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Xenobiotica
the fate of foreign compounds in biological systems
Volume 29, 1999 - Issue 4
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Research Article

Preclinical and in vitro assessment of the potential of D0870, an antifungal agent, for producing clinical drug interactions

D. McKILLOP Drug Kinetics Group, Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield SK10 4TG, UK
,
D. J. BACK Drug Kinetics Group, Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield SK10 4TG, UK
,
A. D. McCORMICK Drug Kinetics Group, Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield SK10 4TG, UK
,
J. A. EVANS Drug Kinetics Group, Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield SK10 4TG, UK
&
J. TJIA Drug Kinetics Group, Safety of Medicines Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield SK10 4TG, UK
Pages 395-408 | Published online: 22 Sep 2008

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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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Articles from other publishers (4)

Onur Dagliyan, I. Halil Kavakli & Metin Turkay. (2009) Classification of Cytochrome P450 Inhibitors with Respect to Binding Free Energy and pIC 50 Using Common Molecular Descriptors . Journal of Chemical Information and Modeling 49:10, pages 2403-2411.
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Roberta G. Susnow & Steven L. Dixon. (2003) Use of Robust Classification Techniques for the Prediction of Human Cytochrome P450 2D6 Inhibition. Journal of Chemical Information and Computer Sciences 43:4, pages 1308-1315.
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A. David Rodrigues, Gregory A. Winchell & Michael R. Dobrinska. (2013) Use of In Vitro Drug Metabolism Data to Evaluate Metabolic Drug‐Drug Interactions in Man: The Need for Quantitative Databases. The Journal of Clinical Pharmacology 41:4, pages 368-373.
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Shigeki Matsumoto & Yasushi Yamazoe. (2008) Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine. British Journal of Clinical Pharmacology 51:2, pages 133-142.
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