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Xenobiotica
the fate of foreign compounds in biological systems
Volume 52, 2022 - Issue 3
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General Xenobiochemistry

Comparison of mouse and human cytochrome P450 mediated-drug metabolising activities in hepatic and extrahepatic microsomes

Shotaro Ueharaa Laboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, JapanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1359-8828View further author information
ORCID Icon,
Norie Murayamab Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, JapanView further author information
,
Yuichiro Higuchia Laboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, JapanView further author information
,
Nao Yonedaa Laboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, JapanView further author information
,
Hiroshi Yamazakib Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, JapanORCID Iconhttps://orcid.org/0000-0002-1068-4261View further author information
ORCID Icon &
Hiroshi Suemizua Laboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, JapanORCID Iconhttps://orcid.org/0000-0002-3706-2454View further author information
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Pages 229-239 | Received 12 Mar 2022, Accepted 12 Apr 2022, Published online: 26 Apr 2022

Citations (4)

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Yasuhiro Uno, Shotaro Uehara, Genki Ushirozako, Tatsunori Masatani & Hiroshi Yamazaki. (2023) Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver. Xenobiotica 53:10-11, pages 581-586.
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Articles from other publishers (3)

Jonghwa Lee, Jessica L. Beers, Raeanne M. Geffert & Klarissa D. Jackson. (2024) A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment. Biomolecules 14:1, pages 99.
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Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Hiroaki Kato, Hiroshi Yamazaki & Hiroshi Suemizu. (2023) The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers. Drug Metabolism and Disposition 51:4, pages 480-491.
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Cai Zhang, Song Fan, Jin‐Quan Zhao, Yan Jiang, Jia‐Xing Sun & Hui‐Jun Li. (2022) Transcriptomics and metabolomics reveal the role of CYP1A2 in psoralen/isopsoralen‐induced metabolic activation and hepatotoxicity . Phytotherapy Research 37:1, pages 163-180.
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