A Simplified Method for the Determination of Methylglyoxal Bis(Guanylhydrazone), Mgbg, in Biological Fluids by Reversed-Phase Ion-Pair HPLC

A. Negro Departamento de Bioquimica y Biología Molecular

R. Méndez Departamento de Bioquimica y Biología Molecular

J. Martin-villacorta Departamento de Bioquimica y Biología Molecular

A. I. Ortiz Departamento de Fisiología, Farmacología y Toxicología Universidad de León, 24071, León, Spain

D. Ordóñez Departamento de Fisiología, Farmacología y Toxicología Universidad de León, 24071, León, Spain

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Mikko Koskinen & Hannu Elo. (1994) UV/VIS Spectrophotometric Studies on the Antileukemic Agent Glyoxal bis(Amidinohydrazone) [‘Glyoxal bis(Guanylhydrazone)’]. Spectroscopy Letters 27:7, pages 889-901.
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Ying Gao, Xiaoyi Chen, Ying Cui, Huanhuan Zhao, Ruirui Zhao, Chengbi Liu, Jian Zhao, Jinfeng Zhang & Lisheng Kong. (2022) Effects of Medium Supplements on Somatic Embryo Maturation and DNA Methylation in Pseudotsuga gaussenii Flous, a Species under Protection. Forests 13:2, pages 288.
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Ching-Ling Cheng, E-Gin Lin & Chen-Hsi Chou. (2003) Rapid and sensitive quantitation of the antiproliferative agent mitoguazone in small volumes of plasma by high-performance liquid chromatography with ultraviolet detection. Journal of Chromatography B 793:2, pages 281-289.
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M. Koskinen, H. Elo, P. Lukkari & M.-L. Riekkola. (1996) Determination of the antileukemic drug mitoguazone and seven other closely related bis(amidinohydrazones) in human blood serum by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 685:1, pages 141-149.
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Theodore W.C. Lo, Trevor Selwood & Paul J. Thornalley. (1994) The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins. Biochemical Pharmacology 48:10, pages 1865-1870.
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P. Lukkari, J. Jumppanen, K. Jinno, H. Elo & M.-L. Riekkola. (1992) Determination of bis(amidinohydrazones) by micellar electrokinetic capillary chromatography. Journal of Pharmaceutical and Biomedical Analysis 10:8, pages 561-565.
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A Simplified Method for the Determination of Methylglyoxal Bis(Guanylhydrazone), Mgbg, in Biological Fluids by Reversed-Phase Ion-Pair HPLC

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A Simplified Method for the Determination of Methylglyoxal Bis(Guanylhydrazone), Mgbg, in Biological Fluids by Reversed-Phase Ion-Pair HPLC

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