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Original Articles

In situ forming poly(lactic acid-co-glycolic acid) implants containing leuprolide acetate/β-cyclodextrin complexes: preparation, characterization, and in vitro drug release

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Pages 75-84 | Received 18 Mar 2015, Accepted 02 May 2015, Published online: 14 Oct 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Song Yang, Mengya Hu, Wenqing Liu, Nuohan Hou, Kaidi Yin, Chen Shen & Qing Shang. (2021) Fabrication of PLGA in situ forming implants and study on their correlation of in vitro release profiles with in vivo performances. Journal of Biomaterials Science, Polymer Edition 32:8, pages 994-1008.
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Hossein Kamali, Elham Khodaverdi, Farzin Hadizadeh, Seyed Ahmad Mohajeri, Younes Kamali & Amir Hossein Jafarian. (2019) In-vitro, ex-vivo, and in-vivo release evaluation of in situ forming buprenorphine implants using mixture of PLGA copolymers and additives. International Journal of Polymeric Materials and Polymeric Biomaterials 68:16, pages 965-977.
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Yousef Toomari & Hassan Namazi. (2016) Synthesis of supramolecular biodendrimeric β-CD-(spacer-β-CD)21 via click reaction and evaluation of its application as anticancer drug delivery agent. International Journal of Polymeric Materials and Polymeric Biomaterials 65:10, pages 487-496.
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Mehdi Rahimi, Hamid Mobedi & Aliasghar Behnamghader. (2016) In situ-forming PLGA implants loaded with leuprolide acetate/β-cyclodextrin complexes: mathematical modelling and degradation. Journal of Microencapsulation 33:4, pages 355-364.
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Articles from other publishers (9)

Xiaxia Wu, Dongfang Cheng, Yue Lu, Rong Rong, Ying Kong, Xiuzhi Wang & Baohua Niu. (2023) A liquid crystal in situ gel based on rotigotine for the treatment of Parkinson’s disease. Drug Delivery and Translational Research.
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Seyedeh Nesa Rezaeian Shiadeh, Farzin Hadizadeh, Elham Khodaverdi, Mahmoud Gorji Valokola, Saleh Rakhshani, Hossein Kamali & Ali Nokhodchi. (2023) Injectable In-Situ Forming Depot Based on PLGA and PLGA-PEG-PLGA for Sustained-Release of Risperidone: In Vitro Evaluation and Pharmacokinetics in Rabbits. Pharmaceutics 15:4, pages 1229.
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Hossein Kamali, Malihe Karimi, Mohammadreza Abbaspour, Azadeh Nadim, Farzin Hadizadeh, Elham Khodaverdi & Farhad Eisvand. (2022) Comparison of lipid liquid crystal formulation and Vivitrol® for sustained release of Naltrexone: In vitro evaluation and pharmacokinetics in rats. International Journal of Pharmaceutics 611, pages 121275.
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Hossein Kamali, Elham Khodaverdi, Ehsan Kaffash, Amir Sarem Saffari, Seyedeh Nesa Rezaeian Shiadeh, Ali Nokhodchi & Farzin Hadizadeh. (2020) Optimization and in Vitro Evaluation of Injectable Sustained-Release of Levothyroxine Using PLGA-PEG-PLGA. Journal of Pharmaceutical Innovation 16:4, pages 688-698.
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Elham Khodaverdi, Farhad Eisvand, Mohammad Sina Nezami, Seyedeh Nesa Rezaeian Shiadeh, Hossein Kamali & Farzin Hadizadeh. (2021) Injectable In-Situ Forming Depot of Doxycycline Hyclate/α-Cyclodextrin Complex Using PLGA for Periodontitis Treatment: Preparation, Characterization, and In-Vitro Evaluation. Current Drug Delivery 18:6, pages 729-740.
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Hossein Kamali, Elham Khodaverdi, Farzin Hadizadeh, Seyed Ahmad Mohajeri, Ali Nazari & Amir Hossein Jafarian. (2019) Comparison of in-situ forming composite using PLGA-PEG-PLGA with in-situ forming implant using PLGA: In-vitro, ex-vivo, and in-vivo evaluation of naltrexone release. Journal of Drug Delivery Science and Technology 50, pages 188-200.
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Hossein Kamali, Elham Khodaverdi, Farzin Hadizadeh & Seyed Ahmad Mohajeri. (2019) In-vitro, ex-vivo, and in-vivo evaluation of buprenorphine HCl release from an in situ forming gel of PLGA-PEG-PLGA using N‑methyl‑2‑pyrrolidone as solvent. Materials Science and Engineering: C 96, pages 561-575.
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Hossein Kamali, Elham Khodaverdi, Farzin Hadizadeh, Rezvan Yazdian-Robati, Ali Haghbin & Golamhossein Zohuri. (2018) An in-situ forming implant formulation of naltrexone with minimum initial burst release using mixture of PLGA copolymers and ethyl heptanoate as an additive: In-vitro, ex-vivo, and in-vivo release evaluation. Journal of Drug Delivery Science and Technology 47, pages 95-105.
Crossref
Siddhesh Juvekar & Harsha Kathpalia. (2017) Solvent removal precipitation based in situ forming implant for controlled drug delivery in periodontitis. Journal of Controlled Release 251, pages 75-81.
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