Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 12
Submit an article Journal homepage
707
Views
15
CrossRef citations to date
0
Altmetric
General Xenobiochemistry

Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1

Guru R. ValicherlaDepartment of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd, Hyderabad, IndiaView further author information
,
Amrut MishraDepartment of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd, Hyderabad, IndiaView further author information
,
Srinivas LenkalapellyDepartment of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd, Hyderabad, IndiaView further author information
,
Bhupathi JillelaDepartment of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd, Hyderabad, IndiaView further author information
,
Femi M. FrancisDepartment of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd, Hyderabad, IndiaView further author information
,
Lakshman RajagopalanDepartment of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd, Hyderabad, IndiaView further author information
&
Pratima SrivastavaDepartment of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd, Hyderabad, IndiaCorrespondence[email protected]
View further author information
 show all
Pages 1396-1402 | Received 28 Dec 2018, Accepted 07 Feb 2019, Published online: 19 Jun 2019

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Ahmednajash Yusuf, Lemessa Oljira, Ame Mehadi & Behailu Hawulte Ayele. (2023) Integrated Disease Surveillance Response Practice and Associated Factors Among Health Professionals Working in Public Hospitals in West Hararghe Zone, Eastern Oromia, Ethiopia: Multi-Center Cross-Sectional Study. Journal of Multidisciplinary Healthcare 16, pages 1111-1126.
Read now
Jinghua Zhang, Sennan Shao, Dan Huang, Jing Zhang, Yue Dai, Zhifeng Wei & Yufeng Xia. (2021) Effect and underlying mechanism of morin on the pharmacokinetics of diclofenac sodium in rats. Xenobiotica 51:10, pages 1181-1187.
Read now

Articles from other publishers (13)

Wenkui Li, Faye Vazvaei‐Smith, Gordon Dear, Jason Boer, Filip Cuyckens, Daniela Fraier, Yuexia Liang, Ding Lu, Heidi Mangus, Patricia Moliner, Mette Lund Pedersen, Andrea A. Romeo, Douglas K. Spracklin, David S. Wagner, Serge Winter & Xiaohui (Sophia) Xu. (2024) Metabolite Bioanalysis in Drug Development: Recommendations from the IQ Consortium Metabolite Bioanalysis Working Group . Clinical Pharmacology & Therapeutics 115:5, pages 939-953.
Crossref
Raphael Nudelman, Grace Kocks, Bruno Mouton, David J. Ponting, Joerg Schlingemann, Stephanie Simon, Graham F. Smith, Andrew Teasdale & Anne-Laure Werner. (2023) The Nitrosamine “Saga”: Lessons Learned from Five Years of Scrutiny. Organic Process Research & Development 27:10, pages 1719-1735.
Crossref
David J. Ponting & Robert S. Foster. (2023) Drawing a Line: Where Might the Cohort of Concern End?. Organic Process Research & Development 27:10, pages 1703-1713.
Crossref
Fei Lin, Xinhua Lin, Xuewen Wang, Guanghui Mei, Bing Chen, Hong Yao & Lingyi Huang. (2023) Inhibitory effect of Selaginella doederleinii hieron on human cytochrome P450. Frontiers in Pharmacology 14.
Crossref
David J. Ponting, Krista L. Dobo, Michelle O. Kenyon & Amit S. Kalgutkar. (2022) Strategies for Assessing Acceptable Intakes for Novel N -Nitrosamines Derived from Active Pharmaceutical Ingredients . Journal of Medicinal Chemistry 65:23, pages 15584-15607.
Crossref
Vladimir Mishin, Diane E. Heck, Yi-Hua Jan, Jason R. Richardson & Jeffrey D. Laskin. (2022) Distinct effects of form selective cytochrome P450 inhibitors on cytochrome P450-mediated monooxygenase and hydrogen peroxide generating NADPH oxidase. Toxicology and Applied Pharmacology 455, pages 116258.
Crossref
Yujie Wu, Aiqing Qiao, Shu Lin & Lijia Chen. (2022) In vitro evaluation of the inhibition potential of echinacoside on human cytochrome P450 isozymes. BMC Complementary Medicine and Therapies 22:1.
Crossref
Lavanya Bolla, Pratima Srivastava, Velayutham Ravichandiran & Satheesh Kumar Nanjappan. (2021) Cytochrome P450 and P-gp Mediated Herb-Drug Interactions and Molecular Docking Studies of Garcinol. Membranes 11:12, pages 992.
Crossref
Guru Raghavendra Valicherla, Phillip Graebing, Junmei Zhang, Ruohui Zheng, Jeremy Nuttall, Peter Silvera & Lisa Cencia Rohan. (2021) Investigating the Contribution of Drug-Metabolizing Enzymes in Drug-Drug Interactions of Dapivirine and Miconazole. Pharmaceutics 13:12, pages 2193.
Crossref
Gang Li, Bowen Yi, Jingtong Liu, Xiaoquan Jiang, Fulu Pan, Wenning Yang, Haibo Liu, Yang Liu & Guopeng Wang. (2021) Effect of CYP3A4 Inhibitors and Inducers on Pharmacokinetics and Pharmacodynamics of Saxagliptin and Active Metabolite M2 in Humans Using Physiological-Based Pharmacokinetic Combined DPP-4 Occupancy. Frontiers in Pharmacology 12.
Crossref
Y.F. Yong, S.C. Tan, Mervyn W.O. Liew & N.S. Yaacob. (2020) Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method development for screening of potential tamoxifen-drug/herb interaction via in vitro cytochrome P450 inhibition assay. Journal of Chromatography B 1148, pages 122148.
Crossref
Yu Fen Zheng, Soo Hyeon Bae, Zhouchi Huang, Soon Uk Chae, Seong Jun Jo, Hyung Joon Shim, Chae Bin Lee, Doyun Kim, Hunseung Yoo & Soo Kyung Bae. (2020) Lack of Correlation between In Vitro and In Vivo Studies on the Inhibitory Effects of (‒)-Sophoranone on CYP2C9 Is Attributable to Low Oral Absorption and Extensive Plasma Protein Binding of (‒)-Sophoranone. Pharmaceutics 12:4, pages 328.
Crossref
Chuang Lu & Li Di. (2020) In vitro and in vivo methods to assess pharmacokinetic drug– drug interactions in drug discovery and development . Biopharmaceutics & Drug Disposition 41:1-2, pages 3-31.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.