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Original Articles

Rapid Communication METABOLISM OF STYRENE BY HUMAN LIVER AND LUNG

Pages 591-595 | Published online: 30 Nov 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Pavel Vodicka, Mikko Koskinen, Alessio Naccarati, Barbara Oesch-Bartlomowicz, Ludmila Vodickova, Kari Hemminki & Franz Oesch. (2006) Styrene Metabolism, Genotoxicity, and Potential Carcinogenicity. Drug Metabolism Reviews 38:4, pages 805-853.
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Joshua T. Cohen, Gary Carlson, Gail Charnley, David Coggon, Elizabeth Delzell, John D. Graham, Helmut Greim, Daniel Krewski, Michele Medinsky, Richard Monson, Dennis Paustenbach, Barbara Petersen, Stephen Rappaport, Lorenz Rhomberg, P. Barry Ryan & Kimberly Thompson. (2002) A COMPREHENSIVE EVALUATION OF THE POTENTIAL HEALTH RISKS ASSOCIATED WITH OCCUPATIONAL AND ENVIRONMENTAL EXPOSURE TO STYRENE. Journal of Toxicology and Environmental Health, Part B 5:1-2, pages 1-263.
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Igor Linhart. (2001) Stereochemistry of styrene biotransformation*. Drug Metabolism Reviews 33:3-4, pages 353-367.
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Articles from other publishers (16)

Marcy I. Banton & Satinder S. Sarang. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 763 774 .
F. Oesch, E. Fabian & Robert Landsiedel. (2019) Xenobiotica-metabolizing enzymes in the lung of experimental animals, man and in human lung models. Archives of Toxicology 93:12, pages 3419-3489.
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Thomas HillIIIIII & Rory B Conolly. (2019) Development of a Novel AOP for Cyp2F2-Mediated Lung Cancer in Mice. Toxicological Sciences 172:1, pages 1-10.
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George Cruzan, James S. Bus, Melvin E. Andersen, Gary P. Carlson, Marcy I. Banton, Satinder S. Sarang & Robbie Waites. (2018) Based on an analysis of mode of action, styrene-induced mouse lung tumors are not a human cancer concern. Regulatory Toxicology and Pharmacology 95, pages 17-28.
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Johannes Georg Filser & Heinz-Peter Gelbke. (2016) An evaluation of concentrations of styrene-7,8-oxide in rats and humans resulting from exposure to styrene or styrene-7,8-oxide and potential genotoxicity. Toxicology Letters 247, pages 11-28.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 286 290 .
Moiz M. Mumtaz & Hana R. Pohl. 2012. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 361 379 .
Gary P. Carlson. (2008) Critical appraisal of the expression of cytochrome P450 enzymes in human lung and evaluation of the possibility that such expression provides evidence of potential styrene tumorigenicity in humans. Toxicology 254:1-2, pages 1-10.
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Jou-Ku Chung, Wei Yuan, Guangxian Liu & Jiang Zheng. (2006) Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells. Toxicology 226:2-3, pages 99-106.
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A. Długosz, E. Sawicka & Z. Marchewka. (2005) Styrene and ethylene glycol have a synergetic effect on lipid peroxidation that is better protected than repaired by CoQ10. Toxicology in Vitro 19:5, pages 581-588.
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Patrick L. Sheets, Garold S. Yost & Gary P. Carlson. (2004) Benzene metabolism in human lung cell lines BEAS‐2B and A549 and cells overexpressing CYP2F1. Journal of Biochemical and Molecular Toxicology 18:2, pages 92-99.
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Christina R. Wilson, John-Michael Sauer, Gary P. Carlson, Reidar Wallin, Michael P. Ward & Stephen B. Hooser. (2003) Species comparison of vitamin K1 2,3-epoxide reductase activity in vitro: kinetics and warfarin inhibition. Toxicology 189:3, pages 191-198.
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D.F.V Lewis, B.G Lake, M.G Bird, G.D Loizou, M Dickins & P.S Goldfarb. (2003) Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions. Toxicology in Vitro 17:1, pages 93-105.
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David F. V. Lewis, Craig Sams & George D. Loizou. (2003) A quantitative structure–activity relationship analysis on a series of alkyl benzenes metabolized by human cytochrome P450 2E1. Journal of Biochemical and Molecular Toxicology 17:1, pages 47-52.
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George Cruzan, Gary P. Carlson, Keith A. Johnson, Larry S. Andrews, Marcy I. Banton, Christopher Bevan & Janette R. Cushman. (2002) Styrene Respiratory Tract Toxicity and Mouse Lung Tumors Are Mediated by CYP2F-Generated Metabolites. Regulatory Toxicology and Pharmacology 35:3, pages 308-319.
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Johannes G. Filser, Winfried Kessler & György A. Csanády. (2002) Estimation of a possible tumorigenic risk of styrene from daily intake via food and ambient air. Toxicology Letters 126:1, pages 1-18.
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