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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 5
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Research Article

Enzyme-inducing effects of bicalutamide in mouse, rat and dog

D. McKILLOP* Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Maccleseld SK10 4TG, UK
,
C. J. BUTTERS Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Maccleseld SK10 4TG, UK
,
S. J. HILL Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Maccleseld SK10 4TG, UK
,
P. J. SIMONS Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Maccleseld SK10 4TG, UK
,
T. L. EDWARDS Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Maccleseld SK10 4TG, UK
&
S. E. DOUGHTY Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Maccleseld SK10 4TG, UK
Pages 465-478 | Published online: 22 Sep 2008

Citations (9)

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Read on this site (2)

Paul Schellhammer. (1999) An update on bicalutamide in the treatment of prostate cancer. Expert Opinion on Investigational Drugs 8:6, pages 849-860.
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M. STROLIN BENEDETTI & M. BANI. (1999) METABOLISM-BASED DRUG INTERACTIONS INVOLVING ORAL AZOLE ANTIFUNGALS IN HUMANS*. Drug Metabolism Reviews 31:3, pages 665-717.
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Articles from other publishers (7)

Antonio Guzmán, Araceli Tortajada, Ana-Paz Marín, Cristina Vila & Gregorio Encina. (2022) Results from two-year rodent oral carcinogenicity studies of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator. Regulatory Toxicology and Pharmacology 132, pages 105182.
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Peter J.M. Clements, Brad Bolon, Elizabeth McInnes, Sydney Mukaratirwa & Cheryl Scudamore. 2022. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology 653 694 .
John R. Foster. (2016) Spontaneous and Drug-Induced Hepatic Pathology of the Laboratory Beagle Dog, the Cynomolgus Macaque and the Marmoset. Toxicologic Pathology 33:1, pages 63-74.
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Ian D Cockshott. (2004) Bicalutamide. Clinical Pharmacokinetics 43:13, pages 855-878.
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R Tandler, M Kondruweit, T Fischlein & M Weyand. (2003) Hormone therapy in men—increased risk of cardiac allograft rejection?. The Journal of Heart and Lung Transplantation 22:7, pages 831.
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Richard A. Graham, April Downey, Dan Mudra, Linda Krueger, Kathy Carroll, Christopher Chengelis, Ajay Madan & Andrew Parkinson. (2002) In Vivo and in Vitro Induction of Cytochrome P450 Enzymes in Beagle Dogs. Drug Metabolism and Disposition 30:11, pages 1206-1213.
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D.E Amacher, S.J Schomaker & J.E Burkhardt. (2001) The relationship among microsomal enzyme induction, liver weight and histological change in beagle dog toxicology studies. Food and Chemical Toxicology 39:8, pages 817-825.
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