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Xenobiotica
the fate of foreign compounds in biological systems
Volume 51, 2021 - Issue 1
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General Xenobiochemistry

Understanding metabolism related differences in ocular efficacy of MGV354

Jennifer L. Dumouchela Pharmacokinetic Sciences, Novartis Institutes for BioMedical Research, Cambridge, MA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9954-2149
ORCID Icon,
Upendra A. Argikara Pharmacokinetic Sciences, Novartis Institutes for BioMedical Research, Cambridge, MA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0939-0813
ORCID Icon,
Christopher M. Adamsb Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0002-5246-884X
ORCID Icon,
Ganesh Prasannac Ophthalmology, Novartis Institutes for BioMedical Research, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0001-6420-270X
ORCID Icon,
Takeru Eharab Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0002-4889-204X
ORCID Icon,
Sean Kima Pharmacokinetic Sciences, Novartis Institutes for BioMedical Research, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0003-1184-8771
ORCID Icon,
Chris Breena Pharmacokinetic Sciences, Novartis Institutes for BioMedical Research, Cambridge, MA, USA
&
Muneto Mogib Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USA
 show all
Pages 5-14 | Received 05 Jun 2020, Accepted 09 Jul 2020, Published online: 21 Jul 2020

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Mario Öeren, Peter A. Hunt, Charlotte E. Wharrick, Hamed Tabatabaei Ghomi & Matthew D. Segall. Predicting routes of phase I and II metabolism based on quantum mechanics and machine learning. Xenobiotica 0:0, pages 1-49.
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Articles from other publishers (1)

Bianca Saveria Fioretto, Irene Rosa, Elena Andreucci, Rita Mencucci, Mirca Marini, Eloisa Romano & Mirko Manetti. (2024) Pharmacological Stimulation of Soluble Guanylate Cyclase Counteracts the Profibrotic Activation of Human Conjunctival Fibroblasts. Cells 13:4, pages 360.
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