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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 8
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Animal Pharmacokinetics and Metabolism

Withanolide a penetrates brain via intra-nasal administration and exerts neuroprotection in cerebral ischemia reperfusion injury in mice

Sumedha MukherjeeElectrophysiology Lab, School of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi, India; ORCID Iconhttps://orcid.org/0000-0001-6625-815X
ORCID Icon,
Gaurav KumarElectrophysiology Lab, School of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi, India; ;School of Biological and Biomedical Sciences, Galgotias University, Gr. Noida, IndiaORCID Iconhttps://orcid.org/0000-0003-2823-8419
ORCID Icon &
Ranjana PatnaikElectrophysiology Lab, School of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi, India; ;School of Biological and Biomedical Sciences, Galgotias University, Gr. Noida, IndiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8131-177X
ORCID Icon
Pages 957-966 | Received 03 Nov 2019, Accepted 22 Dec 2019, Published online: 13 Jan 2020

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Yallappa B. Saunshi, Corbon Godfrey David, Heartwin A. Pushpadass, Magdaline Eljeeva Emerald Franklin, Vaibhav Bhagwan Awachat & Veeranna R. Kadakol. (2023) Characterization of withanolides and bacoside A-loaded proniosomes: effect on oxidative stress and survival under hypergravity in rodent model. Drug Development and Industrial Pharmacy 49:12, pages 748-758.
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Vivek K Kashyap, Anupam Dhasmana, Murali M Yallapu, Subhash C Chauhan & Meena Jaggi. (2020) Withania somnifera as a potential future drug molecule for COVID-19. Future Drug Discovery 2:4.
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Ambarish Kumar Sinha, Kajal Dahiya & Gaurav Kumar. (2023) Identification of Withanolide G as a Potential Inhibitor of Rho-associated Kinase-2 Catalytic Domain to Confer Neuroprotection in Ischemic Stroke. Letters in Drug Design & Discovery 20:7, pages 845-853.
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Paulina Mikulska, Marta Malinowska, Miłosz Ignacyk, Paweł Szustowski, Joanna Nowak, Karolina Pesta, Monika Szeląg, Damian Szklanny, Eliza Judasz, Gabriela Kaczmarek, Ovinuchi Prince Ejiohuo, Magdalena Paczkowska-Walendowska, Anna Gościniak & Judyta Cielecka-Piontek. (2023) Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review. Pharmaceutics 15:4, pages 1057.
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Suramya Malhotra & Rajat Sandhir. 2023. Ayurvedic Herbal Preparations in Neurological Disorders. Ayurvedic Herbal Preparations in Neurological Disorders 113 140 .
Manali Singh, Kuldeep Jayant, Dipti Singh, Shivani Bhutani, Nitesh Kumar Poddar, Anis Ahmad Chaudhary, Salah-Ud-Din Khan, Mohd Adnan, Arif Jamal Siddiqui, Md Imtaiyaz Hassan, Faez Iqbal Khan, Dakun Lai & Shahanavaj Khan. (2022) Withania somnifera (L.) Dunal (Ashwagandha) for the possible therapeutics and clinical management of SARS-CoV-2 infection: Plant-based drug discovery and targeted therapy. Frontiers in Cellular and Infection Microbiology 12.
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Kakarla Ramakrishna, Shreyans K. Jain & Sairam Krishnamurthy. (2022) Pharmacokinetic and Pharmacodynamic Properties of Indole-3-carbinol in Experimental Focal Ischemic Injury. European Journal of Drug Metabolism and Pharmacokinetics 47:4, pages 593-605.
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Mirtha Navarro-Hoyos, Elizabeth Arnáez-Serrano, María Isabel Quirós-Fallas, Felipe Vargas-Huertas, Krissia Wilhelm-Romero, Felipe Vásquez-Castro, Diego Alvarado-Corella & Andrés Sánchez-Kopper. (2022) QTOF-ESI MS Characterization and Antioxidant Activity of Physalis peruviana L. (Cape Gooseberry) Husks and Fruits from Costa Rica. Molecules 27:13, pages 4238.
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Jia-Tong Wu, Yan Liu, Yi-Kai Jiang, Si-Yi Wang, Chen-Yu Jiang, Adnan Mohammed Algradi, Juan Pan, Wei Guan, Hai-Xue Kuang & Bing-You Yang. (2022) Datinolides E-I, five new withanolides with anti-inflammatory activity from the leaves of Datura inoxia Mill. Fitoterapia 159, pages 105204.
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Kamsala Venkata Ratnam, Lepakshi Md. Bhakshu & Rudraraju Reddy Venkata Raju. 2022. Role of Nutrients in Neurological Disorders. Role of Nutrients in Neurological Disorders 303 317 .
Ashish Kumar, Arpita Konar, Sukant Garg, Sunil C. Kaul & Renu Wadhwa. (2021) Experimental evidence and mechanism of action of some popular neuro-nutraceutical herbs. Neurochemistry International 149, pages 105124.
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Akash Saggam, Kirti Limgaokar, Swapnil Borse, Preeti Chavan-Gautam, Santosh Dixit, Girish Tillu & Bhushan Patwardhan. (2021) Withania somnifera (L.) Dunal: Opportunity for Clinical Repurposing in COVID-19 Management. Frontiers in Pharmacology 12.
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