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Journal of Coordination Chemistry Volume 68, 2015 - Issue 2
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Original Articles

A thiosemicarbazone copper(II) complex as a potential anticancer agent

Zhong-Ying MaTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, ChinaView further author information
,
Jia ShaoTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, ChinaView further author information
,
Wei-Guo BaoTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, ChinaView further author information
,
Zhao-Yan QiangSchool of Basic Medicine, Tianjin Medical University, Tianjin, ChinaCorrespondence[email protected] [email protected]
View further author information
&
Jing-Yuan XuTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, ChinaCorrespondence[email protected] [email protected]
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Pages 277-294 | Received 17 Jul 2014, Accepted 25 Sep 2014, Published online: 27 Nov 2014

Citations (13)

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Jinxu Qi, Xuejiao Wang, Taichen Liu, Martha Kandawa-Schulz, Yihong Wang & Xinhua Zheng. (2020) Synthesis, antiproliferative activity and mechanism of copper(II)-thiosemicarbazone complexes as potential anticancer and antimicrobial agents. Journal of Coordination Chemistry 73:7, pages 1208-1221.
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Xiao-Tong Zhang, Zhong-Ying Ma, Chuan Zhao, Qi-Ji Zhou, Cheng-Zhi Xie & Jing-Yuan Xu. (2015) Synthesis, crystal structures, DNA binding, and cytotoxicity activities of two copper(II) complexes based on unsymmetrical tripodal ligands. Journal of Coordination Chemistry 68:13, pages 2307-2323.
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Articles from other publishers (11)

Sara Abdolmaleki, Alireza Aliabadi & Samad Khaksar. (2024) Unveiling the promising anticancer effect of copper-based compounds: a comprehensive review. Journal of Cancer Research and Clinical Oncology 150:4.
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Vipin Singh, Vishnunarayanan Namboothiri Vadakkedathu Palakkeezhillam, Vipin Manakkadan, Puthiyavalappil Rasin, Adarsh K. Valsan, Vaishnu Suresh Kumar & Anandaram Sreekanth. (2023) Recent developments on the potential biological applications of transition metal complexes of thiosemicarbazone derivatives. Polyhedron 245, pages 116658.
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Mahsa Badrooh, Faezeh Shokrollahi, Shaghayegh Javan, Taraneh Ghasemipour, Samira Rezaei Mojdehi, Haniyeh Farahnak, Mahboubeh Jahani Sayyad Noveiri, Mohammad Hedayati & Ali Salehzadeh. (2022) Trigger of apoptosis in adenocarcinoma gastric cell line (AGS) by a complex of thiosemicarbazone and copper nanoparticles. Molecular Biology Reports 49:3, pages 2217-2226.
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Rafael A.C. Souza, Waleska R.P. Costa, Eduardo de F. Faria, Meliza A. de S. Bessa, Ralciane deP. Menezes, Carlos H.G. Martins, Pedro I.S. Maia, Victor M. Deflon & Carolina G. Oliveira. (2021) Copper(II) complexes based on thiosemicarbazone ligand: Preparation, crystal structure, Hirshfeld surface, energy framework, antiMycobacterium activity, in silico and molecular docking studies. Journal of Inorganic Biochemistry 223, pages 111543.
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Narendra Kumar Singh, Anupa A Kumbhar, Yuba Raj Pokharel & Paras Nath Yadav. (2020) Anticancer potency of copper(II) complexes of thiosemicarbazones. Journal of Inorganic Biochemistry 210, pages 111134.
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G. Kalaiarasi, S. Rex Jeya Rajkumar, S. Dharani, Nigam P. Rath & R. Prabhakaran. (2019) In vitro cytotoxicity of new water soluble copper(II) metallates containing 7-hydroxy-4-oxo-4H-chromene thiosemicarbazones. Polyhedron 173, pages 114120.
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Mani Kaushal, Tarlok S. Lobana, Lovedeep Nim, Ritu Bala, Daljit S. Arora, Isabel Garcia-Santos, Courtney E. Duff & Jerry P. Jasinski. (2019) Synthesis of 2-acetylpyridine- N -substituted thiosemicarbazonates of copper( ii ) with high antimicrobial activity against methicillin resistant S. aureus , K. pneumoniae 1 and C. albicans . New Journal of Chemistry 43:29, pages 11727-11742.
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Claudia C. Gatto, Marcio A. S. Chagas, Iariane J. Lima, Francyelli Mello Andrade, Hugo D. Silva, Gabrielly R. Abrantes & Elisângela P. S. Lacerda. (2019) Copper(II) complexes with pyridoxal dithiocarbazate and thiosemicarbazone ligands: crystal structure, spectroscopic analysis and cytotoxic activity. Transition Metal Chemistry 44:4, pages 329-340.
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Mohammad Azarkish, Alireza Akbari, Tahereh Sedaghat & Jim Simpson. (2018) Ternary complexes of Zn(II) and Cu(II) with 1-((2-hydroxynaphthalen-1-yl)methylene)-4-phenylthiosemicarbazide in the presence of heterocyclic bases as auxiliary ligands: Synthesis, spectroscopic and structural characterization and antibacterial activity. Journal of Molecular Structure 1156, pages 34-42.
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Mohamed Wehbe, Ada W. Y. Leung, Michael J. Abrams, Chris Orvig & Marcel B. Bally. (2017) A Perspective – can copper complexes be developed as a novel class of therapeutics?. Dalton Transactions 46:33, pages 10758-10773.
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Shayna Sandhaus, Rosella Taylor, Tiffany Edwards, Alexis Huddleston, Ykeysha Wooten, Ramaiyer Venkatraman, Ralph T. Weber, Antonio González-Sarrías, Patrick M. Martin, Patrice Cagle, Yuk-Ching Tse-Dinh, Stephen J. Beebe, Navindra Seeram & Alvin A. Holder. (2016) A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα. Inorganic Chemistry Communications 64, pages 45-49.
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