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Xenobiotica
the fate of foreign compounds in biological systems
Volume 52, 2022 - Issue 9-11
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General Xenobiochemistry

A comprehensive analysis of six forms of cytochrome P450 2C (CYP2C) in pigs

Yasuhiro Unoa Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima-city, JapanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9040-1681View further author information
ORCID Icon,
Saho Morikunib Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, JapanView further author information
,
Mitsuya Shiraishia Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima-city, JapanView further author information
,
Atsushi Asanoa Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima-city, JapanView further author information
,
Hiroaki Kawaguchic School of Veterinary Medicine, Kitasato University, Towada, JapanView further author information
,
Norie Murayamab Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, JapanView further author information
&
Hiroshi Yamazakib Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, JapanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1068-4261View further author information
ORCID Icon show all
Pages 963-972 | Received 25 Oct 2022, Accepted 12 Nov 2022, Published online: 17 Nov 2022

Citations (6)

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Yasuhiro Uno, Saho Morikuni, Norie Murayama & Hiroshi Yamazaki. (2023) 2-Oxidation, 3-methyl hydroxylation, and 6-hydroxylation of skatole, a contributor to the odour of boar-tainted pork meat, mediated by porcine liver microsomal cytochromes P450 1A2, 2A19, 2E1, and 3A22. Xenobiotica 53:1, pages 60-65.
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Articles from other publishers (5)

Yasuhiro Uno, Makiko Shimizu & Hiroshi Yamazaki. (2024) A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models. Biochemical Pharmacology, pages 116124.
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Yasuhiro Uno, Yuhki Minami, Kyoko Tsukiyama-Kohara, Norie Murayama & Hiroshi Yamazaki. (2023) Identification of cytochrome P450 2C18 and 2C76 in tree shrews: P450 2C18 effectively oxidizes typical human P450 2C9/2C19 chiral substrates warfarin and omeprazole with less stereoselectivity. Biochemical Pharmacology, pages 115990.
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Yasuhiro Uno, Saho Morikuni, Mitsuya Shiraishi, Atsushi Asano, Norie Murayama & Hiroshi Yamazaki. (2023) Novel Cytochrome P450 2C94 Functionally Metabolizes Diclofenac and Omeprazole in Dogs. Drug Metabolism and Disposition 51:5, pages 637-644.
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Yasuhiro Uno, Shiori Jikuya, Yutaro Noda, Asuka Oguchi, Norie Murayama, Hiroaki Kawaguchi, Kyoko Tsukiyama-Kohara & Hiroshi Yamazaki. (2023) Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 267, pages 109579.
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Roua Gabriela Popescu, George Cătălin Marinescu, Andreea Luminița Rădulescu, Daniela Eliza Marin, Ionelia Țăranu & Anca Dinischiotu. (2023) Natural Antioxidant By-Product Mixture Counteracts the Effects of Aflatoxin B1 and Ochratoxin A Exposure of Piglets after Weaning: A Proteomic Survey on Liver Microsomal Fraction. Toxins 15:4, pages 299.
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