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Journal of Liquid Chromatography Volume 14, 1991 - Issue 1
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Original Articles

A Convenient Void Volume Marker for Several Chiral HPLC Columns

William H. Pirkle School of Chemical Sciences University of Illinois, Urbana, Illinois, 61801
&
Christopher J. Welch School of Chemical Sciences University of Illinois, Urbana, Illinois, 61801
Pages 1-8 | Published online: 23 Oct 2006

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Arcadius V. Krivoshein & Zhaochang Hu. (2021) Nonideal behavior of void volume markers in polar-organic chiral HPLC on polysaccharide-based chiral stationary phases. Journal of Liquid Chromatography & Related Technologies 44:9-10, pages 476-483.
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Wonjae Lee. (1999) Effect of the Amide Connecting Tether Type of Pirkle-Concept Chiral Stationary Phases Derived from (S)-N-(3,5-Dinitrobenzoyl)Leucine on Enantiomeric Separations. Analytical Letters 32:2, pages 423-432.
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Sechoing Lin. (1995) Direct Liquid Chromatographic Separation of 2,3-Dihydro-2-ethylbenzofuran-2-carboxylic Acid Enantiomers Using a Cellulose Carbamate-Based Chiral Stationary Phase Column. Journal of Liquid Chromatography 18:13, pages 2611-2619.
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Myung Ho Hyun, Chung Sik Min, Yoon Jae Cho & Myoung Seon Na. (1995) An Improved Chiral Recognition Model for Resolving N-ACYL-α-arylalkylamines on Pirkle-Type π-Acidic Chiral Stationary Phases. Journal of Liquid Chromatography 18:13, pages 2527-2541.
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M.H. Hyun, S.M. Cho, J.-J. Ryoo & M.S. Kim. (1994) A Mechanistic Evaluation for the Resolution of Enantiomers of α-Arylpropionic Acid Derivatives on π-Basic Chiral Stationary Phases. Journal of Liquid Chromatography 17:2, pages 317-328.
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W.H. Pirkle, J. Andrew Burke & K.C. Deming. (1993) The Role of Spatial Complementarity in Chiral Recognition. Journal of Liquid Chromatography 16:1, pages 161-170.
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WilliamH. Pirkle & ChristopherJ. Welch. (1992) An Improved Chiral Stationary Phase for the Chromatographic Separation of Underivatized Naproxen Enantiomers. Journal of Liquid Chromatography 15:11, pages 1947-1955.
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WilliamH. Pirkle & ChristopherJ. Welch. (1991) Chromatographic Separation of Underivatized Naproxen Enantiomers. Journal of Liquid Chromatography 14:18, pages 3387-3396.
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Articles from other publishers (49)

Bohumil Dolenský, Ameneh Tatar, Martin Havlík, Tereza Navrátilová, Jan Hajduch & Pavel Matějka. (2021) Methodology of deconvolution of total solute retention on chemically modified stationary phases to structure specific contributions of bound compounds. Journal of Chromatography A 1642, pages 462030.
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Leonid D. Asnin & Maria V. Stepanova. (2018) Van't Hoff analysis in chiral chromatography. Journal of Separation Science 41:6, pages 1319-1337.
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Robert Sheridan, Patrick Piras, Edward Sherer, Christian Roussel, William Pirkle & Christopher Welch. (2016) Mining Chromatographic Enantioseparation Data Using Matched Molecular Pair Analysis. Molecules 21:10, pages 1297.
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Dennis Åsberg, Martin Enmark, Jörgen Samuelsson & Torgny Fornstedt. (2014) Evaluation of co-solvent fraction, pressure and temperature effects in analytical and preparative supercritical fluid chromatography. Journal of Chromatography A 1374, pages 254-260.
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Yuliya K. Nikitina, Imran Ali & Leonid D. Asnin. (2014) Adsorption of aqueous organic mixtures on a chiral stationary phase with bound antibiotic eremomycin. Journal of Chromatography A 1363, pages 71-78.
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Mirlinda Biba, Erik L. Regalado, Naijun Wu & Christopher J. Welch. (2014) Effect of particle size on the speed and resolution of chiral separations using supercritical fluid chromatography. Journal of Chromatography A 1363, pages 250-256.
