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Drug and Chemical Toxicology Volume 45, 2022 - Issue 3
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Research Articles

Alogliptin attenuates cyclophosphamide-induced nephrotoxicity: a novel therapeutic approach through modulating MAP3K/JNK/SMAD3 signaling cascade

Rania M. Salamaa Pharmacology and Toxicology Department, Faculty of Pharmacy, Misr International University (MIU), Cairo, Egypt;b Translational and Clinical Research Unit, Faculty of Pharmacy, Misr International University (MIU), Cairo, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1873-6222View further author information
ORCID Icon,
Merihane M. Nasrb Translational and Clinical Research Unit, Faculty of Pharmacy, Misr International University (MIU), Cairo, Egypt;c Pharmacy Practice and Clinical Pharmacy Department, Faculty of Pharmacy, Misr International University (MIU), Cairo, EgyptView further author information
,
Jannatullah I. Abdelhakeemb Translational and Clinical Research Unit, Faculty of Pharmacy, Misr International University (MIU), Cairo, EgyptView further author information
,
Omar K. Roshdyb Translational and Clinical Research Unit, Faculty of Pharmacy, Misr International University (MIU), Cairo, EgyptView further author information
&
Mohamed A. ElGamalb Translational and Clinical Research Unit, Faculty of Pharmacy, Misr International University (MIU), Cairo, EgyptView further author information
Pages 1254-1263 | Received 06 Mar 2020, Accepted 18 Aug 2020, Published online: 01 Sep 2020

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Ashif Iqubal, Abul Kalam Najmi, Shadab Md, Huda Mohammed Alkreathy, Javed Ali, Mansoor Ali Syed & Syed Ehtaishamul Haque. (2023) Oral delivery of nerolidol alleviates cyclophosphamide-induced renal inflammation, apoptosis, and fibrosis via modulation of NF-κB/cleaved caspase-3/TGF-β signaling molecules. Drug Delivery 30:1.
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Articles from other publishers (9)

Nehal Mohsin, Mohammad Shabib Akhtar, Saad A Alkahtani, Ismail A Walbi, Yasir Alhazmi, Md. Niyaz Alam & Alok Bhardwaj. (2024) Nephroprotective Effect of Bergapten Against Cyclophosphamide-Mediated Renal Stress, Inflammation, and Fibrosis in Wistar Rats: Probable Role of NF-kB and TGF-β1 Signaling Molecules. ACS Omega 9:16, pages 18296-18303.
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Yarini Arrebola Sánchez, Fabiola Almeida García, Daniel Ojeda del Sol, Mario E. Valdés-Tresanco, Carlos David Ortiz, Belinda Sánchez Ramírez & Isel Pascual Alonso. (2023) Dipeptidyl peptidase IV: a multifunctional enzyme with implications in several pathologies including cancer. Physical Sciences Reviews 0:0.
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Tuba Ozcan Metin, Ahmet Turk, Alper Yalcın & Ilkay Adanır. (2023) Anti-inflammatory and anti-apoptotic potential of beta-glucan on chemotherapy-induced nephrotoxicity in rats. Journal of Surgery and Medicine 7:1, pages 35-39.
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Ruili Yin, Yongsong Xu, Xin Wang, Longyan Yang & Dong Zhao. (2022) Role of Dipeptidyl Peptidase 4 Inhibitors in Antidiabetic Treatment. Molecules 27:10, pages 3055.
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Amira Ebrahim Alsemeh & Doaa M. Abdullah. (2022) Protective effect of alogliptin against cyclophosphamide-induced lung toxicity in rats: Impact on PI3K/Akt/FoxO1 pathway and downstream inflammatory cascades. Cell and Tissue Research 388:2, pages 417-438.
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Petr Busek, Jonathan S. Duke-Cohan & Aleksi Sedo. (2022) Does DPP-IV Inhibition Offer New Avenues for Therapeutic Intervention in Malignant Disease?. Cancers 14:9, pages 2072.
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Muluken Altaye Ayza, Kaleab Alemayehu Zewdie, Elias Fitsum Yigzaw, Solomon Gashaw Ayele, Bekalu Amare Tesfaye, Gebrehiwot Gebremedhin Tafere & Muzey Gebreyohannes Abrha. (2022) Potential Protective Effects of Antioxidants against Cyclophosphamide-Induced Nephrotoxicity. International Journal of Nephrology 2022, pages 1-12.
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Xueyan Yang, Jun Feng, Wei Liang, Zijing Zhu, Zhaowei Chen, Jijia Hu, Dingping Yang & Guohua Ding. (2021) Roles of SIRT6 in kidney disease: a novel therapeutic target. Cellular and Molecular Life Sciences 79:1.
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Adel M. Ahmad, Hamdoon A. Mohammed, Tarek M. Faris, Abeer S. Hassan, Hebatallah B. Mohamed, Mahmoud I. El Dosoky & Esam M. Aboubakr. (2021) Nano-Structured Lipid Carrier-Based Oral Glutathione Formulation Mediates Renoprotection against Cyclophosphamide-Induced Nephrotoxicity, and Improves Oral Bioavailability of Glutathione Confirmed through RP-HPLC Micellar Liquid Chromatography. Molecules 26:24, pages 7491.
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