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Drug and Chemical Toxicology Volume 45, 2022 - Issue 1
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Research Article

Suppression of glomerular damage and apoptosis and biomarkers of acute kidney injury induced by acetaminophen toxicity using a combination of resveratrol and quercetin

Mohammad Dallaka Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi ArabiaView further author information
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Amal F. Dawoodb Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia;c Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
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Mohamed A. Haidaraa Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia;c Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
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Dina H. Abdel Kaderd Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
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Refaat A. Eide Department of Pathology, College of Medicine, King Khalid University, Abha, Saudi ArabiaView further author information
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Samaa S. Kamard Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
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Asmaa M. Shams Eldeenc Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, EgyptORCID Iconhttps://orcid.org/0000-0002-4250-0818View further author information
ORCID Icon &
Bahjat Al-Ania Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi ArabiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5773-1160View further author information
ORCID Icon show all
Pages 1-7 | Received 09 Aug 2019, Accepted 14 Jan 2020, Published online: 03 Feb 2020

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Amal T. Abou-Elghait, Rania M. Al Adly, Eman Radwan & Fatma Y. Meligy. (2024) Metformin modulates autophagic pathway in renal fibrosis induced by carbon tetrachloride in adult male albino rats. Ultrastructural Pathology 48:3, pages 153-171.
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Articles from other publishers (18)

