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Journal of the American Statistical Association Volume 84, 1989 - Issue 407
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Biopharmaceutical Statistic

Multiple Test Procedures in Clinical Dose Finding Studies

Michael Budde Clinical Research Department, Hoffmann-La Roche & Company, CH-4002, Basel, Switzerland
&
Peter Bauer Institute for Medical Statistics and Documentation, University of Cologne, D-5000, Cologne 41, West Germany
Pages 792-796 | Received 01 Feb 1988, Published online: 12 Mar 2012

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Wenjun Xiong & Juan Ding. (2015) A Flexible Nonparametric Test for Ordered and Umbrella Alternatives. Communications in Statistics - Simulation and Computation 44:5, pages 1257-1263.
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Thembile Mzolo, Goele Goris, Erik Talens, Alessandro Di Bucchianico & Edwin Van Den Heuvel. (2015) Statistical Process Control Methods for Monitoring In-House Reference Standards. Statistics in Biopharmaceutical Research 7:1, pages 55-65.
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Dhammika Amaratunga & Nanxiang Ge. (1998) Step-down trend tests for identifying the minimum effective dose. Journal of Biopharmaceutical Statistics 8:1, pages 151-162.
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Toshihiko Morikawa, Akira Terao & Masakazu Iwasaki. (1996) Power evaluation of various modified bonferroni procedures by a monte carlo study. Journal of Biopharmaceutical Statistics 6:3, pages 343-359.
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David-Elias Künstle, Ulrike von Luxburg & Felix A. Wichmann. (2022) Estimating the perceived dimension of psychophysical stimuli using triplet accuracy and hypothesis testing. Journal of Vision 22:13, pages 5.
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Matthias Herpers & Charalabos-Markos Dintsios. (2018) Methodological problems in the method used by IQWiG within early benefit assessment of new pharmaceuticals in Germany. The European Journal of Health Economics 20:1, pages 45-57.
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Werner Brannath, Franz König & Martin Posch. (2007) The scientific work of Peter Bauer. Biometrical Journal 49:5, pages 651-653.
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Akira Wakana, Isao Yoshimura & Chikuma Hamada. (2006) A method for therapeutic dose selection in a phase II clinical trial using contrast statistics. Statistics in Medicine 26:3, pages 498-511.
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M. Hellmich & W. Lehmacher. (2005) Closure Procedures for Monotone Bi‐Factorial Dose–Response Designs. Biometrics 61:1, pages 269-276.
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Ludwig A. Hothorn & Frank Bretz. (2019) Dose–Response and Thresholds in Mutagenicity Studies: A Statistical Testing Approach. Alternatives to Laboratory Animals 31:1_suppl, pages 97-103.
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Mervyn J. Silvapulle & Pranab K. Sen. 2001. Constrained Statistical Inference. Constrained Statistical Inference 469 524 .
Ludwig A. Hothorn & Frank Bretz. (2000) One-sided Simultaneous Confidence Intervals for Effective Dose Steps in Unbalanced Designs. Biometrical Journal 42:8, pages 995-1006.
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Walter Lehmacher, Meinhard Kieser & Ludwig Hothorn. (2000) Sequential and Multiple Testing for Dose-Response Analysis. Drug Information Journal 34:2, pages 591-597.
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Iris Pigeot. (2000) Basic concepts of multiple tests — A survey. Statistical Papers 41:1, pages 3-36.
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K.-D. Wernecke & G. Kalb. 1999. Classification in the Information Age. Classification in the Information Age 596 604 .
Eli Alon, Eric Buchser, Eduardo Herrera, Frank Christiaens, Christian De Pauw, Linda Ritter, Frank Hulstaert & Vito Grimaudo. (1998) Tropisetron for Treating Established Postoperative Nausea and Vomiting. Anesthesia & Analgesia 86:3, pages 617-623.
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Eli Alon, Eric Buchser, Eduardo Herrera, Frank Christiaens, Christian De Pauw, Linda Ritter, Frank Hulstaert & Vito Grimaudo. (1998) Tropisetron for Treating Established Postoperative Nausea and Vomiting. Anesthesia & Analgesia 86:3, pages 617-623.
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Hiroyuki Uesaka. (1998) VALIDITY AND APPLICABILITY OF TESTS FOR ORDERED ALTERNATIVES WITH BINARY RESPONSE FOR A CLINICAL DOSE-RESPONSE STUDY. Journal of the Japanese Society of Computational Statistics 11:1, pages 121-136.
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Ludwig A. Hothorn. (1997) Modifications of the Closure Principle for Analyzing Toxicological Studies. Drug Information Journal 31:2, pages 403-412.
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Shimon Braun, Ernst E. van der Wall, Hakan Emanuelsson & Isaak Kobrin. (1996) Effects of a new calcium antagonist, mibefradil (Ro 40?5967), on silent ischemia in patients with stable chronic angina pectoris: A multicenter placebo-controlled study. Journal of the American College of Cardiology 27:2, pages 317-322.
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P. Bauer & J. Röhmel. (2007) An adaptive method for establishing a dose‐response relationship. Statistics in Medicine 14:14, pages 1595-1607.
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P. Bauer & M. Budde. (2007) Multiple Testing for Detecting Efficient Dose Steps. Biometrical Journal 36:1, pages 1-15.
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P. Bauer. (2016) Multiple Primary Treatment Comparisons Based on Closed Tests. Drug Information Journal 27:3, pages 643-649.
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Richard Simon. (2006) A decade of progress in statistical methodology for clinical trials. Statistics in Medicine 10:12, pages 1789-1817.
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P. Bauer. (2006) Multiple testing in clinical trials. Statistics in Medicine 10:6, pages 871-890.
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