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Jimmy O. DaSilva, Brandyce Coes, Lisa Frey, Ingrid Mergelsberg, Ray McClain, Lisa Nogle & Christopher J. Welch. (2014) Evaluation of non-conventional polar modifiers on immobilized chiral stationary phases for improved resolution of enantiomers by supercritical fluid chromatography. Journal of Chromatography A 1328, pages 98-103.
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Ping Jiang, Di Wu & Charles A. Lucy. (2014) Determination of void volume in normal phase liquid chromatography. Journal of Chromatography A 1324, pages 63-70.
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C.J. Welch. 2014. Comprehensive Organic Synthesis II. Comprehensive Organic Synthesis II 143 159 .
Wes Schafer, Tilak Chandrasekaran, Zainab Pirzada, Chaowei Zhang, Xiaoyi Gong, Mirlinda Biba, Erik L. Regalado & Christopher J. Welch. (2013) Improved Chiral SFC Screening for Analytical Method Development. Chirality 25:11, pages 799-804.
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Min Li, Zongbi Bao, Baogen Su, Huabin Xing, Yiwen Yang & Qilong Ren. (2013) Enantiomeric separation of citalopram base by supercritical fluid chromatography. Journal of Separation Science 36:18, pages 3093-3100.
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Ray McClain, Myung Ho Hyun, Yinan Li & Christopher J. Welch. (2013) Design, synthesis and evaluation of stationary phases for improved achiral supercritical fluid chromatography separations. Journal of Chromatography A 1302, pages 163-173.
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Zhi Dai, Charles U. PittmanJr.Jr. & Tingyu Li. (2013) Enantiomeric Separation of Racemic 4‐Aryl‐1,4‐Dihydropyridines and 4‐Aryl‐1,2,3,4‐Tetrahydropyrimidines on a Chiral Tetraproline Stationary Phase. Chirality 25:4, pages 238-242.
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Zhi Dai, Charles U. PittmanJr.Jr. & Tingyu Li. (2012) Enantiomeric Recognition of Racemic 4‐Aryl‐1,4‐dihydropyridine Derivatives via Chiralpak AD‐H Stationary Phases. Chirality 24:10, pages 854-859.
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Caroline West & Eric Lesellier. (2011) Comments on the paper “Characterization of stationary phases by a linear solvation energy relationship utilizing supercritical fluid chromatography” by C. R. Mitchell, N. J. Benz, S. Zhang. Journal of Separation Science 34:15, pages 1917-1924.
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Xiaoyi Gong, Tim Craven, Wes Schafer, Zainab Pirzada, Mirlinda Biba & Christopher J. Welch. (2010) Estimating chromatographic enantioselectivity (α) from gradient enantioselective chromatography data. Chirality 23:2, pages 128-132.
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Clifford R. Mitchell, Nancy J. Benz & Shuhong Zhang. (2010) Characterization of stationary phases by a linear solvation energy relationship utilizing supercritical fluid chromatography. Journal of Separation Science 33:19, pages 3060-3067.
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Wenjian Lao & Jay Gan. (2010) Temperature effects on a doubly tethered diproline chiral stationary phase: Hold‐up volume, enantioselectivity and robustness. Journal of Separation Science 33:19, pages 3052-3059.
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Volker Friebolin, Silvia Marten & Klaus Albert. (2009) Characterization of binding affinities in a chromatographic system by suspended state HR/MAS NMR spectroscopy. Magnetic Resonance in Chemistry 48:2, pages 111-116.
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Juhyeon Jin, Myung Ho Hyun & Jung Hag Park. (2009) Chiral separation of amides of amino acid on a (S)‐ N ‐(3,5‐dinitrobenzoyl)leucine‐ N ‐phenyl‐ N ‐propylamide‐bonded silica using nonaqueous capillary electrochromatography . Journal of Separation Science 32:14, pages 2421-2425.
