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Xenobiotica
the fate of foreign compounds in biological systems
Volume 29, 1999 - Issue 3
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Research Article

Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes

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Pages 217-229 | Published online: 22 Sep 2008

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Donald J. AbrahamJeffrey M. Brown, Jie Jack Li & Michael W. Sinz. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 161 218 .
Shu-Feng Zhou. (2009) Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance. Clinical Pharmacokinetics 48:11, pages 689-723.
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Kazuyoshi Nozaki, Hiroshi Kitagawa, Sumihisa Kimura, Akira Kagayama & Ryuichi Arakawa. (2006) Investigation of the electrochemical oxidation products of zotepine and their fragmentation using on‐line electrochemistry/electrospray ionization mass spectrometry. Journal of Mass Spectrometry 41:5, pages 606-612.
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Mirko S. Faber, Alexander Jetter & Uwe Fuhr. (2005) Assessment of CYP1A2 Activity in Clinical Practice: Why, How, and When?. Basic & Clinical Pharmacology & Toxicology 97:3, pages 125-134.
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E. Tanaka. (2003) Toxicological interactions involving psychiatric drugs and alcohol: an update. Journal of Clinical Pharmacy and Therapeutics 28:2, pages 81-95.
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Toshihiko Kasahara, Masamichi Hashiba, Tsuyoshi Harada & Masakuni Degawa. (2002) Change in the gene expression of hepatic tamoxifen-metabolizing enzymes during the process of tamoxifen-induced hepatocarcinogenesis in female rats. Carcinogenesis 23:3, pages 491-498.
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Marja-Liisa Dahl. (2002) Cytochrome P450 Phenotyping/Genotyping in Patients Receiving Antipsychotics. Clinical Pharmacokinetics 41:7, pages 453-470.
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Zenzaburo Tozuka, Hayato Kaneko, Toshifumi Shiraga, Yasuyuki Mitani, Akio Kawamura, Akira Kagayama & Anri Aoba. (2002) Strategy for Structure Elucidation of Drug Metabolites Derived from Protonated Molecules and (MS)n Fragmentation of Zotepine, Tiaramide and their Metabolites. Drug Metabolism and Pharmacokinetics 17:4, pages 316-339.
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Maria J. Arranz, David Collier & Robert W. Kerwin. (2001) Pharmacogenetics for the Individualization of Psychiatric Treatment. American Journal of PharmacoGenomics 1:1, pages 3-10.
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Silvio Caccia. (2000) Biotransformation of Post-Clozapine Antipsychotics. Clinical Pharmacokinetics 38:5, pages 393-414.
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