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Original Articles

MICROCYSTINS (CYANOBACTERIAL TOXINS) IN DRINKING WATER ENHANCE THE GROWTH OF ABERRANT CRYPT FOCI IN THE MOUSE COLON

Pages 155-165 | Published online: 30 Nov 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Cong Wen, Shuilin Zheng, Yue Yang, Xiaoyu Li, Jihua Chen, Xiaoyan Wang, Xiangling Feng & Fei Yang. (2019) Effects of microcystins-LR on genotoxic responses in human intestinal epithelial cells (NCM460). Journal of Toxicology and Environmental Health, Part A 82:21, pages 1113-1119.
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Chengcheng Zhang, Isaac Yaw Massey, Yan Liu, Feiyu Huang, Ruihuan Gao, Ming Ding, Lin Xiang, Chuning He, Jia Wei, Yunhui Li, Yuliang Ge & Fei Yang. (2019) Identification and characterization of a novel indigenous algicidal bacterium Chryseobacterium species against Microcystis aeruginosa. Journal of Toxicology and Environmental Health, Part A 82:15, pages 845-853.
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Zorica Svirčev, Jelena Lujić, Zoran Marinović, Damjana Drobac, Nada Tokodi, Bratislav Stojiljković & Jussi Meriluoto. (2015) Toxicopathology Induced by Microcystins and Nodularin: A Histopathological Review. Journal of Environmental Science and Health, Part C 33:2, pages 125-167.
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Zorica Svirčev, Damjana Drobac, Nada Tokodi, Zorana Lužanin, Ana Marija Munjas, Branislava Nikolin, Dušan Vuleta & Jussi Meriluoto. (2014) Epidemiology of Cancers in Serbia and Possible Connection with Cyanobacterial Blooms. Journal of Environmental Science and Health, Part C 32:4, pages 319-337.
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Z. Svirčev, V. Baltić, M. Gantar, M. Juković, D. Stojanović & M. Baltić. (2010) Molecular Aspects of Microcystin-induced Hepatotoxicity and Hepatocarcinogenesis. Journal of Environmental Science and Health, Part C 28:1, pages 39-59.
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RonaldW. Zurawell, JeffI. Goldberg, CharlesF. B. Holmes & EllieE. Prepas. (2007) Tissue Distribution and Oral Dose Effects of Microcystin in the Freshwater Pulmonate Snail Lymnaea stagnalis jugularis (Say). Journal of Toxicology and Environmental Health, Part A 70:7, pages 620-626.
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M. Bruno, M. Fiori, D. Mattei, S. Melchiorre, V. Messineo, F. Volpi, S. Bogialli & M. Nazzari. (2006) ELISA and LC-MS/MS methods for determining cyanobacterial toxins in blue-green algae food supplements. Natural Product Research 20:9, pages 827-834.
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Ronald W. Zurawell, Charles F. B. Holmes & Ellie E. Prepas. (2006) Elimination of the Cyanobacterial Hepatotoxin Microcystin from the freshwater Pulmonate Snail Lymnaea stagnalis jugularis (SAY). Journal of Toxicology and Environmental Health, Part A 69:4, pages 303-318.
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RonaldW. Zurawell, Huirong Chen, JaniceM. Burke & EllieE. Prepas. (2005) Hepatotoxic Cyanobacteria: A Review of the Biological Importance of Microcystins in Freshwater Environments. Journal of Toxicology and Environmental Health, Part B 8:1, pages 1-37.
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SusanB. Watson. (2004) AQUATIC TASTE AND ODOR: A PRIMARY SIGNAL OF DRINKING-WATER INTEGRITY. Journal of Toxicology and Environmental Health, Part A 67:20-22, pages 1779-1795.
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LorraineC. Backer. (2002) Cyanobacterial Harmful Algal Blooms (CyanoHABs): Developing a Public Health Response. Lake and Reservoir Management 18:1, pages 20-31.
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Wen-Xing Ding, Han-Ming Shen & Choon-Nam Ong. (2001) CRITICAL ROLE OF REACTIVE OXYGEN SPECIES FORMATION IN MICROCYSTIN-INDUCED CYTOSKELETON DISRUPTION IN PRIMARY CULTURED HEPATOCYTES. Journal of Toxicology and Environmental Health, Part A 64:6, pages 507-519.
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Emily F. Pierce & Astrid Schnetzer. (2023) Microcystin Concentrations, Partitioning, and Structural Composition during Active Growth and Decline: A Laboratory Study. Toxins 15:12, pages 684.
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Suryakant Niture, Sashi Gadi, Qi Qi, Leslimar Rios-Colon, Sabin Khatiwada, Vandana, Reshan A. Fernando, Keith E. Levine & Deepak Kumar. (2023) Cyanotoxins Increase Cytotoxicity and Promote Nonalcoholic Fatty Liver Disease Progression by Enhancing Cell Steatosis. Toxins 15:7, pages 411.
