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Journal of Sex & Marital Therapy Volume 23, 1997 - Issue 3
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Original Articles

Serotonin reuptake inhibitor-induced sexual dysfunction and its treatment: A large-scale retrospective study of 596 psychiatric outpatients

Adam Keller Ashton
,
Robert Hamer
&
Raymond C. Rosen
Pages 165-175 | Published online: 14 Jan 2008

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Ahmed M. Bakr, Amro A. El-Sakka & Ahmed I. El-Sakka. (2022) Pharmaceutical management of sexual dysfunction in men on antidepressant therapy. Expert Opinion on Pharmacotherapy 23:9, pages 1051-1063.
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Heather M. Ma & Ross D. Zafonte. (2020) Amantadine and memantine: a comprehensive review for acquired brain injury. Brain Injury 34:3, pages 299-315.
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Alan Riley. (2010) Double blind trial of yohimbine hydrochloride in the treatment of erection inadequacy: an update. Sexual and Relationship Therapy 25:4, pages 392-396.
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DanielleL. Cohen & Jay Belsky. (2008) Avoidant romantic attachment and female orgasm: testing an emotion-regulation hypothesis. Attachment & Human Development 10:1, pages 1-10.
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SuzanneL. West, LisaC. Vinikoor & Denniz Zolnoun. (2004) A Systematic Review of the Literature on Female Sexual Dysfunction Prevalence and Predictors. Annual Review of Sex Research 15:1, pages 40-172.
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Michael Gitlin. (2003) Sexual dysfunction with psychotropic drugs. Expert Opinion on Pharmacotherapy 4:12, pages 2259-2269.
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Vanessa Pesce, StuartN. Seidman & StevenP. Roose. (2002) Depression, antidepressants and sexual functioning in men. Sexual and Relationship Therapy 17:3, pages 281-287.
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J. Bobes, M. P. González, M. T. Bascarán, A. Clayton, M. Garcia, F. Rico-Villade Moros & S. Banús. (2002) Evaluating Changes in Sexual Functioning in Depressed Patients: Sensitivity to Change of the CSFQ. Journal of Sex & Marital Therapy 28:2, pages 93-103.
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Leonore Tiefer. (2001) A new view of women's sexual problems: Why new? Why now?. The Journal of Sex Research 38:2, pages 89-96.
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J. Bobes, M. P. Gonzalez, F. Rico-Villandemoros, M. T. Bascaran, P. Sarasa, A. Clayton. (2000) Validation of the Spanish Version of the Changes in Sexual Functioning Questionnaire (CSFQ). Journal of Sex & Marital Therapy 26:2, pages 119-131.
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Sanjay Gupta, Prakash Masand, AdamK Ashton & SarahL. Berry. (1999) Phenelzine-induced sexual dysfunction treated with sildenafil. Journal of Sex & Marital Therapy 25:2, pages 131-135.
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A.G. Alcántara. (1999) A possible dopaminergic mechanism in the serotonergic antidepressant-induced sexual dysfunctions. Journal of Sex & Marital Therapy 25:2, pages 125-129.
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Brian E. Moore & Anthony J. Rothschild. (1999) Treatment of Antidepressant-Induced Sexual Dysfunction. Hospital Practice 34:1, pages 89-96.
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AdamK. Ashton & RaymondC. Rosen. (1998) Accommodation to serotonin reuptake inhibitor-induced sexual dysfunition. Journal of Sex & Marital Therapy 24:3, pages 191-192.
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James M. Ellison. (1998) Antidepressant-Induced Sexual Dysfunction: Review, Classification, and Suggestions for Treatment. Harvard Review of Psychiatry 6:4, pages 177-189.
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Vi Nguyen, Isabella Dolendo, Maria Uloko, Tung-Chin Hsieh & Darshan Patel. (2023) Male delayed orgasm and anorgasmia: a practical guide for sexual medicine providers. International Journal of Impotence Research 36:3, pages 186-193.
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J. Nicholas Shumate, Seo Ho Song & Fabian M. Saleh. (2023) Paraphilic disorders, psychopathy, and those who sexually offend: a narrative review of treatment modalities. International Journal of Impotence Research.
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Daniele Urso, Valentina Leta & Katarina Rukavina. 2022. Sexual Dysfunction in Parkinson's Disease. Sexual Dysfunction in Parkinson's Disease 97 116 .
Emre Altintas & Murat Gül. 2022. Andrology and Sexual Medicine. Andrology and Sexual Medicine 41 87 .
Wojciech Danysz, Andrzej Dekundy, Astrid Scheschonka & Peter Riederer. (2021) Amantadine: reappraisal of the timeless diamond—target updates and novel therapeutic potentials. Journal of Neural Transmission 128:2, pages 127-169.
