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Drug and Chemical Toxicology Volume 45, 2022 - Issue 2
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Research Articles

Characterization and neuroprotective properties of alkaloid extract of Vernonia amygdalina Delile in experimental models of Alzheimer’s disease

Ganiyu Oboha Functional Foods and Nutraceuticals Unit of Biochemistry Department, Federal University of Technology, Akure, NigeriaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-5167-9779View further author information
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Bukola Christiana Adedayoa Functional Foods and Nutraceuticals Unit of Biochemistry Department, Federal University of Technology, Akure, NigeriaView further author information
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Mayowa Blessing Adetolaa Functional Foods and Nutraceuticals Unit of Biochemistry Department, Federal University of Technology, Akure, NigeriaView further author information
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Idowu Sunday Oyeleyea Functional Foods and Nutraceuticals Unit of Biochemistry Department, Federal University of Technology, Akure, Nigeria;b Department of Biomedical Technology, Federal University of Technology, Akure, NigeriaORCID Iconhttps://orcid.org/0000-0003-3935-2313View further author information
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Opeyemi Babatunde Ogunsuyia Functional Foods and Nutraceuticals Unit of Biochemistry Department, Federal University of Technology, Akure, Nigeria;b Department of Biomedical Technology, Federal University of Technology, Akure, NigeriaORCID Iconhttps://orcid.org/0000-0003-3075-1086View further author information
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Pages 731-740 | Received 02 Jan 2020, Accepted 18 May 2020, Published online: 16 Jun 2020

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Opeyemi B. Ogunsuyi, Tosin A. Olasehinde & Ganiyu Oboh. (2022) Neuroprotective properties of solanum leaves in transgenic Drosophila melanogaster model of Alzheimer's disease. Biomarkers 27:6, pages 587-598.
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Marjan Talebi, Eleni Kakouri, Mohsen Talebi, Petros A. Tarantilis, Tahereh Farkhondeh, Selen İlgün, Ali Mohammad Pourbagher-Shahri & Saeed Samarghandian. (2021) Nutraceuticals-based therapeutic approach: recent advances to combat pathogenesis of Alzheimer’s disease. Expert Review of Neurotherapeutics 21:6, pages 625-642.
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Smita Jain, Ritu Singh, Sarvesh Paliwal & Swapnil Sharma. (2023) Targeting Neuroinflammation as Disease Modifying Approach to Alzheimer’s Disease: Potential and Challenges. Mini-Reviews in Medicinal Chemistry 23:22, pages 2097-2116.
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Bukola C. Adedayo, Oluwapelumi M. Ajiboye, Idowu S. Oyeleye, Raymond O. Ojo & Ganiyu Oboh. (2023) Effect of alkaloid extract from Andrographis paniculata (Burm. f.) Nees and Phyllanthus amarus Schumach. & Thonn. on cognitive related biochemicals in the brain of streptozotocin-induced diabetic rats. Pharmacological Research - Modern Chinese Medicine 9, pages 100314.
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Olubunmi ATOLANİ, Priyanka Banerjee, Adedamola Elizabeth Ayenı, Muhammed Abubakar Usman, Opeyemi Jamiu Adejumo, Ochuko L. Erukaınure, Robert Preıssner, Jean Baptiste Sokoudjou, Mary Olufunmilayo Ologe, Oluyomi Stephen Adeyemı & Ifeoluwa ADEDOTUN. (2023) Phytochemical, Pharmacological, Phyto-cosmeceutical, Toxicity, and In silico Toxicological Evaluations of Vernonia amygdalina Delile – A Review. Journal of the Turkish Chemical Society Section A: Chemistry, pages 775-802.
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Acharya Balkrishna, Sonam Verma, Sumit Kumar Singh & Vedpriya Arya. (2023) Alzheimer's disease: A role of biomarkers in early diagnosis and evidences from African ethnomedicinal knowledge. European Journal of Neuroscience 58:1, pages 2406-2425.
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S. Ankul Singh & Chitra Vellapandian. (2023) The promising guide to LC–MS analysis and cholinesterase activity of Luffa cylindrica (L.) fruit using in vitro and in-silico analyses. Future Journal of Pharmaceutical Sciences 9:1.
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Samadder Chandrani & Arokiasamy Justin Thenmozhi. 2023. Nutraceuticals for Alzheimer's Disease: A Promising Therapeutic Approach. Nutraceuticals for Alzheimer's Disease: A Promising Therapeutic Approach 171 195 .
Daniel Etim Jacob, Imaobong Ufot Nelson & Sylvester Chibueze Izah. 2023. Herbal Medicine Phytochemistry. Herbal Medicine Phytochemistry 1 39 .
Damilare Emmanuel Rotimi, Goodnews Mavoghenegbero Ben-Goru, Ikponmwosa Owen Evbuomwan, Tobiloba Christiana Elebiyo, Mohammed Alorabi, Abdullah Farasani, Gaber El-Saber Batiha & Oluyomi Stephen Adeyemi. (2022) Zingiber officinale and Vernonia amygdalina Infusions Improve Redox Status in Rat Brain. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-9.
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Felix Abayomi Dada, Sunday Idowu Oyeleye, Stephen Adeniyi Adefegha, Leye Jonathan Babatola & Adeniyi Adebayo. (2021) Evaluation of different almond ( Terminalia catappa ) extracts against oxidative stress induced by cyclosporine in brain and liver of rats . Journal of Complementary and Integrative Medicine 18:4, pages 727-735.
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Moses B. Ekong & Clementina F. Iniodu. (2021) Nutritional therapy can reduce the burden of depression management in low income countries: A review. IBRO Neuroscience Reports 11, pages 15-28.
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Sunday Idowu Oyeleye, Opeyemi Babatunde Ogunsuyi, Victor Adedeji, Damilola Olatunde & Ganiyu Oboh. (2020) Citrus spp . essential oils improve behavioral pattern, repressed cholinesterases and monoamine oxidase activities, and production of reactive species in fruit fly ( Drosophila melanogaster ) model of Alzheimer’s Disease . Journal of Food Biochemistry 45:3.
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Esther Emem Nwanna, Sunday Idowu Oyeleye & Ganiyu Oboh. (2020) Editan ( Lasianthera africana ) leaf‐inclusive diets modulate some neuronal enzyme activities and antioxidant status of cyclophosphamide‐treated Wistar rats . Journal of Food Biochemistry 45:3.
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Adaze Bijou Enogieru & Oghenakhogie Iroboudu Momodu. (2021) African Medicinal Plants Useful for Cognition and Memory: Therapeutic Implications for Alzheimer’s Disease. The Botanical Review 87:1, pages 107-134.
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Adedayo O. Ademiluyi, Adeola A. Oyesomi, Opeyemi B. Ogunsuyi, Sunday I. Oyeleye & Ganiyu Oboh. (2020) Influence of cooking on the neuroprotective properties of pepper (bird pepper and cayenne pepper) varieties in scopolamine‐induced neurotoxicity in rats. Journal of Food Processing and Preservation 44:12.
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