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Drug and Chemical Toxicology Volume 43, 2020 - Issue 1
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Research Article

Thyme (Thymus vulgaris) leaf extract modulates purinergic and cholinergic enzyme activities in the brain homogenate of 5-fluorouracil administered rats

Stephen Adeniyi AdefeghaFunctional Food and Nutraceutical Unit, Department of Biochemistry, Federal University of Technology, Akure, Nigeria; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-1339-403X
ORCID Icon,
Sunday Idowu OyeleyeFunctional Food and Nutraceutical Unit, Department of Biochemistry, Federal University of Technology, Akure, Nigeria; ;Department of Biomedical Technology, Federal University of Technology, Akure, Nigeria
,
Abimbola AkintemiFunctional Food and Nutraceutical Unit, Department of Biochemistry, Federal University of Technology, Akure, Nigeria;
,
Bathlomew Maduka OkekeFunctional Food and Nutraceutical Unit, Department of Biochemistry, Federal University of Technology, Akure, Nigeria;
&
Ganiyu ObohFunctional Food and Nutraceutical Unit, Department of Biochemistry, Federal University of Technology, Akure, Nigeria;
Pages 43-50 | Received 13 May 2019, Accepted 18 Aug 2019, Published online: 02 Sep 2019

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Ganiyu Oboh, Bukola Christiana Adedayo, Mayowa Blessing Adetola, Idowu Sunday Oyeleye & Opeyemi Babatunde Ogunsuyi. (2022) Characterization and neuroprotective properties of alkaloid extract of Vernonia amygdalina Delile in experimental models of Alzheimer’s disease. Drug and Chemical Toxicology 45:2, pages 731-740.
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Sunday I. Oyeleye, Opeyemi B. Ogunsuyi, Odunayo O. Oluokun & Ganiyu Oboh. (2023) Seeds of moringa (Moringa oleifera) and mucuna (Mucuna pruriens L.) modulate biochemical indices of L-NAME-induced hypertension in rats: A comparative study. Journal of Agriculture and Food Research, pages 100624.
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Idowu S. Oyeleye, Adeniyi S. Adefegha, Olajide R. Ojo, Omoyemi A. Akintemi & Ganiyu Oboh. (2023) Ameliorative effect of extracts from scent (Ocimum basilicum), mentha (Mentha piperita), and thyme (Thymus vulgaris) leafy spices on glycemic, purinergic molecules, and oxidative status in renal tissue of diabetic rats. Comparative Clinical Pathology 32:4, pages 681-689.
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Sunday Idowu Oyeleye, Tosin Abiola Olasehinde, Olamide Wilson Fasakin, Ganiyu Oboh & Jamiyu Ayodeji-John Saliu. (2022) Phyllanthus amarus Schumach. & Thonn. and Momordica charantia L extracts improve memory function, attenuate cholinergic and purinergic dysfunction, and suppress oxidative stress in the brain of doxorubicin–treated rats. Phytomedicine Plus 2:2, pages 100283.
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Emmanuel Ayodeji Ayeni, Yuzhou Gong, Hao Yuan, Yikao Hu, Xiaolin Bai & Xun Liao. (2022) Medicinal Plants for Anti-neurodegenerative diseases in West Africa. Journal of Ethnopharmacology 285, pages 114468.
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Felix Abayomi Dada, Sunday Idowu Oyeleye, Stephen Adeniyi Adefegha, Leye Jonathan Babatola & Adeniyi Adebayo. (2021) Evaluation of different almond ( Terminalia catappa ) extracts against oxidative stress induced by cyclosporine in brain and liver of rats . Journal of Complementary and Integrative Medicine 18:4, pages 727-735.
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Shamprasad Varija Raghu, Avinash Kundadka Kudva, Suresh Rao, Krishna Prasad, Jayesh Mudgal & Manjeshwar Shrinath Baliga. (2021) Dietary agents in mitigating chemotherapy-related cognitive impairment (chemobrain or chemofog): first review addressing the benefits, gaps, challenges and ways forward. Food & Function 12:22, pages 11132-11153.
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Erinda Lika, Marija Kostić, Sunčica Vještica, Ivan Milojević & Nikola Puvača. (2021) Honeybee and Plant Products as Natural Antimicrobials in Enhancement of Poultry Health and Production. Sustainability 13:15, pages 8467.
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Felix Abayomi Dada, Sunday Idowu Oyeleye, Stephen Adeniyi Adefegha & Ganiyu Oboh. (2020) Extracts from Almond ( Terminalia catappa ) leaf and stem bark mitigate the activities of crucial enzymes and oxidative stress associated with hypertension in cyclosporine A‐stressed rats . Journal of Food Biochemistry 45:3.
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Esther Emem Nwanna, Sunday Idowu Oyeleye & Ganiyu Oboh. (2020) Editan ( Lasianthera africana ) leaf‐inclusive diets modulate some neuronal enzyme activities and antioxidant status of cyclophosphamide‐treated Wistar rats . Journal of Food Biochemistry 45:3.
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Bukola C. Adedayo, Sunday I. Oyeleye, Bathlomew M. Okeke & Ganiyu Oboh. (2020) Anti‐cholinesterase and antioxidant properties of alkaloid and phenolic‐rich extracts from pawpaw ( Carica papaya ) leaf: A comparative study . Flavour and Fragrance Journal 36:1, pages 47-54.
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