Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 29, 1999 - Issue 12
Submit an article Journal homepage
100
Views
25
CrossRef citations to date
0
Altmetric
Research Article

Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds

M. Nakajima Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 9200934, Japan
,
M. Suzuki Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 9200934, Japan
,
R. Yamaji Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 9200934, Japan
,
H. Takashina Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 9200934, Japan
,
N. Shimada Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 9200934, Japan
,
H. Yamazaki Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 9200934, Japan
&
T. Yokoi Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 9200934, Japan
 show all
Pages 1191-1202 | Published online: 22 Sep 2008

Citations (25)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Vladimir Zlabek, AnnaLotta Schiller Vestergren, Sofia Trattner, Liane Wagner, Jana Pickova & Galia Zamaratskaia. (2015) Stimulatory effect of sesamin on hepatic cytochrome P450 activities in Atlantic salmon (Salmo salar L.) is not directly associated with expression of genes related to xenobiotic metabolism. Xenobiotica 45:7, pages 598-604.
Read now
Michael Murray. (2012) Toxicological Actions of Plant-Derived and Anthropogenic Methylenedioxyphenyl-Substituted Chemicals in Mammals and Insects. Journal of Toxicology and Environmental Health, Part B 15:6, pages 365-395.
Read now
Kaori Yasuda & Toshiyuki Sakaki. (2012) How is sesamin metabolised in the human liver to show its biological effects?. Expert Opinion on Drug Metabolism & Toxicology 8:1, pages 93-102.
Read now
Jeffrey A Kramer. (2008) Designing safe drugs: what to consider?. Expert Opinion on Drug Discovery 3:7, pages 707-713.
Read now
Y. Hara, M. Nakajima, K.-I. Miyamoto & T. Yokoi. (2005) Inhibitory effects of psychotropic drugs on mexiletine metabolism in human liver microsomes: Prediction of in vivo drug interactions. Xenobiotica 35:6, pages 549-560.
Read now
Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
Read now

Articles from other publishers (19)

Ziru Dai, Yue Wu, Yuan Xiong, Jingjing Wu, Min Wang, Xiao Sun, Xinxin Ding, Ling Yang, Xiaobo Sun & Guangbo Ge. (2023) CYP1A inhibitors: Recent progress, current challenges, and future perspectives. Medicinal Research Reviews 44:1, pages 169-234.
Crossref
M. Saeed Mirzaei, Maxim V. Ivanov, Avat Arman Taherpour & Saber Mirzaei. (2021) Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights. Chemical Research in Toxicology 34:4, pages 959-987.
Crossref
Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio & Maija Lahtela-Kakkonen. (2015) Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis. Drug Metabolism and Disposition 43:12, pages 1891-1904.
Crossref
Kaori Yasuda, Sera Ueno, Erika Ueda, Miyu Nishikawa, Kie Takeda, Masaki Kamakura, Shinichi Ikushiro & Toshiyuki Sakaki. (2015) Influence of sesamin on CYP 2C‐mediated diclofenac metabolism: in vitro and in vivo analysis . Pharmacology Research & Perspectives 3:5.
Crossref
Rawan Albadareen, Stephen ThorntonArezou Heshmati, Roy Gerona & Jennifer Lowry. (2015) Unusually Prolonged Presentation of Designer Drug Encephalopathy Responsive to Steroids. Pediatrics 136:1, pages e246-e248.
Crossref
Maria Almira Correia & Paul. F. Hollenberg. 2015. Cytochrome P450. Cytochrome P450 177 259 .
Satoshi Yamaori, Yoshimi Okushima, Ikuo Yamamoto & Kazuhito Watanabe. (2014) Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol. Chemico-Biological Interactions 215, pages 62-68.
Crossref
Alexander V. LyubimovBill Gurley, Kim E. Fifer & Zöe Gardner. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 79 .
Alexander V. LyubimovDeepak K. Dalvie. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 54 .
Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta & Toshiyuki Sakaki. (2011) Sequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human Liver. Drug Metabolism and Disposition 39:9, pages 1538-1545.
Crossref
Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Miho Ohta & Toshiyuki Sakaki. (2010) Metabolism of Sesamin by Cytochrome P450 in Human Liver Microsomes. Drug Metabolism and Disposition 38:12, pages 2117-2123.
Crossref
Cengiz Gokbulut. (2010) Sesame Oil: Potential Interaction with P450 Isozymes. Journal of Pharmacology and Toxicology 5:8, pages 469-472.
Crossref
Bernard P. Murray. 2009. Annual Reports in Medicinal Chemistry Volume 44. Annual Reports in Medicinal Chemistry Volume 44 535 553 .
Sonia M. Poli. 2008. Antitargets. Antitargets 267 276 .
B J Gurley, A Swain, M A Hubbard, F Hartsfield, J Thaden, D K Williams, W B Gentry & Y Tong. (2007) Supplementation With Goldenseal (Hydrastis canadensis), but not Kava Kava (Piper methysticum), Inhibits Human CYP3A Activity In Vivo. Clinical Pharmacology & Therapeutics 83:1, pages 61-69.
Crossref
Bill J. Gurley, Ashley Swain, Gary W. Barone, D. Keith Williams, Philip Breen, C. Ryan Yates, Leslie B. Stuart, Martha A. Hubbard, Yudong Tong & Sreekhar Cheboyina. (2007) Effect of Goldenseal ( Hydrastis canadensis ) and Kava Kava ( Piper methysticum ) Supplementation on Digoxin Pharmacokinetics in Humans . Drug Metabolism and Disposition 35:2, pages 240-245.
Crossref
Miki Katoh, Toshiro Sawada, Yoshinori Soeno, Miki Nakajima, Chise Tateno, Katsutoshi Yoshizato & Tsuyoshi Yokoi. (2007) In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver. Journal of Pharmaceutical Sciences 96:2, pages 428-437.
Crossref
Maria Almira Correia & Paul R. Ortiz de Montellano. 2005. Cytochrome P450. Cytochrome P450 247 322 .
Toshimasa TanakaTeruaki OkudaYoshio Yamamoto. (2004) Characterization of the CYP3A4 Active Site by Homology Modeling. CHEMICAL & PHARMACEUTICAL BULLETIN Chemical and Pharmaceutical Bulletin 52:7, pages 830-835.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.