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Journal of Toxicology and Environmental Health, Part A
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Volume 57, 1999 - Issue 5
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Original Articles

EFFECT OF ENTEROHEPATIC CIRCULATION ON THE PHARMACOKINETICS OF CHLORAL HYDRATE AND ITS METABOLITES IN F344 RATS

J. L. Merdink, R. D. Stenner, D. K. Stevens, J. C. Parker, R. J. Bull
Pages 357-368 | Published online: 30 Nov 2010

Citations (9)

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LawrenceH. Lash, DavidA. Putt & JeanC. Parker. (2006) Metabolism and Tissue Distribution of Orally Administered Trichloroethylene in Male and Female Rats: Identification of Glutathione- and Cytochrome P-450-Derived Metabolites in Liver, Kidney, Blood, and Urine. Journal of Toxicology and Environmental Health, Part A 69:13, pages 1285-1309.
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Articles from other publishers (8)

Tarek Manasfi, Michel De Méo, Carole Di Giorgio, Bruno Coulomb & Jean-Luc Boudenne. (2017) Assessing the genotoxicity of two commonly occurring byproducts of water disinfection: Chloral hydrate and bromal hydrate. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 813, pages 37-44.
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Lawrence H. Lash, Weihsueh A. Chiu, Kathryn Z. Guyton & Ivan Rusyn. (2014) Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity. Mutation Research/Reviews in Mutation Research 762, pages 22-36.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 136 .
Weihsueh A. Chiu, Miles S. Okino & Marina V. Evans. (2009) Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach. Toxicology and Applied Pharmacology 241:1, pages 36-60.
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Dorleta Otaegui, Alicia Rodríguez-Gascón, Aizpea Zubia, Fernando P. Cossío & José Luis Pedraz. (2008) Pharmacokinetics and tissue distribution of Kendine 91, a novel histone deacetylase inhibitor, in mice. Cancer Chemotherapy and Pharmacology 64:1, pages 153-159.
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J.L. Merdink, L.M. Robison, D.K. Stevens, M. Hu, J.C. Parker & R.J. Bull. (2008) Kinetics of chloral hydrate and its metabolites in male human volunteers. Toxicology 245:1-2, pages 130-140.
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Thomas C Schmitt. (2002) Determination of chloral hydrate and its metabolites in blood plasma by capillary gas chromatography with electron capture detection. Journal of Chromatography B 780:2, pages 217-224.
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Michael R Pranzatelli & Elizabeth D Tate. (2001) Chloral hydrate for progressive myoclonus epilepsy: a new look at an old drug. Pediatric Neurology 25:5, pages 385-389.
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