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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 5
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Research Article

Glutathione S-transferases in human renal cortex and neoplastic tissue : enzymatic activity, isoenzyme profile and immunohistochemical localization

V. RODILLA* Departments of Medicine and Therapeutics and Biomedical Sciences, Department of Pathology, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK OE Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA
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A. A. BENZIE Departments of Medicine and Therapeutics and Biomedical Sciences, Department of Pathology, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK OE Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA
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J. M. VEITCH Departments of Medicine and Therapeutics and Biomedical Sciences, Department of Pathology, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK OE Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA
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G. I. MURRAY Departments of Medicine and Therapeutics and Biomedical Sciences, Department of Pathology, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK OE Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA
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J. D. ROWE Departments of Medicine and Therapeutics and Biomedical Sciences, Department of Pathology, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK OE Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA
&
G. M. HAWKSWORTH Departments of Medicine and Therapeutics and Biomedical Sciences, Department of Pathology, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK OE Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Pages 443-456 | Published online: 22 Sep 2008

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H. M. Korashy, R. H. Elbekai & A. O. S. El-Kadi. (2004) Effects of renal diseases on the regulation and expression of renal and hepatic drug-metabolizing enzymes: a review. Xenobiotica 34:1, pages 1-29.
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Articles from other publishers (14)

Xingyu Peng, Jinfeng Zhu, Sicheng Liu, Zitao Liu, Chen Luo, Xun Wu, Zhonglin Yu & Zhengming Zhu. (2023) The Upregulation of GSTO2 is Associated with Colon Cancer Progression and a Poor Prognosis. Journal of Oncology 2023, pages 1-21.
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Marija Pljesa-Ercegovac, Ana Savic-Radojevic, Marija Matic, Vesna Coric, Tatjana Djukic, Tanja Radic & Tatjana Simic. (2018) Glutathione Transferases: Potential Targets to Overcome Chemoresistance in Solid Tumors. International Journal of Molecular Sciences 19:12, pages 3785.
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L.H. Lash & B.S. Cummmings. 2018. Comprehensive Toxicology. Comprehensive Toxicology 56 97 .
Lawrence H. Lash, Weihsueh A. Chiu, Kathryn Z. Guyton & Ivan Rusyn. (2014) Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity. Mutation Research/Reviews in Mutation Research 762, pages 22-36.
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Shiekh Tanveer AhmadWani ArjumandAmlesh SethAshish Kumar SainiSarwat Sultana. (2012) Impact of Glutathione Transferase M1, T1, and P1 Gene Polymorphisms in the Genetic Susceptibility of North Indian Population to Renal Cell Carcinoma . DNA and Cell Biology 31:4, pages 636-643.
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Anne-Laure Bauchet, Regis Masson, Magali Guffroy & Mohamed Slaoui. (2011) Immunohistochemical Identification of Kidney Nephron Segments in the Dog, Rat, Mouse, and Cynomolgus Monkey. Toxicologic Pathology 39:7, pages 1115-1128.
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Michela De Martino, Tobias Klatte, Georg Schatzl, Mesut Remzi, Matthias Waldert, Andrea Haitel, Igor Stancik, Gero Kramer & Michael Marberger. (2010) Renal Cell Carcinoma Fuhrman Grade and Histological Subtype Correlate With Complete Polymorphic Deletion of Glutathione S-Transferase M1 Gene. Journal of Urology 183:3, pages 878-883.
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L.H. Lash & B.S. Cummings. 2010. Comprehensive Toxicology. Comprehensive Toxicology 81 115 .
Tatjana Simic, Ana Savic-Radojevic, Marija Pljesa-Ercegovac, Marija Matic & Jasmina Mimic-Oka. (2009) Glutathione S-transferases in kidney and urinary bladder tumors. Nature Reviews Urology 6:5, pages 281-289.
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Marija Pljesa-Ercegovac, Jasmina Mimic-Oka, Dejan Dragicevic, Ana Savic-Radojevic, Marija Opacic, Steva Pljesa, Radoslav Radosavljevic & Tatjana Simic. (2008) Altered antioxidant capacity in human renal cell carcinoma: Role of glutathione associated enzymes. Urologic Oncology: Seminars and Original Investigations 26:2, pages 175-181.
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T. Simic, M. Pljesa-Ercegovac, A. Savic-Radojevic, M. Hadziahmetovic & J. Mimic-Oka. (2006) Identification of a glutathione S-transferase without affinity for glutathione sepharose in human kidney. Amino Acids 30:4, pages 495-498.
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Ricarda Thier, Thomas Brüning, Peter H. Roos, Hans-Peter Rihs, Klaus Golka, Yon Ko & Hermann M. Bolt. (2003) Markers of genetic susceptibility in human environmental hygiene and toxicology: The role of selected CYP, NAT and GST genes. International Journal of Hygiene and Environmental Health 206:3, pages 149-171.
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M.T.M. Raijmakers, E.A.P. Steegers & W.H.M. Peters. (2001) Glutathione S-transferases and thiol concentrations in embryonic and early fetal tissues. Human Reproduction 16:11, pages 2445-2450.
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Brian S Cummings, Jean C Parker & Lawrence H Lash. (2000) Role of cytochrome P450 and glutathione S-transferase α in the metabolism and cytotoxicity of trichloroethylene in rat kidney. Biochemical Pharmacology 59:5, pages 531-543.
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