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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 2
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Research Article

Metabolism of a novel CCK-B antagonist in rat, dog and human liver microsomes

M. KAJBAF Glaxo Wellcome S.p.A., Medicines Research Centre, via Fleming, 4, 37100 Verona, Italy
,
P. ROSSATO Glaxo Wellcome S.p.A., Medicines Research Centre, via Fleming, 4, 37100 Verona, Italy
,
J. R. BARNABY Glaxo Wellcome S.p.A., Medicines Research Centre, via Fleming, 4, 37100 Verona, Italy
&
M. PELLEGATTI Glaxo Wellcome S.p.A., Medicines Research Centre, via Fleming, 4, 37100 Verona, Italy
Pages 167-178 | Published online: 22 Sep 2008

Citations (7)

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M. KAJBAF, C. MARCHIORO, J. R. BARNABY & M. PELLEGATTI. (1998) In vivo metabolism of a novel cholecystokinin B (CCK-B) antagonist in rat and dog plasma and rat faeces. Xenobiotica 28:8, pages 785-794.
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Articles from other publishers (6)

Jakob Wallgren, Svante Vikingsson, Anna Åstrand, Martin Josefsson, Henrik Gréen, Johan Dahlén, Xiongyu Wu & Peter Konradsson. (2018) Synthesis and identifications of potential metabolites as biomarkers of the synthetic cannabinoid AKB-48. Tetrahedron 74:24, pages 2905-2913.
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Jakob Wallgren, Svante Vikingsson, Anders Johansson, Martin Josefsson, Henrik Green, Johan Dahlén, Xiongyu Wu & Peter Konradsson. (2017) Synthesis and identification of an important metabolite of AKB-48 with a secondary hydroxyl group on the adamantyl ring. Tetrahedron Letters 58:15, pages 1456-1458.
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Lukas Wanka, Khalid Iqbal & Peter R. Schreiner. (2013) The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives. Chemical Reviews 113:5, pages 3516-3604.
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Sampath-Kumar Anandan, Heather Kay Webb, Dawn Chen, Yi-Xin (Jim) Wang, Basker R. Aavula, Sylvaine Cases, Ying Cheng, Zung N. Do, Upasana Mehra, Vinh Tran, Jon Vincelette, Joanna Waszczuk, Kathy White, Kenneth R. Wong, Le-Ning Zhang, Paul D. Jones, Bruce D. Hammock, Dinesh V. Patel, Randall Whitcomb, D. Euan MacIntyre, James Sabry & Richard Gless. (2011) 1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia. Bioorganic & Medicinal Chemistry Letters 21:3, pages 983-988.
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Sampath-Kumar Anandan, Heather K. Webb, Zung N. Do & Richard D. Gless. (2009) Unsymmetrical non-adamantyl N,N′-diaryl urea and amide inhibitors of soluble expoxide hydrolase. Bioorganic & Medicinal Chemistry Letters 19:15, pages 4259-4263.
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M. Kajbaf, P. Rossato, L. Ferrari, P. Grossi & M. Pellegatti. (1997) In vitro metabolism of GV150013X by using liver microsomes and liver tissue slices from different species. European Journal of Drug Metabolism and Pharmacokinetics 22:4, pages 359-366.
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