Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 6
Submit an article Journal homepage
83
Views
21
CrossRef citations to date
0
Altmetric
Research Article

Comparative metabolism of ortho-phenylphenol in mouse, rat and man

M. J. BARTELS Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
,
D. A. McNETT Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
,
C. TIMCHALK Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
,
A. L. MENDRALA Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
,
W. R. CHRISTENSON Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
,
G. K. SANGHA Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
,
K. A. BRZAK Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
&
S. N. SHABRANG Health and Environmental Research Laboratory, The Dow Chemical Co., 1803 Building, Midland, MI 48674, USA OE Battelle Paci c Northwest Laboratories, Richland, WA, USA Toxicology Laboratory, Agriculture Division, The Bayer Corp., Stilwell, KS, 66085, USA
 show all
Pages 579-594 | Published online: 22 Sep 2008

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

E.M. Bomhard, S.Y. Brendler-Schwaab, A. Freyberger, B.A. Herbold, K.H. Leser & M. Richter. (2002) O-Phenylphenol and its Sodium and Potassium Salts: A Toxicological Assessment. Critical Reviews in Toxicology 32:6, pages 551-626.
Read now

Articles from other publishers (20)

Finis L. Cavender & John L. O'Donoghue. 2003. Patty's Toxicology. Patty's Toxicology 1 106 .
Jean-Yves Sancéau, Patrick Bélanger, René Maltais & Donald Poirier. (2022) An Improved Synthesis of Glucuronide Metabolites of Hindered Phenolic Xenoestrogens. Current Organic Synthesis 19:7, pages 838-845.
Crossref
Choon Fu Goh, Long Chiau Ming & Li Ching Wong. (2021) Dermatologic reactions to disinfectant use during the COVID-19 pandemic. Clinics in Dermatology 39:2, pages 314-322.
Crossref
René Bérubé, Patrick Bélanger, Jean-François Bienvenu, Pierre Dumas, Gilles Provencher, Éric Gaudreau & Normand Fleury. (2018) New approach for the determination of ortho-phenylphenol exposure by measurement of sulfate and glucuronide conjugates in urine using liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry 410:28, pages 7275-7284.
Crossref
Shiliang A. Liu, Brent A. Stanfield, Vladimir N. Chouljenko, Shan Naidu, Ingeborg Langohr, Fabio Del Piero, Jacqueline Ferracone, Alma A. Roy & Konstantin G. Kousoulas. (2017) Intramuscular Immunization of Mice with the Live-Attenuated Herpes Simplex Virus 1 Vaccine Strain VC2 Expressing Equine Herpesvirus 1 (EHV-1) Glycoprotein D Generates Anti-EHV-1 Immune Responses in Mice. Journal of Virology 91:12.
Crossref
Emma Nixon, James D. Brooks, Patricia A. Routh, Jason T. Chittenden & Ronald E. Baynes. (2016) Pharmacokinetics of 14 C‐ortho‐phenylphenol following intravenous administration in pigs . Journal of Applied Toxicology 37:4, pages 508-512.
Crossref
Caroline L. Pinto, Kamel Mansouri, Richard Judson & Patience Browne. (2016) Prediction of Estrogenic Bioactivity of Environmental Chemical Metabolites. Chemical Research in Toxicology 29:9, pages 1410-1427.
Crossref
A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1067 1110 .
Finis L. Cavender & John O'Donohue. 2003. Patty's Toxicology. Patty's Toxicology 1 108 .
Leslie London, David Coggon, Angelo Moretto, Peter Westerholm, Martin F Wilks & Claudio Colosio. (2010) The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas. Environmental Health 9:1.
Crossref
Ceri Lewis, Siham Beggah, Chris Pook, Carlos Guitart, Clare Redshaw, Jan Roelof van der Meer, James W. Readman & Tamara Galloway. (2008) Novel Use of a Whole Cell E. coli Bioreporter as a Urinary Exposure Biomarker . Environmental Science & Technology 43:2, pages 423-428.
Crossref
Mehmet Coelhan, Jim T. Yu & A. Lynn Roberts. (2009) Presence of the biocide ortho-phenylphenol in canned soft drinks in the United States and Germany. Food Chemistry 112:2, pages 515-519.
Crossref
Monique W.J den Brok, Sabien C.van der Schoot, Bastiaan Nuijen, Michel J.X Hillebrand & Jos H Beijnen. (2004) 2-hydroxypropyl-β-cyclodextrin extracts 2-phenylphenol from silicone tubing. International Journal of Pharmaceutics 278:2, pages 303-309.
Crossref
N Niho, M Shibutani, K Toyoda, H Sato, A Hirose, K Imaida, M Takahashi, Y Hayashi & M Hirose. (2002) Dose– and time–response studies of sodium o-phenylphenate urinary bladder carcinogenicity in rats. Food and Chemical Toxicology 40:5, pages 715-722.
Crossref
Nicole H.P. Cnubben, Graham R. Elliott, Betty C. Hakkert, Wim J.A. Meuling & Johannes J.M. van de Sandt. (2002) Comparative in Vitro–in Vivo Percutaneous Penetration of the Fungicide ortho-Phenylphenol. Regulatory Toxicology and Pharmacology 35:2, pages 198-208.
Crossref
Ralph Gingell, John O'Donoghue, Robert J. Staab, Ira W. Daly, Bruce K. Bernard, Anish Ranpuria, E. John Wilkinson, Daniel Woltering, Phillip A. Johns, Stephen B. Montgomery, Larry E. Hammond & Marguerita L. Leng. 2003. Patty's Toxicology. Patty's Toxicology.
E. J. Oliveira & D. G. Watson. (2000) Liquid chromatography-mass spectrometry in the study of the metabolism of drugs and other xenobiotics. Biomedical Chromatography 14:6, pages 351-372.
Crossref
K Walton, R Walker, J.J.M van de Sandt, J.V Castell, A.G.A.A Knapp, G Kozianowski, M Roberfroid & B Schilter. (1999) The application of in vitro data in the derivation of the Acceptable Daily Intake of food additives. Food and Chemical Toxicology 37:12, pages 1175-1197.
Crossref
C Timchalk, S Selim, G Sangha & M J Bartels. (2016) The pharmacokinetics and metabolism of 14C/13C-labeled ortho-phenylphenol formation following dermal application to human volunteers. Human & Experimental Toxicology 17:8, pages 411-417.
Crossref
Raymond A. Smith, W.Russ Christenson, Michael J. Bartels, Lora L. Arnold, Margaret K. St. John, Martin Cano, Emily M. Garland, Stephen G. Lake, Bradley S. Wahle, Debra A. McNett & Samuel M. Cohen. (1998) Urinary Physiologic and Chemical Metabolic Effects on the Urothelial Cytotoxicity and Potential DNA Adducts ofo-Phenylphenol in Male Rats. Toxicology and Applied Pharmacology 150:2, pages 402-413.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.