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Xenobiotica
the fate of foreign compounds in biological systems
Volume 27, 1997 - Issue 1
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Research Article

Selectivity of omeprazole inhibition towards rat liver cytochromes P450

K. Zomorodi Department of Pharmacy, University of Manchester, Manchester M13 9PL, UK
&
J. B. Houston Department of Pharmacy, University of Manchester, Manchester M13 9PL, UK
Pages 49-58 | Published online: 22 Sep 2008

Citations (11)

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Read on this site (1)

G. C. MOODY. (1999) Fully automated analysis of activities catalysed by the major human liver cytochrome P450 (CYP) enzymes: assessment of human CYP inhibition potential. Xenobiotica 29:1, pages 53-75.
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Articles from other publishers (10)

Amal M. ShoeibEman SaidElsayed M. Ammar. (2016) Cytoprotective potential of tiron and methyl palmitate against acetaminophen-induced acute liver injury. Canadian Journal of Physiology and Pharmacology 94:2, pages 147-154.
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E. Menteşe, F. Yılmaz, N. Karaali, S. Ülker & B. Kahveci. (2014) Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives. Russian Journal of Bioorganic Chemistry 40:3, pages 336-342.
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Annamaria Tonazzi, Ivano Eberini & Cesare Indiveri. (2013) Molecular Mechanism of Inhibition of the Mitochondrial Carnitine/Acylcarnitine Transporter by Omeprazole Revealed by Proteoliposome Assay, Mutagenesis and Bioinformatics. PLoS ONE 8:12, pages e82286.
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Bahittin Kahveci, Emre Menteşe, Musa Özil, Serdar Ülker & Murat Ertürk. (2013) An efficient synthesis of benzimidazoles via a microwave technique and evaluation of their biological activities. Monatshefte für Chemie - Chemical Monthly 144:7, pages 993-1001.
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Pedro Iñarrea, Alvaro Casanova, Maria Angeles Alava, María Iturralde & Enrique Cadenas. (2011) Melatonin and steroid hormones activate intermembrane Cu,Zn-superoxide dismutase by means of mitochondrial cytochrome P450. Free Radical Biology and Medicine 50:11, pages 1575-1581.
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Kristina Beijer, Alexandra Abrahamson, Björn Brunström & Ingvar Brandt. (2010) CYP1A inhibition in fish gill filaments: A novel assay applied on pharmaceuticals and other chemicals. Aquatic Toxicology 96:2, pages 145-150.
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Igor Semak, Elena Korik, Maria Antonova, Jacobo Wortsman & Andrzej Slominski. (2008) Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes. Journal of Pineal Research 45:4, pages 515-523.
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Joo H. Lee, Soo K. Bae, Jong W. Kwon, Won B. Kim & Myung G. Lee. (2005) Effects of omeprazole or cola beverage on the pharmacokinetics of oral DA‐8159, a new erectogenic, in rats. Biopharmaceutics & Drug Disposition 26:9, pages 411-416.
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J Velı́k, V Baliharová, J Fink-Gremmels, S Bull, J Lamka & L Skálová. (2004) Benzimidazole drugs and modulation of biotransformation enzymes. Research in Veterinary Science 76:2, pages 95-108.
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David F.V. Lewis & Brian G. Lake. (1998) Molecular modelling and quantitative structure-activity relationship studies on the interaction of omeprazole with cytochrome P450 isozymes. Toxicology 125:1, pages 31-44.
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