Citations (40)
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David F.V. Lewis & Maurice Dickins. (2001) Quantitative Structure-Activity Relationships (QSARs) Within Series of Inhibitors for Mammalian Cytochromes P450 (CYPs). Journal of Enzyme Inhibition 16:4, pages 321-330.
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DAVID F. V. LEWIS. (1999) FRONTIER ORBITALS IN CHEMICAL AND BIOLOGICAL ACTIVITY: QUANTITATIVE RELATIONSHIPS AND MECHANISTIC IMPLICATIONS*. Drug Metabolism Reviews 31:3, pages 755-816.
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SEAN EKINS & STEVEN A. WRIGHTON. (1999) THE ROLE OF CYP2B6 IN HUMAN XENOBIOTIC METABOLISM*. Drug Metabolism Reviews 31:3, pages 719-754.
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D. F. V. Lewis, C. Ioannides & D. V. Parke. (1998) An Improved and Updated Version of the Compact Procedure for the Evaluation of P450-Mediated Chemical Activation. Drug Metabolism Reviews 30:4, pages 709-737.
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Articles from other publishers (36)
Ethan D. Angle & Philip M. Cox. (2023) Multidisciplinary Insights into the Structure–Function Relationship of the CYP2B6 Active Site. Drug Metabolism and Disposition 51:3, pages 369-384.
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So SHINYA, Yared Beyene YOHANNES, Yoshinori IKENAKA, Shouta MM NAKAYAMA, Mayumi ISHIZUKA & Shoichi FUJITA. (2022) Characteristics of cytochrome P450-dependent metabolism in the liver of the wild raccoon, <i>Procyon lotor</i>. Journal of Veterinary Medical Science 84:12, pages 1665-1672.
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Michele M. Skopec, James R. Halpert & M. Denise Dearing. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary
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Immaculate M. Langmia, Katja S. Just, Sabrina Yamoune, Jürgen Brockmöller, Collen Masimirembwa & Julia C. Stingl. (2021) CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy. Frontiers in Genetics 12.
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M.D. Chanyshev, N.I. Kosorotikov, S.E. Titov, N.N. Kolesnikov & L.F. Gulyaeva. (2014) Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs. Life Sciences 103:2, pages 95-100.
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Michele M. Skopec, Jael R. Malenke, James R. Halpert & M. Denise Dearing. (2013)
An In Vivo Assay for Elucidating the Importance of Cytochromes P450 for the Ability of a Wild Mammalian Herbivore (
Neotoma lepida
) to Consume Toxic Plants
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Dan Yao, Xiaolei Shi, Lei Wang, Blake A. Gosnell & Chi Chen. (2013) Characterization of Differential Cocaine Metabolism in Mouse and Rat through Metabolomics-Guided Metabolite Profiling. Drug Metabolism and Disposition 41:1, pages 79-88.
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M. Denise Dearing. (2012) Temperature-dependent toxicity in mammals with implications for herbivores: a review. Journal of Comparative Physiology B 183:1, pages 43-50.
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Jeferson Luis Franco, Rafael Trevisan, Thais Posser, Daniela B.B. Trivella, Roberto Hoppe, Juliana Martins Rosa, Daniel Fernandes Dinslaken, Helena Decker, Carla Inês Tasca, Rodrigo Bainy Leal, Maria Risoleta Freire Marques, Afonso Celso Dias Bainy & Alcir Luiz Dafre. (2010) Biochemical alterations in caged Nile tilapia Oreochromis niloticus. Ecotoxicology and Environmental Safety 73:5, pages 864-872.
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Azra Bozcaarmutlu & Emel Arinç. (2008)
Purification of CYP2B‐like protein from feral leaping mullet (
Liza saliens
) liver microsomes and its biocatalytic, molecular, and immunological characterization
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M.D. Dearing, M.M. Skopec & M.J. Bastiani. (2006) Detoxification rates of wild herbivorous woodrats (Neotoma). Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 145:4, pages 419-422.
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Peter Hlavica. (2006) Functional interaction of nitrogenous organic bases with cytochrome P450: A critical assessment and update of substrate features and predicted key active-site elements steering the access, binding, and orientation of amines. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1764:4, pages 645-670.
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David F.V. Lewis, Brian G. Lake, Yuko Ito & Pavel Anzenbacher. (2006) QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS (QSARs) WITHIN CYTOCHROMES P450 2B (CYP2B) SUBFAMILY ENZYMES: THE IMPORTANCE OF LIPOPHILICITY FOR BINDING AND METABOLISM. Drug Metabolism and Drug Interactions 21:3-4.
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Carol A. Kemp, Jean-Didier Maréchal & Michael J. Sutcliffe. (2005) Progress in cytochrome P450 active site modeling. Archives of Biochemistry and Biophysics 433:2, pages 361-368.
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Melissa A McKinney, Augustine Arukwe, Sylvain De Guise, Daniel Martineau, Pierre Béland, André Dallaire, Stéphane Lair, Michel Lebeuf & Robert J Letcher. (2004) Characterization and profiling of hepatic cytochromes P450 and phase II xenobiotic-metabolizing enzymes in beluga whales (Delphinapterus leucas) from the St. Lawrence River Estuary and the Canadian Arctic. Aquatic Toxicology 69:1, pages 35-49.