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In Whan Kim, Myung Ho Hyun, Jurim Gwon, Juhyeon Jin & Jung Hag Park. (2009) Enantioseparation of amino acid amides on an ( S )‐ N ‐(3,5‐dinitrobenzoyl)leucine‐ N ‐phenyl‐ N ‐propylamide‐bonded silica in normal phase CEC . ELECTROPHORESIS 30:6, pages 1015-1021.
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Ye Bao, Junmin Huang, Tingyu Li & Daniel W. Armstrong. (2007) Evaluation of Pentaproline-Based Chiral Stationary Phase by LC. Chromatographia 67:S1, pages 13-32.
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Wenjian Lao & Jay Gan. (2007) Characterization of Column Hold-Up Volume with Static and Dynamic Methods on an Immobilized Polysaccharide-Based Chiral Stationary Phase. Chromatographia 67:1-2, pages 3-7.
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Wenjian Lao & Jay Gan. (2007) Hold‐up volume and its application in estimating effective phase ratio and thermodynamic parameters on a polysaccharide‐coated chiral stationary phase. Journal of Separation Science 30:16, pages 2590-2597.
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Peter Sajonz, Xiaoyi Gong, William R. LeonardJr.Jr., Mirlinda Biba & Christopher J. Welch. (2006) Multiparallel chiral method development screening using an 8‐channel microfluidic HPLC system. Chirality 18:10, pages 803-813.
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Christopher J. Welch. 2005. Preparative Enantioselective Chromatography. Preparative Enantioselective Chromatography 1 18 .
Jae Jeong Ryoo, Kyu Sung Heo, Eun-Soon Choi, Jung Hag Park & Wonjae Lee. (2004) Enantioseparation of tiropramide by HPLC. Chirality 16:S1, pages S51-S54.
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Jae Jeong Ryoo, Kyu Sung Heo & Young Ae Song. (2003) Resolution of N-acyl-1-naphthylalkylamide on amide and sulfonamide-derived π-acidic chiral stationary phases. Microchemical Journal 74:3, pages 215-221.
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Salvatore Caccamese, Grazia Principato, Reija Jokela, Arto Tolvanen & David Din Belle. (2001) Chiral HPLC separation and CD spectra of the enantiomers of the alkaloid tacamonine and related compounds. Chirality 13:10, pages 691-693.
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Salvatore Caccamese, Alessandra Bottino, Francesca Cunsolo, Silvia Parlato & Placido Neri**. (2000) Resolution of inherently chiral calix[4]arenes with AABB and CDCD substitution patterns on the upper and lower rims, respectively. Tetrahedron: Asymmetry 11:15, pages 3103-3112.
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Anle Yang, Andrew P Gehring & Tingyu Li. (2000) Large degree of racemization observed in the amide bond forming reaction on silica gel. Journal of Chromatography A 878:2, pages 165-170.
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Myung Ho Hyun & William H Pirkle. (2000) Liquid chromatographic separation of the stereoisomers of thiazide diuretics. Journal of Chromatography A 876:1-2, pages 221-227.
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Markus Kamieth, Ulrich Burkert, Perry S. Corbin, Steven J. Dell, Steven C. Zimmerman & Frank-Gerrit Klärner. (1999) Molecular Tweezers as Synthetic Receptors: Molecular Recognition of Electron-Deficient Aromatic Substrates by Chemically Bonded Stationary Phases. European Journal of Organic Chemistry 1999:11, pages 2741-2749.
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Jae Jeong Ryoo, Sung Hyun Im, Kwang-Pill Lee, Jung Hag Park & Myung Ho Hyun. (1999) Resolution of Racemic N-Acyl-1-arylaminoalkanes on a (3,5-Dinitrobenzoyl)phenylglycinol-Derived High Performance Liquid Chromatography Chiral Stationary Phase. Microchemical Journal 63:1, pages 128-133.
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Salvatore Caccamese, Anna Notti, Sebastiano Pappalardo, Melchiorre F Parisi & Grazia Principato. (1999) Inherently chiral α-picolyloxy-p-tert-butylcalix[5]arene crown ethers: Synthesis, structure proof, and enantioselective HPLC resolution. Tetrahedron 55:17, pages 5505-5514.
