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Xenobiotica
the fate of foreign compounds in biological systems
Volume 51, 2021 - Issue 9
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Molecular Toxicology

Hepatotoxic effect of tramadol and O-desmethyltramadol in HepG2 cells and potential role of PI3K/AKT/mTOR

Manar A. Helmya Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Mansoura University, Mansoura, EgyptCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-6075-8655
ORCID Icon,
Hussein Abdelaziz Abdallab Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt;c Department of Clinical Biochemistry and Molecular Medicine, Faculty of Medicine, Taibah University, Medina, Saudi Arabia
,
Heba Allah Abd El Rahmana Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Mansoura University, Mansoura, EgyptORCID Iconhttps://orcid.org/0000-0002-1566-5887
ORCID Icon &
Dalia Alsaied Moustafa Ahmeda Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Pages 1029-1037 | Received 29 Apr 2021, Accepted 26 Jul 2021, Published online: 09 Aug 2021

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Houman Kamranian, Hadi Asoudeh, Roya Kamrani Sharif, Fereshteh Taheri, A. Wallace Hayes, Mina Gholami, Ahmad Alavi & Majid Motaghinejad. (2023) Neuroprotective potential of trimetazidine against tramadol-induced neurotoxicity: role of PI3K/Akt/mTOR signaling pathways. Toxicology Mechanisms and Methods 33:7, pages 607-623.
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Tülay Ceren Ölmeztürk Karakurt, Nurhan Eren, Faruk Subaşı, Ufuk Kuyrukluyıldız, Taha Abdulkadir Çoban, Halis Süleyman & Behzad Mokhtare. (2023) Effects of taxifolin on tramadol-induced oxidative and inflammatory liver injury in rats: an experimental study. Drug and Chemical Toxicology 0:0, pages 1-6.
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Tanju Kapagan, Nilufer Bulut & Gokmen Umut Erdem. (2023) Polypharmacy and drug-drug interactions in metastatic breast cancer patients receiving cyclin-dependent kinase (CDK) 4/6 inhibitors. Journal of Oncology Pharmacy Practice.
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Justyna Szulc, Joanna Nizioł, Tomasz Ruman, Anna Kuźniar, Adriana Nowak, Małgorzata Okrasa, Ireneusz Nowak, Bogumiła Szponar & Sławomir Kuberski. (2023) Biological and chemical contamination of illegal, uncontrolled refuse storage areas in Poland. Environmental Research 228, pages 115825.
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