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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 10
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Research Article

Biotransformation of 2-chloroaniline in the Fischer 344 rat: identification of urinary metabolites

S. K. HONG Department of Pharmacology, Marshall University School of Medicine, 1542 Spring Valley Drive Huntington, WV 25704-9388, USA
Pages 985-994 | Published online: 22 Sep 2008

Citations (10)

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Toby J. Athersuch, Ian D. Wilson, Hector C. Keun & John C. Lindon. (2013) Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry. Xenobiotica 43:9, pages 792-802.
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G. B. Scarfe, I. D. Wilson, M. A. Warne, E. Holmes, J. K. Nicholson & J. C. Lindon. (2002) Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry. Xenobiotica 32:4, pages 267-277.
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Articles from other publishers (8)

Megumi SUDA, Yukie YANAGIBA, Tatsushi TOYOOKA, Rui-Sheng WANG & Shigeki KODA. (2021) The Quantitative Analysis Method of Urinary Aromatic Amines and Their Metabolites using Liquid Chromatography -Tandem Mass Spectrometry with Correction for Matrix Effectsマトリックス効果を補正する液体クロマトグラフィ̶タンデム型質量分析装置を用いたヒト尿中芳香族アミン類の定量方法. Journal of Occupational Safety and Health 14:1, pages 3-14.
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Gary O. Rankin, Christopher R. Racine, Monica A. Valentovic & Dianne K. Anestis. (2020) Nephrotoxic Potential of Putative 3,5-Dichloroaniline (3,5-DCA) Metabolites and Biotransformation of 3,5-DCA in Isolated Kidney Cells from Fischer 344 Rats. International Journal of Molecular Sciences 22:1, pages 292.
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Gabriele Sabbioni. (2017) Hemoglobin Adducts and Urinary Metabolites of Arylamines and Nitroarenes. Chemical Research in Toxicology 30:10, pages 1733-1766.
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Christopher R. Racine, Travis Ferguson, Debbie Preston, Dakota Ward, John Ball, Dianne Anestis, Monica Valentovic & Gary O. Rankin. (2016) The role of biotransformation and oxidative stress in 3,5-dichloroaniline (3,5-DCA) induced nephrotoxicity in isolated renal cortical cells from male Fischer 344 rats. Toxicology 341-343, pages 47-55.
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Christopher Racine, Dakota Ward, Dianne Anestis, Travis Ferguson, Deborah Preston & Gary Rankin. (2014) 3,4,5-Trichloroaniline Nephrotoxicity in Vitro: Potential Role of Free Radicals and Renal Biotransformation. International Journal of Molecular Sciences 15:11, pages 20900-20912.
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Gary O. Rankin, Adam Sweeney, Christopher Racine, Travis Ferguson, Deborah Preston & Dianne K. Anestis. (2014) 4-Amino-2-chlorophenol: Comparative in vitro nephrotoxicity and mechanisms of bioactivation. Chemico-Biological Interactions 222, pages 126-132.
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Gary O. Rankin, Suk-kil Hong, Dianne K. Anestis, John G. Ball & Monica A. Valentovic. (2008) Mechanistic aspects of 4-amino-2,6-dichlorophenol-induced in vitro nephrotoxicity. Toxicology 245:1-2, pages 123-129.
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Richard M Niles, Carla P Cook, Gary G Meadows, Ya-Min Fu, Jerry L McLaughlin & Gary O Rankin. (2006) Resveratrol Is Rapidly Metabolized in Athymic (Nu/Nu) Mice and Does Not Inhibit Human Melanoma Xenograft Tumor Growth. The Journal of Nutrition 136:10, pages 2542-2546.
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