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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 7
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Animal Pharmacokinetics and Metabolism

Effect of compromised liver function and acute kidney injury on the pharmacokinetics of thymoquinone in a rat model

Khalid M. AlkharfyDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Correspondence[email protected]
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,
Fahad A. AliDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; View further author information
,
Mohammad A. AlkharfyKing Saud Medical City, Riyadh, Saudi Arabia; View further author information
,
Basit L. JanDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; View further author information
,
Mohammad RaishDepartment Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaView further author information
,
Saeed AlqahtaniDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; View further author information
&
Ajaz AhmadDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Correspondence[email protected]
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Pages 858-862 | Received 09 Feb 2020, Accepted 17 Mar 2020, Published online: 27 Mar 2020

Citations (7)

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Read on this site (2)

Osama A Badary, Marwa S Hamza & Rajiv Tikamdas. (2021) Thymoquinone: A Promising Natural Compound with Potential Benefits for COVID-19 Prevention and Cure. Drug Design, Development and Therapy 15, pages 1819-1833.
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Jaydeep Yadav, Mehdi El Hassani, Jasleen Sodhi, Volker M. Lauschke, Jessica H. Hartman & Laura E. Russell. (2021) Recent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data. Drug Metabolism Reviews 53:2, pages 207-233.
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Articles from other publishers (5)

Mouna Selmi, Abir Salek, Mahassen Barboura, Leila Njim, Amine Trabelsi, Aida Lahmar, Nolwenn Lautram, Emilie Roger, Tarek Baati & Leila chekir Ghedira. (2023) Thymoquinone-loaded lipid nanocapsules with promising anticancer activity for colorectal cancer. Nanoscale Advances 5:19, pages 5390-5398.
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Fangle Liu, Yun Zeng, Pengyu Dai, Kaiwen Huang, Kaihui Zhang, Tao Tao, Meiqi Wang, Chenchen Zhu & Chaozhan Lin. (2022) Comparative Pharmacokinetics of Three Bioactive Diterpenoids of Rabdosia serra Extract in Normal and Con A-Induced Liver Injury Rats Using UPLC-MS/MS. Frontiers in Pharmacology 13.
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Seyed Parsa Eftekhar, Sohrab Kazemi & Ali Akbar Moghadamnia. (2022) Effect of thymoquinone on pharmacokinetics of 5-fluorouracil in rats and its effect on human cell line in vitro . Human & Experimental Toxicology 41, pages 096032712211454.
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Mohamed A. El‐Missiry, Ahmed Fekri, Lakshmi A. Kesar & Azza I. Othman. (2020) Polyphenols are potential nutritional adjuvants for targeting COVID ‐19 . Phytotherapy Research 35:6, pages 2879-2889.
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Abhishek Gour, Ashish Dogra, Sumit Sharma, Priya Wazir & Utpal Nandi. (2021) Effect of Disease State on the Pharmacokinetics of Bedaquiline in Renal-Impaired and Diabetic Rats. ACS Omega 6:10, pages 6934-6941.
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