Qingchen Cui, Xiaoying Song, Liping Zhou, Junjie Dong, Yanjun Wei, Zongtao Liu & Xianggen Wu. (2024) Fabrication of resveratrol-loaded soy protein isolate-glycyrrhizin nanocomplex for improving bioavailability via pH-responsive hydrogel properties. International Journal of Biological Macromolecules 258, pages 128950.
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Moamen Elsafty, Ahmed Abdeen & Mohamed Aboubakr. (2023) Allicin and Omega-3 fatty acids attenuates acetaminophen mediated renal toxicity and modulates oxidative stress, and cell apoptosis in rats. Naunyn-Schmiedeberg's Archives of Pharmacology 397:1, pages 317-328.
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Hina Rashid, Abdulmajeed Jali, Mohammad Suhail Akhter & Sayed Aliul Hasan Abdi. (2023) Molecular Mechanisms of Oxidative Stress in Acute Kidney Injury: Targeting the Loci by Resveratrol. International Journal of Molecular Sciences 25:1, pages 3.
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Mingxin Guo, Jiaqi Zeng, Zhangzhang Sun, Xia Wu & Zhiqiang Hu. (2023) Research Progress on Quercetin's Biological Activity and Structural Modification Based on Its Antitumor Effects. ChemistrySelect 8:41.
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Bahjat Al-Ani, Norah M. Alzamil, Peter W. Hewett, Fahaid Al-Hashem, Ismaeel Bin-Jaliah, Abdullah S. Shatoor, Samaa S. Kamar, Noha S. Abdel Latif, Mohamed A. Haidara & Amal F. Dawood. (2021) Metformin ameliorates ROS-p53-collagen axis of fibrosis and dyslipidemia in type 2 diabetes mellitus-induced left ventricular injury. Archives of Physiology and Biochemistry 129:3, pages 734-740.
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Md. Abdul Alim Al-Bari, Manoj B. Menon & Nabil Eid. (2023) Editorial: Emerging mechanistic insights of selective and Nonselective Autophagy in liver and gut diseases and their treatment strategies in the era of COVID-19. Frontiers in Pharmacology 14.
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Sumaira Yousuf, Shabnam Shabir, Mohammad Murtaza Mehdi, Shailesh Srivastav, Zuhair M. Mohammedsaleh, Zaid Bassfar, Mohammed M. Jalal, Mamdoh S. Moawadh, Yahya F. Jamous, Sandeep Kumar Singh, Emanuel Vamanu & Mahendra P. Singh. (2023) Investigation of the Protective Effects of Urtica dioica, Capsella bursa-pastoris and Inula racemosa on Acetaminophen-Induced Nephrotoxicity in Swiss Albino Male Mice. Applied Sciences 13:6, pages 3925.
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Mohammad Y. Alshahrani, Hasnaa A. Ebrahim, Saeed M. Alqahtani, Nervana M. Bayoumy, Samaa S. Kamar, Asmaa M. ShamsEldeen, Mohamed A. Haidara, Bahjat Al-Ani & Alia Albawardi. (2023) Metformin Suppresses Thioacetamide-Induced Chronic Kidney Disease in Association with the Upregulation of AMPK and Downregulation of Oxidative Stress and Inflammation as Well as Dyslipidemia and Hypertension. Molecules 28:6, pages 2756.
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Walla'a Osman, Gomaa Mostafa-He, Ahmed Osman, Laila Rashed & Dina Labib. (2022) Effect of Arabic Gum (Acacia senegal) on Paracetamol-Induced Chronic Nephrotoxicity in Albino Rats. International Journal of Pharmacology 18:8, pages 1593-1604.
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Yi-Qin Chen, Hao-Yin Chen, Qin-Qi Tang, Yi-Fan Li, Xu-Sheng Liu, Fu-Hua Lu & Yue-Yu Gu. (2022) Protective effect of quercetin on kidney diseases: From chemistry to herbal medicines. Frontiers in Pharmacology 13.
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Amal F. Dawood, Norah M. Alzamil, Peter W. Hewett, Maha A. Momenah, Mohammad Dallak, Samaa S. Kamar, Dina H. Abdel Kader, Hanaa Yassin, Mohamed A. Haidara, Amro Maarouf & Bahjat Al-Ani. (2022) Metformin Protects against Diabetic Cardiomyopathy: An Association between Desmin–Sarcomere Injury and the iNOS/mTOR/TIMP-1 Fibrosis Axis. Biomedicines 10:5, pages 984.
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Íris Guerreiro, Cíntia Ferreira-Pêgo, Diogo Carregosa, Cláudia N. Santos, Regina Menezes, Ana S. Fernandes & João G. Costa. (2022) Polyphenols and Their Metabolites in Renal Diseases: An Overview. Foods 11:7, pages 1060.
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Mingzhu Yan, Suwei Jin, Yongguang Liu, Lisha Wang, Zhi Wang, Tianji Xia & Qi Chang. (2022) Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control. Frontiers in Pharmacology 13.
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Alok K. Paul, Md K. Hossain, Tooba Mahboob, Veeranoot Nissapatorn, Polrat Wilairatana, Rownak Jahan, Khoshnur Jannat, Tohmina A. Bondhon, Anamul Hasan, Maria de Lourdes Pereira & Mohammed Rahmatullah. (2022) Does Oxidative Stress Management Help Alleviation of COVID-19 Symptoms in Patients Experiencing Diabetes?. Nutrients 14:2, pages 321.
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Chun-yan Fang, Da-yong Lou, Li-qin Zhou, Jin-cheng Wang, Bo Yang, Qiao-jun He, Jia-jia Wang & Qin-jie Weng. (2021) Natural products: potential treatments for cisplatin-induced nephrotoxicity. Acta Pharmacologica Sinica 42:12, pages 1951-1969.
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Chun Chen, Jai-Sing Yang, Chi-Cheng Lu, Yu-Tse Wu & Fu-An Chen. (2021) Effect of Quercetin on Injury to Indomethacin-Treated Human Embryonic Kidney 293 Cells. Life 11:11, pages 1134.
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Asmaa M. ShamsEldeen, Bahjat Al‐Ani, Hasnaa A. Ebrahim, Laila Rashed, Amul M. Badr, Abeer Attia, Ayman M. Farag, Samaa S. Kamar, Mohamed A. Haidara, Suliman Al Humayed & Mohammed Ali Eshra. (2021) Resveratrol suppresses cholestasis‐induced liver injury and fibrosis in rats associated with the inhibition of TGFβ1–Smad3–miR21 axis and profibrogenic and hepatic injury biomarkers. Clinical and Experimental Pharmacology and Physiology 48:10, pages 1402-1411.
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Emrah Akgun, Murat Boyacioglu & Sadiye Kum. (2021) The potential protective role of folic acid against acetaminophen-induced hepatotoxicity and nephrotoxicity in rats. Experimental Animals 70:1, pages 54-62.
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