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Drug and Chemical Toxicology Volume 45, 2022 - Issue 2
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Research Articles

Modulating effect of a hydroxychalcone and a novel coumarin–chalcone hybrid against mitomycin-induced genotoxicity in somatic cells of Drosophila melanogaster

Jefferson Hollanda Vérasa Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Universidade Federal de Goiás, Goiânia, BrazilORCID Iconhttps://orcid.org/0000-0001-9959-6411
ORCID Icon,
Camila Regina do Valea Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Universidade Federal de Goiás, Goiânia, Brazil
,
Débora Cristina da Silva Limaa Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Universidade Federal de Goiás, Goiânia, Brazil
,
Murilo Machado dos Anjosb Chemistry Institute, Universidade Federal de Goiás, Goiânia, Brazil
,
Aline Bernardesb Chemistry Institute, Universidade Federal de Goiás, Goiânia, Brazil
,
Aroldo Vieira de Moraes Filhoa Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Universidade Federal de Goiás, Goiânia, Brazil
,
Carolina Ribeiro e Silvaa Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Universidade Federal de Goiás, Goiânia, Brazil
,
Guilherme Roberto de Oliveirab Chemistry Institute, Universidade Federal de Goiás, Goiânia, Brazil
,
Caridad Noda Pérezb Chemistry Institute, Universidade Federal de Goiás, Goiânia, Brazil
&
Lee Chen-Chena Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Universidade Federal de Goiás, Goiânia, BrazilCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0386-247X
ORCID Icon show all
Pages 775-784 | Received 21 Jan 2020, Accepted 22 May 2020, Published online: 12 Jun 2020

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Ana Paula de Araújo Boleti, Pedro Hernique de Oliveira Cardoso, Breno Emanuel Farias Frihling, Zaira da Rosa Guterres, Ana Francisca Gomes da Silva, Alexandre Azenha Alves de Rezende, Fernanda Rodrigues Garcez, Walmir Silva Garcez, Ulrich Graf, Mário Antônio Spanó, Lillian May Grespan Estodutto da Silva & Ludovico Migliolo. (2023) Evaluation of in vitro and in vivo Anti-neuroinflammatory and Genotoxic Activities of the Alkaloid Tryptophol-5-O-β-D-glucopyranoside from Ocotea minarum. Journal of Biologically Active Products from Nature 13:2, pages 156-166.
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Jefferson Hollanda Véras, Camila Regina Do Vale, Elisa Flávia Luiz Cardoso Bailão, Murilo Machado Dos Anjos, Clever Gomes Cardoso, Matheus Gabriel de Oliveira, José Realino de Paula, Guilherme Roberto de Oliveira, Carolina Ribeiro E Silva & Lee Chen-Chen. (2022) Protective effects and DNA repair induction of a coumarin-chalcone hybrid against genotoxicity induced by mutagens. Journal of Toxicology and Environmental Health, Part A 85:22, pages 937-951.
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Thaís Teixeira da Silva, Júlia Braga Martins, Maria Do Socorro de Brito Lopes, Pedro Marcos de Almeida, José Luiz Silva Sá & Francielle Alline Martins. (2021) Modulating effect of DL-kavain on the mutagenicity and carcinogenicity induced by doxorubicin in Drosophila melanogaster. Journal of Toxicology and Environmental Health, Part A 84:19, pages 769-782.
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A. V. D. Melo Bisneto, L. C. D. Oliveira, A. Silva Fernandes, L. S. Silva, J. H. Véras, C. G. Cardoso, Carolina R. E Silva, A. V. de Moraes Filho, C. C. Carneiro & L. Chen-Chen. (2021) Recombinogenic, genotoxic, and cytotoxic effects of azathioprine using in vivo assays. Journal of Toxicology and Environmental Health, Part A 84:6, pages 261-271.
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Articles from other publishers (3)

Selda Öz, Zeynep Nur Sarıkaya, Özüm Larçın & Rabia Sarıkaya. (2024) Investigation of the Genotoxic Effect of Fluoxetine Hydrochloride in Drosophila melanogaster. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 27:2, pages 316-324.
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Firzan Nainu, Emil Salim, Muh. Fadhil As’ad, Deepak Chandran, Kuldeep Dhama, Ali A. Rabaan & Talha B. Emran. (2023) Fruit fly for anticancer drug discovery and repurposing. Annals of Medicine & Surgery 85:2, pages 337-342.
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Pornsiri Pitchakarn, Woorawee Inthachat, Jirarat Karinchai & Piya Temviriyanukul. (2021) Human Hazard Assessment Using Drosophila Wing Spot Test as an Alternative In Vivo Model for Genotoxicity Testing—A Review. International Journal of Molecular Sciences 22:18, pages 9932.
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