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Salvatore Caccamese & Grazia Principato. (1998) Resolution of the enantiomers of tetrahydrozoline by chiral HPLC. The racemization of the enantiomers via an imine–enamine tautomerism. Tetrahedron: Asymmetry 9:16, pages 2939-2945.
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Myung Ho Hyun, Jung Bae Lee & Young Duk Kim. (1998) An Improved (S)-Leucine-Derived π-Acidic HPLC Chiral Stationary Phase for the Resolution of π-Acidic Racemates. Journal of High Resolution Chromatography 21:1, pages 69-71.
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Francoise Arnaud-Neu, Salvatore Caccamese, Saowarux Fuangswasdi, Sebastiano Pappalardo, Melchiorre F. Parisi, Ada Petringa & Grazia Principato. (1997) Synthesis, Optical Resolution and Complexation Properties of Inherently Chiral Monoalkylated p-tert -Butyl-(1,2)-calix[4]crown Ethers . The Journal of Organic Chemistry 62:23, pages 8041-8048.
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Myung Ho Hyun, Myeong Seon Na & Jong Sung Jin. (1996) Chiral recognition models for the liquid chromatographic resolution of π-acidic racemates on a chiral stationary phase derived from N-phenyl-N-alkylamide of (S-naproxen). Journal of Chromatography A 752:1-2, pages 77-84.
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Myung Ho Hyun, Myeong Seon Na & Chung-Sik Min. (1996) Improved chiral stationary phase derived from (S)-naproxen for the liquid chromatographic resolution of enantiomers. Journal of Chromatography A 732:2, pages 209-214.
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Norbert M. Maier & Georg Uray. (1996) Diphenylethanediamine derivatives as chiral selectors V1. Efficient normal-phase high-performance liquid chromatographic enantioseparation of underivatized chiral arylalcohols on four differently linked 3,5-dinitrobenzoyldiphenylethanediamine-derived chiral stationary phases. Journal of Chromatography A 732:2, pages 215-230.
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Steven C. Zimmerman & Wing‐Sum Kwan. (2003) A Comparison of Enthalpies of Formation in Solution and Enthalpies for HPLC Retention for Hydrogen‐Bonded Host—Guest Complexes. Angewandte Chemie International Edition in English 34:21, pages 2404-2406.
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Steven C. Zimmerman & Wing‐Sum Kwan. (2006) Vergleich von in Lösung und mit HPLC bestimmten Bildungsenthalpien über Wasserstoffbrücken gebundener Wirt‐Gast‐Komplexe. Angewandte Chemie 107:21, pages 2589-2592.
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Doncho P. Uzunov, Ilia Zivkovich, Erminio Costa, Alessandro Guidotti & William H. Pirkle. (1995) Enantiomeric Resolution with a New Chiral Stationary Phase of 7-Chloro-3-methyl-3,4-dihydro-2H1,2,4-benzothiadiazineS, S-Dioxide, a Cognition-Enhancing Benzothiadiazine Derivative. Journal of Pharmaceutical Sciences 84:8, pages 937-942.
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B. Chankvetadze, L. Chankvetadze, Sh. Sidamonidze, E. Yashima & Y. Okamoto. (1995) Enantioseparation of some chiral pharmaceuticals using narrow-bore liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis 13:4-5, pages 695-699.
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Myung Ho Hyun, Chung Sik Min & Yoon Jae Cho. (2005) Examples of liquid chromatographic resolution of π‐acidic racemates on a π‐acidic chiral stationary phase. Journal of High Resolution Chromatography 18:1, pages 63-65.
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N. Bargmann-Leyder, D. Thiébaut, F. Vergne, A. Bégos, A. Tambuté & M. Caude. (1994) High-speed chiral separation of beta-blockers by supercritical fluid chromatography on ChyRoSine-A. Chromatographia 39:11-12, pages 673-681.
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William H. Pirkle, Christopher J. Welch & Scott R. Wilson. (2004) Assignment of absolute configuration to an improved enantioselective naproxen selector. Chirality 6:8, pages 615-622.
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William H. Pirkle, Kris C. Deming & John A. BurkeIIIIII. (2004) A chiral stationary phase which affords unusually high levels of enantioselectivity. Chirality 3:3, pages 183-187.
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