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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 5
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General Xenobiochemistry

A hybrid model to evaluate the impact of active uptake transport on hepatic distribution of atorvastatin in rats

Priyanka KulkarniDepartment of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA, USACorrespondence[email protected]
,
Ken KorzekwaDepartment of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA, USA
&
Swati NagarDepartment of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA, USA
Pages 536-544 | Received 02 Aug 2019, Accepted 13 Sep 2019, Published online: 01 Oct 2019

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Jaydeep Yadav, Mehdi El Hassani, Jasleen Sodhi, Volker M. Lauschke, Jessica H. Hartman & Laura E. Russell. (2021) Recent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data. Drug Metabolism Reviews 53:2, pages 207-233.
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Articles from other publishers (4)

Chan Bae, Gujin Chung & Suk-Jae Chung. (2023) Prediction of the Time to Reach Equilibrium for Improved Estimation of the Unbound Fraction of Compounds in Equilibrium Dialysis Using kinetic Modeling. Journal of Pharmaceutical Sciences.
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Ken Korzekwa, Jaydeep Yadav & Swati Nagar. (2022) Using partition analysis as a facile method to derive net clearances. Clinical and Translational Science 15:8, pages 1867-1879.
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Mo’tasem M. Alsmadi, Nour M. AL-Daoud, Rana M. Obaidat & Niazy A. Abu-Farsakh. (2022) Enhancing Atorvastatin In Vivo Oral Bioavailability in the Presence of Inflammatory Bowel Disease and Irritable Bowel Syndrome Using Supercritical Fluid Technology Guided by wbPBPK Modeling in Rat and Human. AAPS PharmSciTech 23:5.
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Joe Bentz & Harma Ellens. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 737 763 .

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