Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 27, 1997 - Issue 1
Submit an article Journal homepage
28
Views
17
CrossRef citations to date
0
Altmetric
Research Article

Covalent binding and inhibition of cytochrome P4502E1 by trichloroethylene

N. C. Halmes Division of Toxicology, University of Arkansas for Medical Sciences, Division of Toxicology, 4301 W. Markham St, Slot 638, Little Rock,AR 72205, USA
,
V. M. Samokyszyn Division of Toxicology, University of Arkansas for Medical Sciences, Division of Toxicology, 4301 W. Markham St, Slot 638, Little Rock,AR 72205, USA
&
N. R. Pumford Division of Toxicology, University of Arkansas for Medical Sciences, Division of Toxicology, 4301 W. Markham St, Slot 638, Little Rock,AR 72205, USA
Pages 101-110 | Published online: 22 Sep 2008

Citations (17)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Agneta Löf & Gunnar Johanson. (1998) Toxicokinetics of Organic Solvents: A Review of Modifying Factors. Critical Reviews in Toxicology 28:6, pages 571-650.
Read now

Articles from other publishers (16)

Na Zhu, Keqi Hu, Zihuan Li, Yuting Chen & Yungang Liu. (2019) Micronuclei Formation by Promutagens in Metabolism‐Incompetent V79 Cells Interacting With Activation‐Proficient Cells in Various Experimental Settings. Environmental and Molecular Mutagenesis 61:2, pages 224-234.
Crossref
Kathleen M. Gilbert. 2014. Trichloroethylene: Toxicity and Health Risks. Trichloroethylene: Toxicity and Health Risks 15 35 .
Wei Yuan, Hua Jin, Jou-Ku Chung & Jiang Zheng. (2010) Evidence for cellular protein covalent binding derived from styrene metabolite. Chemico-Biological Interactions 186:3, pages 323-330.
Crossref
Ornella I. Selmin, Patricia A. Thorne, Patricia T. Caldwell & Mallory R. Taylor. (2008) Trichloroethylene and Trichloroacetic Acid Regulate Calcium Signaling Pathways in Murine Embryonal Carcinoma Cells P19. Cardiovascular Toxicology 8:2, pages 47-56.
Crossref
Ping Cai, Rolf König, Paul J. Boor, Shakuntala Kondraganti, Bhupendra S. Kaphalia, M. Firoze Khan & G.A.S. Ansari. (2008) Chronic exposure to trichloroethene causes early onset of SLE-like disease in female MRL +/+ mice. Toxicology and Applied Pharmacology 228:1, pages 68-75.
Crossref
Ping Cai, Rolf König, M. Firoze Khan, Suimin Qiu, Bhupendra S. Kaphalia & G.A.S. Ansari. (2006) Autoimmune response in MRL+/+ mice following treatment with dichloroacetyl chloride or dichloroacetic anhydride. Toxicology and Applied Pharmacology 216:2, pages 248-255.
Crossref
Shelley Brown DuTeaux, Matt J. Hengel, Danica E. DeGroot, Karen A. Jelks & Marion G. Miller. (2003) Evidence for Trichloroethylene Bioactivation and Adduct Formation in the Rat Epididymis and Efferent Ducts1. Biology of Reproduction 69:3, pages 771-779.
Crossref
Danièle Lucas. 2003. Reviews in Food and Nutrition Toxicity. Reviews in Food and Nutrition Toxicity 284 304 .
Hiroyoshi Fujita, Chiaki Nishitani & Kazuhiro Ogawa. (2002) Regulatory heme and trichloroethylene intoxication: A possible explanation of the case of “A Civil Action”. Environmental Health and Preventive Medicine 7:3, pages 103-112.
Crossref
Mary-Laure Vidal, Anne Bassères & Jean-François Narbonne. (2001) Potential biomarkers of trichloroethylene and toluene exposure in Corbicula fluminea. Environmental Toxicology and Pharmacology 9:3, pages 87-97.
Crossref
James L Merdink, Richard J Bull & Irvin R Schultz. (2000) Trapping and identification of the dichloroacetate radical from the reductive dehalogenation of trichloroacetate by mouse and rat liver microsomes. Free Radical Biology and Medicine 29:2, pages 125-130.
Crossref
K.M. Lee, S. Muralidhara, C.A. White & J.V. Bruckner. (2000) Mechanisms of the Dose-Dependent Kinetics of Trichloroethylene: Oral Bolus Dosing of Rats. Toxicology and Applied Pharmacology 164:1, pages 55-64.
Crossref
K.M. Lee, S. Muralidhara, R.G. Schnellmann & J.V. Bruckner. (2000) Contribution of Direct Solvent Injury to the Dose-Dependent Kinetics of Trichloroethylene: Portal Vein Administration to Rats. Toxicology and Applied Pharmacology 164:1, pages 46-54.
Crossref
Joseph M Griffin, Sarah J Blossom, Stephanie K Jackson, Kathleen M Gilbert & Neil R Pumford. (2000) Trichloroethylene accelerates an autoimmune response by Th1 T cell activation in MRL+/+ mice. Immunopharmacology 46:2, pages 123-137.
Crossref
Joseph M Griffin, John C Lipscomb & Neil R Pumford. (1998) Covalent binding of trichloroethylene to proteins in human and rat hepatocytes. Toxicology Letters 95:3, pages 173-181.
Crossref
N.Christine Halmes, Everett J. Perkins, David C. McMillan & Neil R. Pumford. (1997) Detection of trichloroethylene-protein adducts in rat liver and plasma. Toxicology Letters 92:3, pages 187-194.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.