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Xenobiotica
the fate of foreign compounds in biological systems
Volume 52, 2022 - Issue 8: 50th year of the DMDG
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Research Articles

The in vitro metabolism and in vivo pharmacokinetics of the bacterial β-glucuronidase inhibitor UNC10201652

Anna Kerinsa Cyprotex Discovery, Macclesfield, UKORCID Iconhttps://orcid.org/0000-0001-7851-7542
ORCID Icon,
Marta Koszyczareka Cyprotex Discovery, Macclesfield, UKORCID Iconhttps://orcid.org/0000-0003-4322-3338
ORCID Icon,
Caroline Smitha Cyprotex Discovery, Macclesfield, UK
,
Phil Butlera Cyprotex Discovery, Macclesfield, UKORCID Iconhttps://orcid.org/0000-0003-0449-4987
ORCID Icon,
Rob Rileya Cyprotex Discovery, Macclesfield, UK
,
Vamsi Madgulab DMPK and Toxicology, Sai Life Sciences Limited, Hyderabad, India
,
Nilkanth Naikb DMPK and Toxicology, Sai Life Sciences Limited, Hyderabad, India
,
Matthew R. Redinboc Departments of Chemistry, Biochemistry & Biophysics, and Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAORCID Iconhttps://orcid.org/0000-0003-0814-5346
ORCID Icon &
Ian D. Wilsond Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UKCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8558-7394
ORCID Icon show all
Pages 904-915 | Received 29 Jul 2022, Accepted 21 Sep 2022, Published online: 20 Dec 2022

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Shuai Wang, Upendra A. Argikar, Lionel Cheruzel, Sungjoon Cho, Rachel D. Crouch, Deepika Dhaware, Carley J. S. Heck, Kevin M. Johnson, Amit S. Kalgutkar, Lloyd King, Joyce Liu, Bin Ma, Hlaing Maw, Grover P. Miller, Herana Kamal Seneviratne, Ryan H. Takahashi, Cong Wei & S. Cyrus Khojasteh. (2023) Bioactivation and reactivity research advances – 2022 year in review‡. Drug Metabolism Reviews 55:4, pages 267-300.
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