Advanced search
Publication Cover
Journal of Liquid Chromatography Volume 5, 1982 - Issue 3
Journal homepage
13
Views
17
CrossRef citations to date
0
Altmetric
Original Articles

A High-Performance Liquid Chromatographic Method for the Quantitative Determination of Naproxen and Des-Methyl-Naproxen in Biological Samples

J. W. A. van Loenhout Department of Pharmacology, University Hospital St. Radboud, Geert Grooteplein Zuid 6, 6525, GA, Nijmegen, The Netherlands; Department of Rheumatology, University Hospital St. Radboud, Geert Grooteplein Zuid 6, 6525, GA, Nijmegen, The Netherlands
,
C. A. M. van Ginneken Department of Pharmacology, University Hospital St. Radboud, Geert Grooteplein Zuid 6, 6525, GA, Nijmegen, The Netherlands
,
H. C. J. Ketelaars Department of Pharmacology, University Hospital St. Radboud, Geert Grooteplein Zuid 6, 6525, GA, Nijmegen, The Netherlands
,
P. M. Kimenai Department of Pharmacology, University Hospital St. Radboud, Geert Grooteplein Zuid 6, 6525, GA, Nijmegen, The Netherlands
,
Y. Tan Department of Pharmacology, University Hospital St. Radboud, Geert Grooteplein Zuid 6, 6525, GA, Nijmegen, The Netherlands
&
F. W. J. Gribnau Department of Pharmacology, University Hospital St. Radboud, Geert Grooteplein Zuid 6, 6525, GA, Nijmegen, The Netherlands
Pages 549-561 | Published online: 06 Dec 2006

Citations (17)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Hearan Suh, H.W. Jun & G.W. Lu. (1995) Fluorometric High Performance Liquid Chromatography for Quantitation of Naproxen in Serum. Journal of Liquid Chromatography 18:15, pages 3105-3115.
Read now
Th. Karidas, A. Avgerinos & S. Malamataris. (1993) Extractionless HPLC Method for the Determination of Naproxen in Human Plasma and Urine. Analytical Letters 26:11, pages 2341-2348.
Read now
Sompon Wanwimolruk. (1990) A Simple Isocratic High-Performance Liquid Chromatographic (HPLC) Determination of Naproxen in Human Plasma using a Microbore Column Technique. Journal of Liquid Chromatography 13:8, pages 1611-1625.
Read now
F. A. Van Den Ouweland, F. H. M. Corstens, L. B. A. Van De Putte & F. W. J. Gribnau. (1987) Gastrointestinal Blood Loss During Treatment with Naproxen for Rheumatoid Arthritis. Scandinavian Journal of Rheumatology 16:5, pages 365-370.
Read now

Articles from other publishers (13)

Bilal Yilmaz, Huseyin Sahin & Ali Fuat Erdem. (2014) Determination of naproxen in human plasma by GC-MS. Journal of Separation Science 37:8, pages 997-1003.
Crossref
Paul W. Elsinghorst, Martina Kinzig, Michael Rodamer, Ulrike Holzgrabe & Fritz Sörgel. (2011) An LC–MS/MS procedure for the quantification of naproxen in human plasma: Development, validation, comparison with other methods, and application to a pharmacokinetic study. Journal of Chromatography B 879:19, pages 1686-1696.
Crossref
Yi-Hsin Hsu, Yi-Bo Liou, Jen-Ai Lee, Chau-Yang Chen & An-Bang Wu. (2006) Assay of naproxen by high-performance liquid chromatography and identification of its photoproducts by LC-ESI MS. Biomedical Chromatography 20:8, pages 787-793.
Crossref
I Pineros, P Ballesteros & J.L Lastres. (2002) Extraction and LC determination of lysine clonixinate salt in water/oil microemulsions. Journal of Pharmaceutical and Biomedical Analysis 27:5, pages 747-754.
Crossref
Hiroyuki Yokoyama, Toshiharu Horie & Shoji Awazu. (2016) Lipid Peroxidation and Cherniluminescence during Naproxen Metabolism in Rat Liver Microsomes. Human & Experimental Toxicology 13:12, pages 831-838.
Crossref
Yokoyama Hiroyuki, Horie Toshiharu & Awazu Shoji. (1993) Lipid peroxidation in rat liver microsomes during naproxen metabolism. Biochemical Pharmacology 45:8, pages 1721-1724.
Crossref
Ashok K. Singh. (1992) Quantitative analysis of inositol lipids and inositol phosphates in synaptosomes and microvessels by column chromatography: comparison of the mass analysis and the radiolabelling methods. Journal of Chromatography B: Biomedical Sciences and Applications 581:1, pages 1-10.
Crossref
Jan Vanggaard Andersen & Steen Honoré Hansen. (1992) Simultaneous determination of (R)- and (S)-naproxen and (R)- and (S)-6-O-desmethylnaproxen by high-performance liquid chromatography on a Chiral-AGP column. Journal of Chromatography B: Biomedical Sciences and Applications 577:2, pages 362-365.
Crossref
Jan Vanggaard Andersen & Steen Honoré Hansen. (1992) Simultaneous quantitative determination of naproxen, its metabolite 6-O-desmethylnaproxen and their five conjugates in plasma and urine samples by high-performance liquid chromatography on dynamically modified silica. Journal of Chromatography B: Biomedical Sciences and Applications 577:2, pages 325-333.
Crossref
Ashok K. Singh, Yin Jang, Usha Mishra & Kae Granley. (1991) Simultaneous analysis of flunixin, naproxen, ethacrynic acid, indomethacin, phenylbutazone, mefenamic acid and thiosalicycic acid in plasma and urine by high-performance liquid chromatography and gas chromatography—mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 568:2, pages 351-361.
Crossref
Claudio Giachetti, Giovanni Zanolo, Paolo Poletti & Fabio Perovanni. (1990) High resolution gas chromatography determination of twelve acidic non-steroidal antiinflammatory drugs (NSAIDs) as methyl ester derivatives in plasma. Journal of High Resolution Chromatography 13:11, pages 789-792.
Crossref
F. A. van den Ouweland, P. C. Eenhoorn, Y. Tan & F. W. J. Gribnau. (1989) Transcutaneous absorption of naproxen gel. European Journal of Clinical Pharmacology 36:2, pages 209-211.
Crossref
FA Van den Ouweland, MJ Franssen, LB Van de Putte, Y Tan, CA Van Ginneken & FW Gribnau. (2012) Naproxen pharmacokinetics in patients with rheumatoid arthritis during active polyarticular inflammation.. British Journal of Clinical Pharmacology 23:2, pages 189-193.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.