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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 4
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General Xenobiochemistry

Bergamottin can be used to assess CYP3A-mediated intestinal first-pass metabolism without affecting P-glycoprotein-mediated efflux in rats

Kei SuzukiExploratory Research Laboratories, Drug Research Department, TOA EIYO LTD., Fukushima, Japan; Correspondence[email protected]
,
Kazuhiro TaniyamaExploratory Research Laboratories, Drug Research Department, TOA EIYO LTD., Fukushima, Japan;
,
Takao AoyamaFaculty of Pharmaceutical Science, Tokyo University of Science, Chiba, Japan
&
Yoshiaki WatanabeExploratory Research Laboratories, Drug Research Department, TOA EIYO LTD., Fukushima, Japan;
Pages 401-407 | Received 26 Mar 2019, Accepted 12 Jul 2019, Published online: 01 Aug 2019

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Xinjuan Zhang, Jinyao Guo, Jin Li, Chen Chen & Guijun Su. (2022) Pharmacokinetics and pharmacodynamic interaction of bergamottin with atorvastatin in rats. Xenobiotica 52:5, pages 463-467.
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Junmei Chen, Jinman Liu, Yueyue Huang, Ruoyu Li, Cuiru Ma, Beiping Zhang, Fanchang Wu, Wenqian Yu, Xue Zuo, Yong Liang & Qi Wang. (2021) Insights into oral bioavailability enhancement of therapeutic herbal constituents by cytochrome P450 3A inhibition. Drug Metabolism Reviews 53:4, pages 491-507.
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Articles from other publishers (3)

Yusuke Tanaka, Kazuhiro Ito, Takanori Kurakazu & Satoshi Kasaoka. (2023) Separate Evaluation of Fraction Absorbed and Intestinal Availability after Oral Administration of Drugs Based on the Measurement of Portal and Systemic Plasma Concentrations and Luminal Concentration. Molecular Pharmaceutics 20:4, pages 1933-1941.
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Ebru Yazıcı, Elif Şahin, Elif Alvuroğlu, Esin Yuluğ & Ahmet Menteşe. (2023) Bergamottin reduces liver damage by suppressing inflammation, endoplasmic reticulum and oxidative stress in cafeteria diet-fed mice. Food Bioscience 52, pages 102371.
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Camila Juliana Domínguez, Guillermo Nicolás Tocchetti, Juan Pablo Rigalli & Aldo Domingo Mottino. (2021) Acute regulation of apical ABC transporters in the gut. Potential influence on drug bioavailability. Pharmacological Research 163, pages 105251.
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