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Xenobiotica
the fate of foreign compounds in biological systems
Volume 29, 1999 - Issue 3
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Research Article

Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21

Pages 243-252 | Published online: 22 Sep 2008

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Kevin A. Ford, Gregory Ryslik, Jasleen Sodhi, Jason Halladay, Dolo Diaz, Donna Dambach & Melisa Masuda. (2015) Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications. Drug Metabolism Reviews 47:3, pages 291-319.
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Yohei Kosugi & Junzo Takahashi. (2015) Species differences and substrate specificity of CYP3A heteroactivation by efavirenz. Xenobiotica 45:4, pages 345-352.
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Takushi Kanazu, Noboru Okamura, Yoshitaka Yamaguchi, Takahiko Baba & Masahiro Koike. (2005) Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug–drug interaction model rats. Xenobiotica 35:4, pages 305-317.
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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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Articles from other publishers (2)

Tyler B. Hughes, Na Le Dang, Ayush Kumar, Noah R. Flynn & S. Joshua Swamidass. (2020) Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites. Journal of Chemical Information and Modeling 60:10, pages 4702-4716.
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Takushi Kanazu, Norihito Sato, Kyoko Kadono, Akira Touchi, Yuri Takeda, Yoshitaka Yamaguchi & Takahiko Baba. (2012) Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. Biopharmaceutics & Drug Disposition 33:4, pages 195-206.
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