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Original Articles

REDUCED ANTIOXIDANT DEFENSE CAPACITY IN MYOCARDIAL TISSUE FROM GUINEA PIGS TREATED WITH 5-FLUOROURACIL

Pages 585-589 | Published online: 30 Nov 2010

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Matthew Anaka & Omar Abdel-Rahman. (2022) Managing 5FU Cardiotoxicity in Colorectal Cancer Treatment. Cancer Management and Research 14, pages 273-285.
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Nergis Akba&#;Halis Süley. (2023) Potent Protective Effect of Lacidipine, Carvacrol and Lacidipine-Carvacrol Combination Against 5-Fluorouracil-Induced Cardiotoxicity in Rats. International Journal of Pharmacology 19:3, pages 321-328.
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Paweł Uruski, Julia Matuszewska, Aleksandra Leśniewska, Daniel Rychlewski, Arkadiusz Niklas, Justyna Mikuła-Pietrasik, Andrzej Tykarski & Krzysztof Książek. (2023) An integrative review of nonobvious puzzles of cellular and molecular cardiooncology. Cellular & Molecular Biology Letters 28:1.
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Marwa M. M. Refaie, Sayed Shehata, Asmaa M. A. Bayoumi, Nashwa Fathy Gamal El-Tahawy & Walaa Yehia Abdelzaher. (2021) The IL-6/STAT Signaling Pathway and PPARα Are Involved in Mediating the Dose-Dependent Cardioprotective Effects of Fenofibrate in 5-Fluorouracil-Induced Cardiotoxicity. Cardiovascular Drugs and Therapy 36:5, pages 817-827.
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Zehua Liang, Yuquan He & Xin Hu. (2022) Cardio-Oncology: Mechanisms, Drug Combinations, and Reverse Cardio-Oncology. International Journal of Molecular Sciences 23:18, pages 10617.
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Zhenkun Fu, Zhoujun Lin, Mao Yang & Chenggang Li. (2022) Cardiac Toxicity From Adjuvant Targeting Treatment for Breast Cancer Post-Surgery. Frontiers in Oncology 12.
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Azher Arafah, Muneeb U. Rehman, Ajaz Ahmad, Khalid M. AlKharfy, Saeed Alqahtani, Basit L. Jan & Nada M. Almatroudi. (2022) Myricetin (3,3′,4′,5,5′,7-Hexahydroxyflavone) Prevents 5-Fluorouracil-Induced Cardiotoxicity. ACS Omega 7:5, pages 4514-4524.
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Michał Jurczyk, Magdalena Król, Aleksandra Midro, Magdalena Kurnik-Łucka, Adrian Poniatowski & Krzysztof Gil. (2021) Cardiotoxicity of Fluoropyrimidines: Epidemiology, Mechanisms, Diagnosis, and Management. Journal of Clinical Medicine 10:19, pages 4426.
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Liliana Maria Radulescu, Dan Radulescu, Tudor-Eliade Ciuleanu, Dana Crisan, Elena Buzdugan, Dragos-Mihai Romitan & Anca Dana Buzoianu. (2021) Cardiotoxicity Associated with Chemotherapy Used in Gastrointestinal Tumours. Medicina 57:8, pages 806.
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Luis Alberto More, Sarah Lane & Aarti Asnani. (2021) 5-FU Cardiotoxicity: Vasospasm, Myocarditis, and Sudden Death. Current Cardiology Reports 23:3.
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Francesco Sabbatino, Valeria Conti, Luigi Liguori, Giovanna Polcaro, Graziamaria Corbi, Valentina Manzo, Vincenzo Tortora, Chiara Carlomagno, Carmine Vecchione, Amelia Filippelli & Stefano Pepe. (2021) Molecules and Mechanisms to Overcome Oxidative Stress Inducing Cardiovascular Disease in Cancer Patients. Life 11:2, pages 105.
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Xingbang Wang, Yong Xiao, Mingming Huang, Bing Shen, Haowei Xue & Kaile Wu. (2021) Effect of TRPM2-Mediated Calcium Signaling on Cell Proliferation and Apoptosis in Esophageal Squamous Cell Carcinoma. Technology in Cancer Research & Treatment 20, pages 153303382110452.
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Andrada Larisa Deac, Claudia Cristina Burz, Ioana Corina Bocsan & Anca Dana Buzoianu. (2020) Fluoropyrimidine-induced cardiotoxicity. World Journal of Clinical Oncology 11:12, pages 1008-1017.
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Radwa Nasser Muhammad, Nada Sallam & Hanan Salah El-Abhar. (2020) Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin. Scientific Reports 10:1.
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Dong Jin Kim, M. T. Jeena, Ok-Hee Kim, Ha-Eun Hong, Haeyeon Seo, Ja-Hyoung Ryu & Say-June Kim. (2020) Novel Therapeutic Application of Self-Assembly Peptides Targeting the Mitochondria in In Vitro and In Vivo Experimental Models of Gastric Cancer. International Journal of Molecular Sciences 21:17, pages 6126.
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Maria Principia Scavo, Annalisa Cutrignelli, Nicoletta Depalo, Elisabetta Fanizza, Valentino Laquintana, Giampietro Gasparini, Gianluigi Giannelli & Nunzio Denora. (2020) Effectiveness of a Controlled 5-FU Delivery Based on FZD10 Antibody-Conjugated Liposomes in Colorectal Cancer In vitro Models. Pharmaceutics 12:7, pages 650.
