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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 11
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General Xenobiochemistry

First dose in neonates: pharmacokinetic bridging study from juvenile mice to neonates for drugs metabolized by CYP3A

Pan-Pan Yea Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China;b Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University, Jinan, ChinaView further author information
,
Yi Zhengc Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ChinaView further author information
,
Bin Duc Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ChinaView further author information
,
Xi-Ting Liuc Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ChinaView further author information
,
Bo-Hao Tangc Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ChinaView further author information
,
Min Kanc Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ChinaView further author information
,
Yue Zhouc Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ChinaView further author information
,
Guo-Xiang Haoc Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ChinaView further author information
,
Xin Huangb Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University, Jinan, ChinaView further author information
,
Le-Qun Sub Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University, Jinan, ChinaView further author information
,
Wen-Qi Wangd Clinical Research Center, The First Affiliated Hospital of Shandong First Medical University, Jinan, ChinaView further author information
,
Feng Yua Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, ChinaCorrespondence[email protected]
View further author information
&
Wei Zhaob Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University, Jinan, China;c Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China;d Clinical Research Center, The First Affiliated Hospital of Shandong First Medical University, Jinan, China;e Department of Pediatrics, The First Affiliated Hospital of Shandong First Medical University, Jinan, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1830-338XView further author information
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Pages 1275-1284 | Received 12 Mar 2020, Accepted 09 May 2020, Published online: 25 May 2020

Citations (3)

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Read on this site (1)

Jingjing Ye, Youwei Bi & Naitee Ting. (2023) How to select the initial dose for a pediatric study?. Journal of Biopharmaceutical Statistics 33:6, pages 844-858.
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Articles from other publishers (2)

Kefei Wang, Kun Jiang, Xiaoyi Wei, Yulan Li, Tiejie Wang & Yang Song. (2021) Physiologically Based Pharmacokinetic Models Are Effective Support for Pediatric Drug Development. AAPS PharmSciTech 22:6.
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Youwei Bi, Jiang Liu, Fang Li, Jingyu Yu, Atul Bhattaram, Michael Bewernitz, Ruo‐jing Li, Jihye Ahn, Justin Earp, Lian Ma, Luning Zhuang, Yuching Yang, Xinyuan Zhang, Hao Zhu & Yaning Wang. (2021) Model‐Informed Drug Development in Pediatric Dose Selection. The Journal of Clinical Pharmacology 61:S1.
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