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Xenobiotica
the fate of foreign compounds in biological systems
Volume 29, 1999 - Issue 6
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Research Article

Common multiple interactions of tricyclic antidepressants and orphenadrine with liver microsomal cytochrome P450 enzymes of the rat

P. H. ROOS Institute for Physiological Chemistry, Division of Bioenergetics, MA 2} 129, Ruhr- University Bochum, D-44780 Bochum, Germany
Pages 629-640 | Published online: 22 Sep 2008

Citations (5)

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Read on this site (1)

M. Murray & K. Murray. (2003) Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines. Xenobiotica 33:10, pages 973-987.
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Articles from other publishers (4)

Jeanette Niestroy, Alfonso Barbara, Kathrin Herbst, Sandra Rode, Manuela van Liempt & Peter H. Roos. (2011) Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2. Toxicology in Vitro 25:3, pages 671-683.
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Larissa Waentig, Norbert Jakubowski & Peter H. Roos. (2011) Multi-parametric analysis of cytochrome P450 expression in rat liver microsomes by LA-ICP-MS. J. Anal. At. Spectrom. 26:2, pages 310-319.
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Peter H. Roos, Arunachalam Venkatachalam, Andreas Manz, Larissa Waentig, Christina U. Koehler & Norbert Jakubowski. (2008) Detection of electrophoretically separated cytochromes P450 by element-labelled monoclonal antibodies via laser ablation inductively coupled plasma mass spectrometry. Analytical and Bioanalytical Chemistry 392:6, pages 1135-1147.
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Thomas M. Polasek & John O. Miners. (2008) Time-dependent inhibition of human drug metabolizing cytochromes P450 by tricyclic antidepressants. British Journal of Clinical Pharmacology 65:1, pages 87-97.
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