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Pooja A. Shah, Christine J. Park, Matthew P. Shaughnessy & Robert A. Cowles. (2021) Serotonin as a Mitogen in the Gastrointestinal Tract: Revisiting a Familiar Molecule in a New Role. Cellular and Molecular Gastroenterology and Hepatology 12:3, pages 1093-1104.
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Stanley E. Althof & Chris G. McMahon. (2016) Contemporary Management of Disorders of Male Orgasm and Ejaculation. Urology 93, pages 9-21.
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Mohan Nair. 2016. Sexual Offending. Sexual Offending 755 767 .
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. 2007. Male Sexual Dysfunction. Male Sexual Dysfunction 103 112 .
Uwe Hartmann. (2007) Depression and sexual dysfunction. The Journal of Men's Health & Gender 4:1, pages 18-25.
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K K Kim, H C Kang, S S Kim & B B Youn. (2006) Influence of weight reduction by sibutramine on female sexual function. International Journal of Obesity 30:5, pages 758-763.
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Benjamin K. Yang & Craig F. Donatucci. 2006. Male Sexual Function. Male Sexual Function 155 193 .
Chris G. McMahon. 2006. Male Sexual Function. Male Sexual Function 447 466 .
Chris G. McMahon, Marcel Waldinger, David Rowland, Pierre Assalian, Young Chan Kim, Amado Bechara & Alan Riley. 2006. Standard Practice in Sexual Medicine. Standard Practice in Sexual Medicine 188 209 .
George I. Papakostas & Maurizio Fava. 2005. Biology of Depression. Biology of Depression 87 209 .
Ronald N. Hines, Jane Adams, Germaine M. Buck, Willem Faber, Joseph F. Holson, Sandra W. Jacobson, Martin Keszler, Kenneth McMartin, Robert Taylor Segraves, Lynn T. Singer, I. Glenn Sipes & Paige L. Williams. (2004) NTP‐CERHR Expert Panel Report on the reproductive and developmental toxicity of fluoxetine. Birth Defects Research Part B: Developmental and Reproductive Toxicology 71:4, pages 193-280.
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Crossref
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Razmic S GregorianJr.Jr., Katharine A Golden, Asena Bahce, Clifford Goodman, W Jacqueline Kwong & Zeba M Khan. (2016) Antidepressant-Induced Sexual Dysfunction. Annals of Pharmacotherapy 36:10, pages 1577-1589.
Crossref
S. Kasper & J.P. Olié. (2020) A meta-analysis of randomized controlled trials of tianeptine versus SSRI in the short-term treatment of depression. European Psychiatry 17:S3, pages 331s-340s.
Crossref
Victor J. Malatesta & Henry E. Adams. 2001. Comprehensive Handbook of Psychopathology. Comprehensive Handbook of Psychopathology 713 748 .
S.William Tam, Manuel Worcel & Michael Wyllie. (2001) Yohimbine: a clinical review. Pharmacology & Therapeutics 91:3, pages 215-243.
Crossref
Kenneth Mah & Yitzchak M Binik. (2001) The nature of human orgasm: a critical review of major trends. Clinical Psychology Review 21:6, pages 823-856.
Crossref
H. GEORGE NURNBERG. (2001) Managing Treatment-Emergent Sexual Dysfunction Associated with Serotonergic Antidepressants: Before and After Sildenafil. Journal of Psychiatric Practice 7:2, pages 92-108.
Crossref
David S Baldwin. (2001) Depression and sexual dysfunction. British Medical Bulletin 57:1, pages 81-99.
Crossref
Domeena C. Renshaw. (2016) Women Coping with a Partner’s Sexual Avoidance. The Family Journal 9:1, pages 11-16.
Crossref
M. Philipp, J.W.G. Tiller, D. Baier & R. Kohnen. (2000) Comparison of moclobemide with selective serotonin reuptake inhibitors (SSRIs) on sexual function in depressed adults. European Neuropsychopharmacology 10:5, pages 305-314.
Crossref
Stuart N. Seidman & Steven P. Roose. (2000) The relationship between depression and erectile dysfunction. Current Psychiatry Reports 2:3, pages 201-205.
Crossref
H. George Nurnberg, Paula L. Hensley & John Lauriello. (2000) Sildenafil in the Treatment of Sexual Dysfunction Induced by Selective Serotonin Reuptake Inhibitors. CNS Drugs 13:5, pages 321-335.
Crossref
Martin Kafka. (2014) Psychopharmacologic Treatments for Nonparaphilic Compulsive Sexual Behaviors. CNS Spectrums 5:1, pages 49-59.
Crossref
Victoria Hendrick, Michael Gitlin, Lori Altshuler & Stanley Korenman. (2000) Antidepressant medications, mood and male fertility. Psychoneuroendocrinology 25:1, pages 37-51.
Crossref
. (1999) Letters to the Editor. The Canadian Journal of Psychiatry 44:9, pages 921-929.
Crossref
ADAM KELLER ASHTON. (1999) Sildenafil Treatment of Paroxetine-Induced Anorgasmia in a Woman. American Journal of Psychiatry 156:5, pages 800-800.
Crossref
Raymond C. Rosen, Roger M. Lane & Matthew Menza. (1999) Effects of SSRIs on Sexual Function. Journal of Clinical Psychopharmacology 19:1, pages 67-85.
Crossref
Sanjay Gupta, Thomas Droney, Prakash Masand & Adam K. Ashton. (1999) SSRI‐induced sexual dysfunction treated with sildenafil. Depression and Anxiety 9:4, pages 180-182.
Crossref
Stephen B. LevineStephen B. Levine. 1998. Sexuality in Mid-Life. Sexuality in Mid-Life 151 171 .

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