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Original Articles

DETERMINATION OF BIOKINETIC INTERACTIONS IN CHEMICAL MIXTURES USING REAL-TIME BREATH ANALYSIS AND PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING

Pages 653-670 | Published online: 30 Nov 2010

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RichardH. Mckee, ArleanM. Medeiros & WayneC. Daughtrey. (2005) A proposed methodology for setting occupational exposure limits for hydrocarbon solvents. Journal of Occupational and Environmental Hygiene 2:10, pages 524-542.
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Jane Ellen Simmons, MarinaV. Evans & WilliamK. Boyes. (2005) Moving From External Exposure Concentration to Internal Dose: Duration Extrapolation Based on Physiologically Based Pharmacokinetic Derived Estimates of Internal Dose. Journal of Toxicology and Environmental Health, Part A 68:11-12, pages 927-950.
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JamesE. Dennison, PhilipL. Bigelow, MoizM. Mumtaz, MelvinE. Andersen, IvanD. Dobrev & RaymondS.H. Yang. (2005) Evaluation of Potential Toxicity from Co-Exposure to Three CNS Depressants (Toluene, Ethylbenzene, and Xylene) Under Resting and Working Conditions Using PBPK Modeling. Journal of Occupational and Environmental Hygiene 2:3, pages 127-135.
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Articles from other publishers (10)

. 2010. Mixture Toxicity. Mixture Toxicity 229 269 .
Sami Haddad, Robert Tardif, Jonathan Boyd & Kannan Krishnan. 2010. Quantitative Modeling in Toxicology. Quantitative Modeling in Toxicology 83 105 .
Weihsueh A. Chiu, Miles S. Okino & Marina V. Evans. (2009) Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach. Toxicology and Applied Pharmacology 241:1, pages 36-60.
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Kannan Krishnan, Sastry Isukapalli & Jonathan Boyd. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Jane C. Caldwell, Nagalakshmi Keshava & Marina V. Evans. (2007) Difficulty of mode of action determination for trichloroethylene: An example of complex interactions of metabolites and other chemical exposures. Environmental and Molecular Mutagenesis 49:2, pages 142-154.
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A. Długosz, E. Sawicka & Z. Marchewka. (2005) Styrene and ethylene glycol have a synergetic effect on lipid peroxidation that is better protected than repaired by CoQ10. Toxicology in Vitro 19:5, pages 581-588.
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Ho-Yuan Chang, Yuan-Der Yun, Yi-Chun Yu, Tung-Sheng Shih, Ming-Song Lin, Hsien-Wen Kuo & Kuo-Ming Chen. (2005) The effects of simultaneous exposure to methyl ethyl ketone and toluene on urinary biomarkers of occupational N,N-dimethylformamide exposure. Toxicology Letters 155:3, pages 385-395.
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George D. Loizou & Martin Spendiff. (2004) A human PBPK model for ethanol describing inhibition of gastric motility. The Histochemical Journal 35:7, pages 687-696.
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James E Dennison, Melvin E Andersen, Ivan D Dobrev, Moiz M Mumtaz & Raymond S.H Yang. (2004) PBPK modeling of complex hydrocarbon mixtures: gasoline. Environmental Toxicology and Pharmacology 16:1-2, pages 107-119.
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Erica R. Thaler, David W. Kennedy & C. William Hanson. (2018) Medical Applications of Electronic Nose Technology: Review of Current Status. American Journal of Rhinology 15:5, pages 291-295.
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