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Xenobiotica
the fate of foreign compounds in biological systems
Volume 27, 1997 - Issue 2
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Research Article

Prediction of the pharmacokinetic parameters of reduced- dolasetron in man using in vitro-in vivo and interspecies allometric scaling

P. SANWALD-DUCRAY Marion Merrell Research Institute, Department of Drug Metabolism, 16 rue d’Ankara, 67080 Strasbou rg, France
&
J. DOW* Marion Merrell Research Institute, Department of Drug Metabolism, 16 rue d’Ankara, 67080 Strasbou rg, France
Pages 189-201 | Published online: 22 Sep 2008

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Pascal Espié, Dominique Tytgat, Maria-Laura Sargentini-Maier, Italo Poggesi & Jean-Baptiste Watelet. (2009) Physiologically based pharmacokinetics (PBPK). Drug Metabolism Reviews 41:3, pages 391-407.
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M. K. BAYLISS. (1999) Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man. Xenobiotica 29:3, pages 253-268.
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Articles from other publishers (12)

Xin Li, Zhigao Zhang, Yang Chen, Hong Wan, Jiakang Sun, Bin Wang, Bingqiang Feng, Bing Hu, Xingxing Shi, Jun Feng, Lei Zhang, Feng He, Chang Bai, Lianshan Zhang & Weikang Tao. (2019) Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood–Brain Barrier Penetration. ACS Medicinal Chemistry Letters 10:6, pages 996-1001.
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Christoph Thiel, Sebastian Schneckener, Markus Krauss, Ahmed Ghallab, Ute Hofmann, Tobias Kanacher, Sebastian Zellmer, Rolf Gebhardt, Jan G. Hengstler & Lars Kuepfer. (2015) A Systematic Evaluation of the Use of Physiologically Based Pharmacokinetic Modeling for Cross-Species Extrapolation. Journal of Pharmaceutical Sciences 104:1, pages 191-206.
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Urban Fagerholm. (2007) Prediction of human pharmacokinetics—evaluation of methods for prediction of hepatic metabolic clearance. Journal of Pharmacy and Pharmacology 59:6, pages 803-828.
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John C. Lipscomb & Torka S. Poet. (2008) In vitro measurements of metabolism for application in pharmacokinetic modeling. Pharmacology & Therapeutics 118:1, pages 82-103.
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Huadong Tang & Michael Mayersohn. (2006) A global examination of allometric scaling for predicting human drug clearance and the prediction of large vertical allometry**This work was presented at the American Association of Pharmaceutical Scientists Annual meeting, Salt Lake City, USA, Oct. 26, 2003.. Journal of Pharmaceutical Sciences 95:8, pages 1783-1799.
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Hannah M Jones, Neil Parrott, Karin Jorga & Thierry Lav??. (2006) A Novel Strategy for Physiologically Based Predictions of Human Pharmacokinetics. Clinical Pharmacokinetics 45:5, pages 511-542.
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Huadong Tang & Michael Mayersohn. (2005) A NOVEL MODEL FOR PREDICTION OF HUMAN DRUG CLEARANCE BY ALLOMETRIC SCALING. Drug Metabolism and Disposition 33:9, pages 1297-1303.
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Iftekhar Mahmood. (2005) The Correction Factors Do Help in Improving the Prediction of Human Clearance from Animal Data. Journal of Pharmaceutical Sciences 94:5, pages 940-945.
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K. Schneider, J. Oltmanns & M. Hassauer. (2004) Allometric principles for interspecies extrapolation in toxicological risk assessment—empirical investigations. Regulatory Toxicology and Pharmacology 39:3, pages 334-347.
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Hiroyoshi Hayakawa, Yoko Fukushima, Hiroshi Kato, Hiroyuki Fukumoto, Takumi Kadota, Hiroyuki Yamamoto, Hiroyuki Kuroiwa, Junko Nishigaki & Akira Tsuji. (2003) METABOLISM AND DISPOSITION OF NOVEL DES-FLUORO QUINOLONE GARENOXACIN IN EXPERIMENTAL ANIMALS AND AN INTERSPECIES SCALING OF PHARMACOKINETIC PARAMETERS. Drug Metabolism and Disposition 31:11, pages 1409-1418.
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Olivier Luttringer, Frank‐Peter Theil, Patrick Poulin, Anne H. Schmitt‐Hoffmann, Theodor Walter Guentert & Thierry Lavé. (2003) Physiologically Based Pharmacokinetic (PBPK) Modeling of Disposition of Epiroprim in Humans. Journal of Pharmaceutical Sciences 92:10, pages 1990-2007.
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Teh-Min Hu & William L. Hayton. (2015) Allometric scaling of xenobiotic clearance: Uncertainty versus universality. AAPS PharmSci 3:4, pages 30-43.
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