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Chong-Sheng Chen, Jack T. Lin, Kendrick A. Goss, You-ai He, James R. Halpert & David J. Waxman. (2004) Activation of the Anticancer Prodrugs Cyclophosphamide and Ifosfamide: Identification of Cytochrome P450 2B Enzymes and Site-Specific Mutants with Improved Enzyme Kinetics. Molecular Pharmacology 65:5, pages 1278-1285.
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Hsia-Lien Lin, Haoming Zhang, Lucy Waskell & Paul F. Hollenberg. (2003) Threonine-205 in the F Helix of P450 2B1 Contributes to Androgen 16β-Hydroxylation Activity and Mechanism-Based Inactivation. Journal of Pharmacology and Experimental Therapeutics 306:2, pages 744-751.
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David F.V. Lewis. (2002) Modelling human cytochromes P450 involved in drug metabolism from the CYP2C5 crystallographic template. Journal of Inorganic Biochemistry 91:4, pages 502-514.
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Timothy H. Bayburt & Stephen G. Sligar. (2002) Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks. Proceedings of the National Academy of Sciences 99:10, pages 6725-6730.
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Stewart B Kirton, Carol A Baxter & Michael J Sutcliffe. (2002) Comparative modelling of cytochromes P450. Advanced Drug Delivery Reviews 54:3, pages 385-406.
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Gaston Hui Bon Hoa, Mark A McLean & Stephen G Sligar. (2002) High pressure, a tool for exploring heme protein active sites. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1595:1-2, pages 297-308.
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Shigeyuki Kitamura, Yuri Shimizu, Yuko Shiraga, Mayumi Yoshida, Kazumi Sugihara & Shigeru Ohta. (2002)
Reductive Metabolism of
p
,
p
′-DDT and
o
,
p
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B. Oesch-Bartlomowicz & F. Oesch. (2002) Fast Regulation of Cytochrome P450 Activities by Phosphorylation and Consequences for Drug Metabolism and Toxicity. Biological Chemistry 383:10.
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Emily E. Scott, Margit Spatzenegger & James R. Halpert. (2001) A Truncation of 2B Subfamily Cytochromes P450 Yields Increased Expression Levels, Increased Solubility, and Decreased Aggregation While Retaining Function. Archives of Biochemistry and Biophysics 395:1, pages 57-68.
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Peter Hlavica & David F. V. Lewis. (2008) Allosteric phenomena in cytochrome P450‐catalyzed monooxygenations. European Journal of Biochemistry 268:18, pages 4817-4832.
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David Lewis. 2001. Guide to Cytochromes P450. Guide to Cytochromes P450
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David F?V Lewis. (2001) COMPACT: a structural approach to the modelling of cytochromes P450 and their interactions with xenobiotics. Journal of Chemical Technology & Biotechnology 76:3, pages 237-244.
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David F.V. Lewis & Peter Hlavica. (2000) Interactions between redox partners in various cytochrome P450 systems: functional and structural aspects. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1460:2-3, pages 353-374.
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David F.V. Lewis. (2000) On the recognition of mammalian microsomal cytochrome P450 substrates and their characteristics. Biochemical Pharmacology 60:3, pages 293-306.
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Sharon Miksys, Ewa Hoffmann & Rachel F Tyndale. (2000) Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment. Biochemical Pharmacology 59:12, pages 1501-1511.
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Ronald E. White. (2000) High-Throughput Screening in Drug Metabolism and Pharmacokinetic Support of Drug Discovery. Annual Review of Pharmacology and Toxicology 40:1, pages 133-157.
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Johannes Schulze, Katharina Tschöp, Michael Lehnerer & Peter Hlavica. (2000) Residue 285 in Cytochrome P450 2B4 Lacking the NH2-Terminal Hydrophobic Sequence Has a Role in the Functional Association of NADPH–Cytochrome P450 Reductase. Biochemical and Biophysical Research Communications 270:3, pages 777-781.
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David F.V. Lewis, Brian G. Lake, Stephen G. George, Maurice Dickins, Peter J. Eddershaw, Michael H. Tarbit, Alan P. Beresford, Peter S. Goldfarb & F.Peter Guengerich. (1999) Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102. Toxicology 139:1-2, pages 53-79.
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David FV Lewis, Costas Ioannides & Dennis V Parke. (2016) A combined COMPACT and HazardExpert study of 40 chemicals for which information on mutagenicity and carcinogenicity is known, including the results of human epidemiological studies. Human & Experimental Toxicology 17:10, pages 577-586.
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D.F.V. Lewis, P.J. Eddershaw, M. Dickins, M.H. Tarbit & P.S. Goldfarb. (1998) Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate. Chemico-Biological Interactions 115:3, pages 175-199.
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D.F.V. Lewis, E. Watson & B.G. Lake. (1998) Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics. Mutation Research/Reviews in Mutation Research 410:3, pages 245-270.
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