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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 9
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Research Article

Induction of pulmonary CYP1A1 by nicotine

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Pages 827-843 | Published online: 22 Sep 2008

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Blaine Phillips, Marco Esposito, Jan Verbeeck, Stéphanie Boué, Anita Iskandar, Gregory Vuillaume, Patrice Leroy, Subash Krishnan, Ulrike Kogel, Aneli Utan, Walter K. Schlage, Monali Bera, Emilija Veljkovic, Julia Hoeng, Manuel C. Peitsch & Patrick Vanscheeuwijck. (2015) Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague–Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology. Inhalation Toxicology 27:9, pages 405-431.
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Kareemah Gamieldien & Gert S. Maritz. (2004) POSTNATAL EXPRESSION OF CYTOCHROME P450 1A1, 2A3, AND 2B1 mRNA IN NEONATAL RAT LUNG: INFLUENCE OF MATERNAL NICOTINE EXPOSURE. Experimental Lung Research 30:2, pages 121-133.
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Janne Hukkanen, Peyton Jacob III, Margaret Peng, Delia Dempsey & Neal L. Benowitz. (2011) Effect of nicotine on cytochrome P450 1A2 activity. British Journal of Clinical Pharmacology 72:5, pages 836-838.
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Michael S. DenisonScott R. Nagy. (2003) Activation of the Aryl Hydrocarbon Receptor by Structurally Diverse Exogenous and Endogenous Chemicals. Annual Review of Pharmacology and Toxicology 43:1, pages 309-334.
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Cindy Wei, Robert J Caccavale, Eric H Weyand, Suzie Chen & Michael M Iba. (2002) Induction of CYP1A1 and CYP1A2 expressions by prototypic and atypical inducers in the human lung. Cancer Letters 178:1, pages 25-36.
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Michael M. Iba & Jacqueline Fung. (2001) Pulmonary CYP1A1 and CYP1A2 levels and activities in adult male and female offspring of rats exposed during gestation and lactation to 2,3,7,8-tetrachlorodibenzo-p-dioxin11Abbreviations: AhR, aryl hydrocarbon receptor; ARNT, AhR nuclear translocator; AUC, area under the curve; B[a]P, benzo[a]pyrene; CYP1A, used to include CYP1A1 and CYP1A2; EROD, ethoxyresorufin O-deethylase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; MeIQ, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline; PCR, polymerase chain reaction; PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; and TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin.. Biochemical Pharmacology 62:5, pages 617-626.
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Yu-Dan Wei, Linda Bergander, Ulf Rannug & Agneta Rannug. (2000) Regulation of CYP1A1 Transcription via the Metabolism of the Tryptophan-Derived 6-Formylindolo[3,2-b]carbazole. Archives of Biochemistry and Biophysics 383:1, pages 99-107.
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Margie L. Clapper. (2000) Genetic polymorphism and cancer risk. Current Oncology Reports 2:3, pages 251-256.
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Michael M. Iba, Jacqueline Fung, John V. Giannone & Allan B. Okey. (2000) Comparative Induction of CYP1A1 Expression by Pyridine and Its Metabolites. Archives of Biochemistry and Biophysics 378:2, pages 299-310.
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Michael M Iba & Jacqueline Fung. (1999) Induction of pulmonary cytochrome P4501A1: interactive effects of nicotine and mecamylamine. European Journal of Pharmacology 383:3, pages 399-403.
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Michael M Iba, Jawed Alam, Cheri Touchard, Paul E Thomas, Anima Ghosal & Jacqueline Fung. (1999) Coordinate up-regulation of CYP1A1 and heme oxygenase-1 (HO-1) expression and modulation of δ-aminolevulinic acid synthase and tryptophan pyrrolase activities in pyridine-treated rats. Biochemical Pharmacology 58:4, pages 723-734.
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