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Xenobiotica
the fate of foreign compounds in biological systems
Volume 52, 2022 - Issue 8: 50th year of the DMDG
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Application of physiologically based pharmacokinetic models for therapeutic proteins and other novel modalities

Rachel H. RoseCertara UK Limited, Simcyp Division, Sheffield, UKCorrespondence[email protected]
,
Armin SeppCertara UK Limited, Simcyp Division, Sheffield, UK
,
Felix StaderCertara UK Limited, Simcyp Division, Sheffield, UK
,
Katherine L. GillCertara UK Limited, Simcyp Division, Sheffield, UK
,
Cong LiuCertara UK Limited, Simcyp Division, Sheffield, UK
&
Iain GardnerCertara UK Limited, Simcyp Division, Sheffield, UK
Pages 840-854 | Received 09 Aug 2022, Accepted 04 Oct 2022, Published online: 20 Dec 2022

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Xiang Gao, John K. Diep, Daniel A. Norris, Rosie Z. Yu & Richard S. Geary. (2023) Predicting the pharmacokinetics and pharmacodynamics of antisense oligonucleotides: an overview of various approaches and opportunities for PBPK/PD modelling. Expert Opinion on Drug Metabolism & Toxicology 19:12, pages 979-990.
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Simon Taylor, Jamie Henshall, Kevin Beaumont, Steve Hood, Barry Jones, Ian Wilson & Dennis Smith. (2022) The 50th anniversary of the DMDG. Xenobiotica 52:8, pages 767-769.
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