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Aminu Surajo Usman, Faradina Merican, Syazana Zaki, Paul Broady, Peter Convey & Narongrit Muangmai. (2022) Microcystin production by oscillatorialean cyanobacteria isolated from cryopreserved Antarctic mats. Harmful Algae 120, pages 102336.
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Meihong Guo, Lei Yang, Xiaonan Zhao, Pinru Yan, Mengjiao Zhu, Weidong Ding, Dongmei Li, Xiaodong Han & Jiang Wu. (2022) Microcystin-LR inhibits early pregnancy by impairing the vascular network of luteum: Involvement of the MEK/ERK/SP1/VEGFR2 axis. Food and Chemical Toxicology 170, pages 113454.
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Halima Abdullahi, Yahuza Tanimu, Suwebat Ayanronke Akinyemi, Maria do Carmo Bittencourt-Oliveira & Mathias Ahii Chia. (2022) Assessment of microcystins in surface water and irrigated vegetables in Kwaru stream, Hayin Danmani, Kaduna-Nigeria. Environmental Science and Pollution Research 29:52, pages 78303-78313.
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Yuning Zhang, Jiancao Gao, Zhijuan Nie, Haojun Zhu, Jinliang Du, Liping Cao, Nailin Shao, Yi Sun, Shengyan Su, Gangchun Xu & Pao Xu. (2022) Microcystin-LR induces apoptosis in Juvenile Eriocheir sinensis via the mitochondrial pathway. Ecotoxicology and Environmental Safety 238, pages 113528.
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Hamed Ahari, Bahareh Nowruzi, Amir Ali Anvar & Samaneh Jafari Porzani. (2022) The Toxicity Testing of Cyanobacterial Toxins In vivo and In vitro by Mouse Bioassay: A Review . Mini-Reviews in Medicinal Chemistry 22:8, pages 1131-1151.
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Mousa O. Germoush, Maged M. A. Fouda, Mohamed Kamel & Mohamed M. Abdel-Daim. (2021) Spirulina platensis protects against microcystin-LR-induced toxicity in rats. Environmental Science and Pollution Research 29:8, pages 11320-11331.
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Yoshihito Koto, Hideaki Kawahara, Koichi Kurata, Keisuke Yoshikiyo, Ayumi Hashiguchi, Kunihiro Okano, Norio Sugiura, Kazuya Shimizu & Hidehisa Shimizu. (2022) Microcystin-LR incorporated into colonic cells through probenecid-sensitive transporters leads to upregulated MCP-1 expression induced by JNK activation. Toxicology Reports 9, pages 937-944.
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Vladimír Frišták, H. Dail LaughinghouseIVIV & Stephen M. Bell. (2020) The Use of Biochar and Pyrolysed Materials to Improve Water Quality through Microcystin Sorption Separation. Water 12:10, pages 2871.
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Chanchan Xiao, Fanbiao Mei, Guanhua Ren, Long Long, Maojian Chen, Xiang Fang, Jilin Li, Kezhi Li, Yanping Tang, Tianren Huang & Wei Deng. (2020) Synergistic Effect of MC-LR and C-Terminal Truncated HBx on HepG2 Cells and Their Effects on PP2A Mediated Downstream Target of MAPK Signaling Pathway. Frontiers in Genetics 11.
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Todd R. Miller, Ame Xiong, Jonathan R. Deeds, Whitney L. Stutts, Ingunn A. Samdal, Kjersti E. Løvberg & Christopher O. Miles. (2020) Microcystin Toxins at Potentially Hazardous Levels in Algal Dietary Supplements Revealed by a Combination of Bioassay, Immunoassay, and Mass Spectrometric Methods. Journal of Agricultural and Food Chemistry 68:30, pages 8016-8025.
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Syazana Zaki, Faradina Merican, Narongrit Muangmai, Peter Convey & Paul Broady. (2020) Discovery of microcystin-producing Anagnostidinema pseudacutissimum from cryopreserved Antarctic cyanobacterial mats. Harmful Algae 93, pages 101800.
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Sutapa Sarkar, Firas Alhasson, Diana Kimono, Muayad Albadrani, Ratanesh K. Seth, Shuo Xiao, Dwayne E. Porter, Geoff I. Scott, Bryan Brooks, Mitzi Nagarkatti, Prakash Nagarkatti & Saurabh Chatterjee. (2020) Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis. Environmental Toxicology and Pharmacology 73, pages 103281.
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Jin-Xia Wu, Hui Huang, Lei Yang, Xiao-Feng Zhang, Shen-Shen Zhang, Hao-Hao Liu, Yue-Qin Wang, Le Yuan, Xue-Min Cheng, Dong-Gang Zhuang & Hui-Zhen Zhang. (2018) Gastrointestinal toxicity induced by microcystins. World Journal of Clinical Cases 6:10, pages 344-354.
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