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Xenobiotica
the fate of foreign compounds in biological systems
Volume 29, 1999 - Issue 5
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Research Article

β2-Agonist abuse in food producing animals: use of in vitro liver preparations to assess biotransformation and potential target residues for surveillance

M. J. SAUER Risk Research Department, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NB, UK
,
M. DAVE Risk Research Department, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NB, UK
,
B. G. LAKE Risk Research Department, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NB, UK
,
G. R. MANCHEE Risk Research Department, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NB, UK
,
L. C. HOWELLS Risk Research Department, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NB, UK
&
N. G. COLDHAM Risk Research Department, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NB, UK
Pages 483-497 | Published online: 22 Sep 2008

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Brian G. Lake & Roger J. Price. (2013) Evaluation of the metabolism and hepatotoxicity of xenobiotics utilizing precision-cut slices. Xenobiotica 43:1, pages 41-53.
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Articles from other publishers (12)

Lucila Cantón, Carlos Lanusse & Laura Moreno. 2022. New Aspects of Meat Quality. New Aspects of Meat Quality 785 808 .
L. Moreno & C. Lanusse. 2017. New Aspects of Meat Quality. New Aspects of Meat Quality 605 627 .
Iori Hirosawa, Mai Ishikawa, Mio Ogino, Hiroshi Ito, Takuya Hirao, Harumi Yamada, Mariko Asahi, Hajime Kotaki, Yoshimichi Sai & Ken-ichi Miyamoto. (2014) Enantioselective disposition of clenbuterol in rats. Biopharmaceutics & Drug Disposition 35:4, pages 207-217.
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K. Ko, K. Kurogi, G. Davidson, M.-Y. Liu, Y. Sakakibara, M. Suiko & M.-C. Liu. (2012) Sulfation of ractopamine and salbutamol by the human cytosolic sulfotransferases. Journal of Biochemistry 152:3, pages 275-283.
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Anna Alonen, Minna Gartman, Olli Aitio, Moshe Finel, Jari Yli-Kauhaluoma & Risto Kostiainen. (2009) Synthesis, structure characterization, and enzyme screening of clenbuterol glucuronides. European Journal of Pharmaceutical Sciences 37:5, pages 581-587.
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N. Van Hoof, R. Schilt, E. van der Vlis, P. Boshuis, M. Van Baak, A. Draaijer, K. De Wasch, M. Van de Wiele, J. Van Hende, D. Courtheyn & H. De Brabander. (2005) Detection of zilpaterol (Zilmax®) in calf urine and faeces with liquid chromatography–tandem mass spectrometry. Analytica Chimica Acta 529:1-2, pages 189-197.
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Clare Joyce, W. Franklin Smyth, Venkataraman N. Ramachandran, Edmund O’Kane & Daniel J. Coulter. (2004) The characterisation of selected drugs with amine-containing side chains using electrospray ionisation and ion trap mass spectrometry and their determination by HPLC–ESI-MS. Journal of Pharmaceutical and Biomedical Analysis 36:3, pages 465-476.
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S. Sivapathasundaram, L. C. Howells, M. J. Sauer & C. Ioannides. (2004) Functional integrity of precision-cut liver slices from deer and cattle. Journal of Veterinary Pharmacology and Therapeutics 27:2, pages 79-84.
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Sarah L. Henrikson & Bonnie R. Rush. (2001) Efficacy of salmeterol xinafoate in horses with recurrent airway obstruction. Journal of the American Veterinary Medical Association 218:12, pages 1961-1965.
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Pizzariello Andrea, Stred’ansky Miroslav, Stred’anska Silvia & Miertuš Stanislav. (2001) A solid binding matrix/molecularly imprinted polymer-based sensor system for the determination of clenbuterol in bovine liver using differential-pulse voltammetry. Sensors and Actuators B: Chemical 76:1-3, pages 286-294.
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C. NEBBIA. (2001) Biotransformation Enzymes as Determinants of Xenobiotic Toxicity in Domestic Animals. The Veterinary Journal 161:3, pages 238-252.
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Carole Lerche-Langrand & Herve J. Toutain. (2000) Precision-cut liver slices: characteristics and use for in vitro pharmaco-toxicology. Toxicology 153:1-3, pages 221-253.
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