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Jaya Kanduri, Luis Alberto More, Anuradha Godishala & Aarti Asnani. (2019) Fluoropyrimidine-Associated Cardiotoxicity. Cardiology Clinics 37:4, pages 399-405.
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Xiaonan Zhang, Yaping Zhu, Shaoyang Dong, Ao Zhang, Yanmin Lu, Yanyang Li, Shichao Lv & Junping Zhang. (2019) Role of oxidative stress in cardiotoxicity of antineoplastic drugs. Life Sciences 232, pages 116526.
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Ana Reis-Mendes, Félix Carvalho, Fernando Remião, Emília Sousa, Maria de Lourdes Bastos & Vera Marisa Costa. (2019) The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells. Biomolecules 9:3, pages 98.
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Ashley Zehnder, Jennifer Graham & Gunther Antonissen. (2018) Update on Cancer Treatment in Exotics. Veterinary Clinics of North America: Exotic Animal Practice 21:2, pages 465-509.
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Ilaria Depetris, Donatella Marino, Alessandro Bonzano, Celeste Cagnazzo, Roberto Filippi, Massimo Aglietta & Francesco Leone. (2018) Fluoropyrimidine-induced cardiotoxicity. Critical Reviews in Oncology/Hematology 124, pages 1-10.
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Jaskanwal D. Sara, Jasvinder Kaur, Ryan Khodadadi, Muneeb Rehman, Ronstan Lobo, Sakti Chakrabarti, Joerg Herrmann, Amir Lerman & Axel Grothey. (2018) 5-fluorouracil and cardiotoxicity: a review. Therapeutic Advances in Medical Oncology 10, pages 175883591878014.
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Jorge Farías, Víctor Molina, Rodrigo Carrasco, Andrea Zepeda, Elías Figueroa, Pablo Letelier & Rodrigo Castillo. (2017) Antioxidant Therapeutic Strategies for Cardiovascular Conditions Associated with Oxidative Stress. Nutrients 9:9, pages 966.
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Barbara Bassani, Antonino Bruno, Nicoletta Macrì, Paola Corradino, Douglas M. Noonan & Adriana Albini. 2017. Manual of Cardio-oncology. Manual of Cardio-oncology 107 122 .
Eman Taha Mohamed & Ghada Mohamed Safwat. (2016) Evaluation of cardioprotective activity of Lepidium sativum seed powder in albino rats treated with 5-fluorouracil. Beni-Suef University Journal of Basic and Applied Sciences 5:2, pages 208-215.
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Chiara Focaccetti, Antonino Bruno, Elena Magnani, Desirée Bartolini, Elisa Principi, Katiuscia Dallaglio, Eraldo O. Bucci, Giovanna Finzi, Fausto Sessa, Douglas M. Noonan & Adriana Albini. (2015) Effects of 5-Fluorouracil on Morphology, Cell Cycle, Proliferation, Apoptosis, Autophagy and ROS Production in Endothelial Cells and Cardiomyocytes. PLOS ONE 10:2, pages e0115686.
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Anne Polk, Kirsten Vistisen, Merete Vaage-Nilsen & Dorte L Nielsen. (2014) A systematic review of the pathophysiology of 5-fluorouracil-induced cardiotoxicity. BMC Pharmacology and Toxicology 15:1.
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Duncan T. Vincent, Yasmine F. Ibrahim, Michael Graham Espey & Yuichiro J. Suzuki. (2013) The role of antioxidants in the era of cardio-oncology. Cancer Chemotherapy and Pharmacology 72:6, pages 1157-1168.
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Luisa P. Molteni, Irene Rampinelli, Massimiliano Cergnul, Ugo Scaglietti, Anna M. Paino, Douglas M. Noonan, Eraldo O. Bucci, Ornella Gottardi & Adriana Albini. (2010) Capecitabine in Breast Cancer: The Issue of Cardiotoxicity During Fluoropyrimidine Treatment. The Breast Journal 16, pages S45-S48.
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Anna Tankiewicz-Kwedlo, Dariusz Pawlak, Tomasz Domaniewski & Włodzimierz Buczko. (2010) Effect of erythropoietin, 5-fluorouracil and SN-38 on the growth of DLD-1 cells. Pharmacological Reports 62:5, pages 926-937.
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M. Manzano, P. Bueno, R. Rueda, C.L. Ramirez-Tortosa, P.A. Prieto & J.M. Lopez-Pedrosa. (2007) Intestinal Toxicity Induced by 5-Fluorouracil in Pigs: A New Preclinical Model. Chemotherapy 53:5, pages 344-355.
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P Tsibiribi, C Bui-Xuan, B Bui-Xuan, C Lombard-Bohas, S Duperret, M Belkhiria, A Tabib, G Maujean, J Descotes & Q Timour. (2016) Cardiac lesions induced by 5-fluorouracil in the rabbit. Human & Experimental Toxicology 25:6, pages 305-309.
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Adam J Chicco, Carole M Schneider & Reid Hayward. (2006) Exercise Training Attenuates Acute Doxorubicin-Induced Cardiac Dysfunction. Journal of Cardiovascular Pharmacology 47:2, pages 182-189.
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Ki-Hyun Cho, Sung-Min Choi, Byeong-Chae Kim, Seung-Han Lee, Man-Seok Park, Myeong-Kyu Kim & Jong-Keun Kim. (2004) 5-fluorouracil-induced oligodendrocyte death and inhibitory effect of cycloheximide, trolox, and Z-VAD-FMK in murine cortical culture. Cancer 100:7, pages 1484-1490.
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