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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 7
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Research Article

Metabolism of 2-ethylhexanoic acid administered orally or dermally to the female Fischer 344 rat1

J. C. ENGLISH Health and Environment Laboratories, Eastman Kodak Company, Kodak Park, Building 320, Rochester, NY, 14652-6272, USA
,
P. J. DEISINGER Health and Environment Laboratories, Eastman Kodak Company, Kodak Park, Building 320, Rochester, NY, 14652-6272, USA
&
D. GUEST Health and Environment Laboratories, Eastman Kodak Company, Kodak Park, Building 320, Rochester, NY, 14652-6272, USA
Pages 699-714 | Published online: 22 Sep 2008

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Timothy R. Fennell, James M. Mathews, Rodney W. Snyder, Yan Hong, Scott L. Watson, Sherry R. Black, Barry S. McIntyre & Suramya Waidyanatha. (2018) Metabolism and disposition of 2-ethylhexyl-p-methoxycinnamate following oral gavage and dermal exposure in Harlan Sprague Dawley rats and B6C3F1/N mice and in hepatocytes in vitro. Xenobiotica 48:11, pages 1142-1156.
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Articles from other publishers (9)

David Hala, Lene H. Petersen, Duane B. Huggett, Michelle A. Puchowicz, Henri Brunengraber & Guo-Fang Zhang. (2021) Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats. International Journal of Molecular Sciences 22:24, pages 13489.
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Joseph P. Dewulf, Stéphanie Paquay, Etienne Marbaix, Younès Achouri, Emile Van Schaftingen & Guido T. Bommer. (2021) ECHDC1 knockout mice accumulate ethyl-branched lipids and excrete abnormal intermediates of branched-chain fatty acid metabolism. Journal of Biological Chemistry 297:4, pages 101083.
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Lisa E. Kratz & Jessica S. Albert. (2016) 2-Ethylhexanoic acid, found in common plasticizers, leads to an artificial increase in C8 acylcarnitine levels in two neonates treated with extracorporeal membrane oxygenation (ECMO). Clinica Chimica Acta 461, pages 59-60.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 95 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 12 .
. (2009) Flavouring Group Evaluation 04 −2-Ethylhexyl derivatives from chemical group 2 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC). EFSA Journal 7:1, pages 929.
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Dana Stingel, Peter Feldmeier, Elke Richling, Michael Kempf, Sandra Elss, Samira Labib & Peter Schreier. (2007) Urinary 2‐ethyl‐3‐oxohexanoic acid as major metabolite of orally administered 2‐ethylhexanoic acid in human. Molecular Nutrition & Food Research 51:3, pages 301-306.
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. (2016) Annual Review of Cosmetic Ingredient Safety Assessments—2002/20031. International Journal of Toxicology 24:1_suppl, pages 1-102.
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Valerie Walker & Graham A Mills. (2001) Urine 4-heptanone: a β-oxidation product of 2-ethylhexanoic acid from plasticisers. Clinica Chimica Acta 306:1-2, pages 51-61.
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