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Xenobiotica
the fate of foreign compounds in biological systems
Volume 27, 1997 - Issue 9
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Research Article

Examination of metabolic pathways and identification of human liver cytochrome P450 isozymes responsible for the metabolism of barnidipine, a calcium channel blocker

T. TERAMURA* Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co. Ltd 1-8, Azusawa 1-chome, Itabashi-ku, Tokyo 174, Japan ADME, Clinical Pharmacology Department, Yamanouchi Europe B.V., PO Box 108, 2350 AC Leiderdorp, The Netherlands
,
Y. FUKUNAGA Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co. Ltd 1-8, Azusawa 1-chome, Itabashi-ku, Tokyo 174, Japan ADME, Clinical Pharmacology Department, Yamanouchi Europe B.V., PO Box 108, 2350 AC Leiderdorp, The Netherlands
,
E. J. VAN HOOGDALEM Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co. Ltd 1-8, Azusawa 1-chome, Itabashi-ku, Tokyo 174, Japan ADME, Clinical Pharmacology Department, Yamanouchi Europe B.V., PO Box 108, 2350 AC Leiderdorp, The Netherlands
,
T. WATANABE Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co. Ltd 1-8, Azusawa 1-chome, Itabashi-ku, Tokyo 174, Japan ADME, Clinical Pharmacology Department, Yamanouchi Europe B.V., PO Box 108, 2350 AC Leiderdorp, The Netherlands
&
S. HIGUCHI Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co. Ltd 1-8, Azusawa 1-chome, Itabashi-ku, Tokyo 174, Japan ADME, Clinical Pharmacology Department, Yamanouchi Europe B.V., PO Box 108, 2350 AC Leiderdorp, The Netherlands
Pages 885-900 | Published online: 22 Sep 2008

Citations (9)

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Read on this site (2)

Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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S. Ozawa, K. Ohta, A. Miyajima, H. Kurebayashi, M. Sunouchi, M. Shimizu, N. Murayama, Y. Matsumoto, M. Fukuoka & Y. Ohno. (2000) Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1. Xenobiotica 30:10, pages 1005-1017.
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Articles from other publishers (7)

Ruina Gao. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 4 .
Shayne Cox GadEugene G. Hrycay & Stelvio M. Bandiera. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu & Jae-Gook Shin. (2007) Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes. Drug Metabolism and Disposition 35:9, pages 1518-1524.
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W Zhu, T Li, C Ni, H Liu, L Fang, M Shang, T Kikkawa, H Katoh & M Yamamoto. (2016) Comparative Study of Barnidipine and Felodipine in Chinese Patients with Essential Hypertension. Journal of International Medical Research 34:4, pages 406-412.
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Toshiro Niwa, Shinji Honda, Kiyoharu Shirakawa, Yasushi Imamura, Sadayuki Osaki & Akira Takagi. (2006) Drug interaction of fluvoxamine, a selective serotonin reuptake inhibitor. Folia Pharmacologica Japonica 128:2, pages 93-103.
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M. Teresa Donato & Jos?? V. Castell. (2003) Strategies and Molecular Probes to Investigate the Role of Cytochrome P450 in Drug Metabolism. Clinical Pharmacokinetics 42:2, pages 153-178.
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Toshiharu Sakai, Toshio Teramura, Hideaki Okamiya & Osamu Inagaki. (2007) A Review on Barnidipine: A Novel Calcium Antagonist. Cardiovascular Drug Reviews 15:4, pages 273-290.
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