ernest S. Fung, Claire Mathis, Alexandra M. Schulte & Dana Hollins. (2023) Dermal exposure and hair dye: Assessing potential bladder cancer risk from permanent hair dye. Regulatory Toxicology and Pharmacology 138, pages 105331.
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Kyeoungsook Yun & Cheunsoon Ahn. (2023) Effect of surfactant type on the dyeability and color resistance of semi-permanent basic hair dye. Fashion and Textiles 10:1.
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Zifang Peng, Wenfen Zhang, Dan Yin, Xu Zhang, Shuo Liu, Wuduo Zhao, Jian Mao, Yanhao Zhang & Jianping Xie. (2022) Novel magnetic single-layer nano-MXene as a highly effective adsorbent and new SALDI-TOF-MS matrix for enrichment and rapid determination of p-Phenylenediamine antioxidants in water. Chemical Engineering Journal, pages 139978.
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Xiaofang Chen, Min Feng, Xiaoyi Xie, Yi Zhang, Jie Zhang & Xiupei Yang. (2022) Fe single atoms anchored on fluorine-doped ultrathin carbon nanosheets for sensitive colorimetric detection of p-phenylenediamine. Talanta 246, pages 123487.
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Xia Wang, Xi Zhao, Yannan Chen, Qingxin Wang, Hui Yang & Fei Xia. (2022) Para ‐phenylenediamine deteriorates oocyte quality by impairing mitochondrial function . Environmental Toxicology 37:7, pages 1803-1813.
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Vaishali Choudhary, Kowsalya Vellingiri, Mohammed Iqbal Thayyil & Ligy Philip. (2021) Removal of antibiotics from aqueous solutions by electrocatalytic degradation. Environmental Science: Nano 8:5, pages 1133-1176.
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Shaohua Xu, Hui Wang, Yeguo Liu, Chengfeng Zhang, Yang Xu, Feng Tian & Lin Mei. (2021) Hair chemicals may increase breast cancer risk: A meta-analysis of 210319 subjects from 14 studies. PLOS ONE 16:2, pages e0243792.
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Mark Geppert, Alexandra Schwarz, Lea Maria Stangassinger, Susanna Wenger, Lisa Maria Wienerroither, Stefanie Ess, Albert Duschl & Martin Himly. (2020) Interactions of TiO 2 Nanoparticles with Ingredients from Modern Lifestyle Products and Their Effects on Human Skin Cells . Chemical Research in Toxicology 33:5, pages 1215-1225.
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